[PDF] Top 20 H-2 antigen expression and T cell function in murine radiation chimeras
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H-2 antigen expression and T cell function in murine radiation chimeras
... viable T cells from mice 4 days after whole body exposure to 800 rads, but these cells were unable to proliferate when exposed to antigen (Sprent et ...if T cells are stimulated by antigen or ... See full document
262
Comparisons between Murine Polyomavirus and Simian Virus 40 Show Significant Differences in Small T Antigen Function
... small T antigens promote cel- lular DNA ...small T antigens are known to promote cellular DNA replication (15, ...small T antigens directly for their ability to induce S phase in the host cells, ... See full document
10
Mononucleosis and Antigen-Driven T Cell Responses Have Different Requirements for Interleukin-2 Signaling in Murine Gammaherpesvirus Infection
... ⫹ T cells underwent a dramatic expansion between days 15 and 21 ...⫹ T cells, indicating a role for IL-2 signaling in the expansion of CD8 ⫹ T cells during mononucle- osis ...⫹ T cells, ... See full document
5
Glucocorticoid mediated repression of cytokine gene transcription in human arteritis SCID chimeras
... Giant cell arteritis (GCA) is a vasculitic syndrome that pref- erentially affects medium and large-sized ...the function of the inflamma- tory infiltrate or why the disease persists subclinically de- spite ... See full document
10
Mechanisms of drug induced lupus II T cells overexpressing lymphocyte function associated antigen 1 become autoreactive and cause a lupuslike disease in syngeneic mice
... lymphocyte function- associated antigen 1 (LFA-1) (CD11a/CD18) overexpression, and concentrations of anti–CD11a insufficient to affect antigen reactivity will completely inhibit the autoreactive ... See full document
7
Chimeric antigen receptor costimulation domains modulate human regulatory T cell function
... surface expression of the classic Treg functional markers CTLA4, LAP, and CD39 after stimulation through their CAR or ...Overall, antigen stimulation of Tregs result- ed in a higher frequency of CTLA ... See full document
20
Epidermal Growth Factor Receptor Expression Licenses Type 2 Helper T Cells to Function in a T Cell Receptor Independent Fashion
... of cell types, such as macrophages, endothelial cells, and ILC2, express MHC-II molecules and could therefore potentially present pathogen-derived antigens to Th2 ...an antigen-specific interaction at the ... See full document
20
Assessment of immunosuppressive activity of human mesenchymal stem cells using murine antigen specific CD4 and CD8 T cells in vitro
... and function to various extents in xenogenic models, such as in mice and rats ...clonal murine T cell populations (derived from TCR transgenic mice), known peptide antigens, and MSCs from ... See full document
15
Harnessing endogenous miR 181a to segregate transgenic antigen receptor expression in developing versus post thymic T cells in murine hematopoietic chimeras
... gene expression by targeting complementary sequences, referred to as miRNA recognition elements (MREs), typically located in the 3′ untranslated region of ...segregate expression of chimeric antigen ... See full document
13
Human B7 H3 binds to Triggering receptor expressed on myeloid cells like transcript 2 (TLT 2) and enhances T cell responses
... B7-H3 expression is induced on some immune cells; however, its immunological function remains controversial, because both immunoenhancing and immunoinhibitory effects have been re- ported in human and mouse ... See full document
8
Genetic Regulation of Long-Term Nonprogression in E-55+ Murine Leukemia Virus Infection in Mice
... lymphocyte antigen of unknown function (18). IL2rb encodes the IL-2 receptor beta chain, a component of the IL-2 receptor and also a component of the IL-15 receptor (13, ...of T cells ... See full document
5
Differential Lymphocyte and Antibody Responses in Deer Mice Infected with Sin Nombre Hantavirus or Andes Hantavirus
... A prominent feature of hantavirus disease in humans is thrombo- cytopenia, which is used, in part, as a diagnostic indicator. Platelet counts from deer mice infected for 14 days with SNV or ANDV were not different than ... See full document
13
1-Pyrroline-5-carboxylate released by prostate Cancer cell inhibit T cell proliferation and function by targeting SHP1/cytochrome c oxidoreductase/ROS Axis
... positives, we chose PC-3, LNCaP and HK-2 cells. Interestingly, the levels of P5C in the metabolites of PC-3 and LNCaP was remarkably high compared to HK-2 cells. P5C, an N-substituted imino acid, is an ... See full document
14
Imogen 38: a novel 38 kD islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patient
... specific antigen in ...mouse cell lines showed a higher abundance of the mRNA in bTC3 insulinoma cells rela- tive to aTC2 glucagonoma cells, consistent with the results of the subtractive hybridization ... See full document
12
Antigen induced human T cell help Precursor frequency, radiation sensitivity, and allogeneic effects
... the T cells and B cells involved and in terms of the radiation sensitivity of the T cells providing help in the two ...between antigen-induced and mitogen-induced systems with regard to ... See full document
13
The human T-cell leukemia virus type I Tax protein induces apoptosis which is blocked by the Bcl-2 protein.
... Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death.. Adult T-cell leukemia antigen in an ATL cell line and[r] ... See full document
6
T cells presenting viral antigens or autoantigens induce cytotoxic T cell anergy
... lymphocyte-derived antigen is a more broadly relevant phenomenon, as we find the observations regarding CTL anergy extend to lymphocytes presenting viral flu ...antigens. T cell antigen ... See full document
13
An in vitro study of dendritic cell development from precursors
... Protein Type of protein Putative function Target DC population Reference cell Reference population 1 name CIRE Type II C-type lectin T cell interaction, migration Murine CD8a- DC Murine [r] ... See full document
227
Late-phase expression of a murine cytomegalovirus immediate-early antigen recognized by cytolytic T lymphocytes.
... First, presentation of IE target antigen is not correlated with intranuclear presence of the major IE protein, but rather with its synthesis, and second, infected fibroblasts are suscept[r] ... See full document
5
Bombay Blood Group: A Distinct Descent
... “H” Antigen is the precursor of A and B ...“h” antigen is the recessive ...of antigen on their cell ...the cell surface of the RBC‟s. The first storey consist of the ... See full document
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