[PDF] Top 20 The HeLa cell receptor for enterovirus 70 is decay-accelerating factor (CD55).
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The HeLa cell receptor for enterovirus 70 is decay-accelerating factor (CD55).
... complement receptor types 1 and 2, and C4- binding protein, is a member of the family of regulators of complement activation (RCA) (27, 34, ...a 70- to 75-kDa glycoprotein on the surface of many cell ... See full document
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Study of Coxsackie B viruses interactions with Coxsackie Adenovirus receptor and Decay-Accelerating Factor using Human CaCo-2 cell line
... viral receptor-binding sites are among the major goals of fundamental ...as cell surface receptors for ...the cell and might function as a cell–cell adhesion molecule ...bind ... See full document
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Enterovirus 70 Receptor Utilization Is Controlled by Capsid Residues That Also Regulate Host Range and Cytopathogenicity
... type 70, an etiologic agent of acute hemorrhagic conjunctivitis, may bind different cellular receptors depending on cell ...in HeLa cells and does not cause cytopathic effects. Decay ... See full document
8
Interaction between echovirus 7 and its receptor, decay-accelerating factor (CD55): evidence for a secondary cellular factor in A-particle formation.
... from HeLa or RD ...and HeLa cells sediments at approximately 135S ...the cell surface, as has been observed for other picornaviruses (14, ...the cell. Virus may be eluted directly from the ... See full document
8
Coxsackievirus A21 binds to decay-accelerating factor but requires intercellular adhesion molecule 1 for cell entry.
... Virus-cell receptor interactions are a major determinant of viral host range specificity, and the identification of specific viral receptors has greatly increased our understanding of viral ...viral ... See full document
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Decay-Accelerating Factor Binding Determines the Entry Route of Echovirus 11 in Polarized Epithelial Cells
... The six amino acid changes that differentiate EV11-207 from EV11-207R result in major differences in the mechanisms by which these viruses enter cells. Structural data indicate that these mutations map to the surface of ... See full document
11
Coxsackieviruses B1, B3, and B5 use decay accelerating factor as a receptor for cell attachment.
... cellular receptor for a hemagglutinating strain of coxsackie B3 virus (CB3) evolved through work on the capacity of picornaviruses to hemagglu- tinate human type O erythrocytes (RBCs) ...permissive HeLa ... See full document
5
Expression of Human Decay-Accelerating Factor on Intestinal Epithelium of Transgenic Mice Does Not Facilitate Infection by the Enteral Route
... of enterovirus pathogenesis—largely based on studies of poliovirus infection in nonhuman primates—in- gested virus first replicates in the alimentary tract, moves to drain- ing lymph nodes, and spreads through the ... See full document
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Sialic Acid Functions in Enterovirus 70 Binding and Infection
... additional receptor is consistent with previously reported findings for other DAF-binding human enteroviruses, which include certain variants or isolates of coxsackie B virus sero- types 1, 3, and 5 (6, 33, 35), ... See full document
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Interaction with Coxsackievirus and Adenovirus Receptor, but Not with Decay-Accelerating Factor (DAF), Induces A-Particle Formation in a DAF-Binding Coxsackievirus B3 Isolate
... the cell surface in the cold, can be recovered after exposure to low pH or after treatment with detergents ...temperatures, cell- bound virus becomes resistant to elution (47) and infectious virus cannot be ... See full document
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Determination of the Structure of a Decay Accelerating Factor-Binding Clinical Isolate of Echovirus 11 Allows Mapping of Mutants with Altered Receptor Requirements for Infection
... in cell tropism, the complete genomic sequences of viruses EV11-207M, EV11-207R, and EV11- 207C were ...unit cell dimensions of a ⫽ b ⫽ ...R factor of 22% (35% in the outer ... See full document
11
A decay-accelerating factor-binding strain of coxsackievirus B3 requires the coxsackievirus-adenovirus receptor protein to mediate lytic infection of rhabdomyosarcoma cells.
... permit cell entry (5, 8, ...The receptor-medi- ated entry of CVB3 may therefore be analogous to that of CVA21, which also binds to DAF but undergoes a conforma- tional change to capsid proteins upon binding ... See full document
5
Novel Role for Decay-Accelerating Factor in Coxsackievirus A21-Mediated Cell Infectivity
... host cell lytic infection, possibly by cross-linking DAF via specific viral capsid interactions ...clinical enterovirus isolates, actively defined roles for DAF during lytic infection of prototype en- ... See full document
6
Characterization of a temperature-sensitive defect of enterovirus type 70.
... First, infected cells were preincubated at 33°C in the presence of guanidine hydrochloride to eliminate cellular protein synthesis, and then the guanidine hydrochloride was washed off, a[r] ... See full document
9
Single Amino Acid Changes in the Virus Capsid Permit Coxsackievirus B3 To Bind Decay-Accelerating Factor
... Many coxsackievirus B isolates bind to human decay-accelerating factor (DAF) as well as to the coxsackie- virus and adenovirus receptor (CAR). The first-described DAF-binding isolate, ... See full document
8
Markedly enhanced susceptibility to experimental autoimmune myasthenia gravis in the absence of decay accelerating factor protection
... Several lines of evidence indicate that complement activation resulting from autoantibody binding to AChR is a key effector mechanism in the pathogenesis of MG. C3 activation fragments, C9, and the mem- brane attack ... See full document
7
Dr(a ) polymorphism of decay accelerating factor Biochemical, functional, and molecular characterization and production of allele specific transfectants
... restriction fragment length polymorphism. We created transfected Chinese hamster ovary cell lines expressing either the Dra or the Drb allelic form of DAF. These allele-specific transfectants were tested by ... See full document
9
Decay accelerating factor protects human tumor cells from complement mediated cytotoxicity in vitro
... melanoma cell lines were compared with respect to expression of the decay- accelerating factor (DAF), a membrane regulatory protein that protects blood cells from autologous complement ... See full document
8
Acquisition of Complement Resistance through Incorporation of CD55/Decay-Accelerating Factor into Viral Particles Bearing Baculovirus GP64
... major receptor molecule, CD4, which is localized in the lipid ...CHO cell line stably expressing human DAF and CD59 pro- teins exhibited only a 50% reduction and increase compared to the controls, ... See full document
10
Hantavirus Causing Hemorrhagic Fever with Renal Syndrome Enters from the Apical Surface and Requires Decay-Accelerating Factor (DAF/CD55)
... Immunofluorescence and flow cytometry. For immunofluorescence, cells on microporous filters were fixed with 3% paraformaldehyde–phosphate-buffered saline (PBS) or acetone and incubated with primary antibodies and ... See full document
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