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[PDF] Top 20 The UL20 gene of herpes simplex virus 1 encodes a function necessary for viral egress.

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The UL20 gene of herpes simplex virus 1 encodes a function necessary for viral egress.

The UL20 gene of herpes simplex virus 1 encodes a function necessary for viral egress.

... Lines: 1 and 2, locations within the genome of HSV-1F of the BamHI B', F', and T fragments and the UL20 and UL21 open reading frames; 3 and 4, sequence arrangements of insertion of the a[r] ... See full document

11

Binding of Herpes Simplex Virus 1 UL20 to GODZ (DHHC3) Affects Its Palmitoylation and Is Essential for Infectivity and Proper Targeting and Localization of UL20 and Glycoprotein K

Binding of Herpes Simplex Virus 1 UL20 to GODZ (DHHC3) Affects Its Palmitoylation and Is Essential for Infectivity and Proper Targeting and Localization of UL20 and Glycoprotein K

... and function of GABAergic inhibitory synapses (12, 15, ...85 gene products of HSV-1 by palmitoylation or its effects on viral infection had not been explored prior to the present ...affected ... See full document

17

Functional Hierarchy of Herpes Simplex Virus 1 Viral Glycoproteins in Cytoplasmic Virion Envelopment and Egress

Functional Hierarchy of Herpes Simplex Virus 1 Viral Glycoproteins in Cytoplasmic Virion Envelopment and Egress

... Herpes simplex virus 1 (HSV-1) viral glycoproteins gD (carboxyl terminus), gE, gK, and gM, the membrane protein UL20, and membrane-associated protein UL11 play important ... See full document

9

Role of Herpes Simplex Virus 1 Immediate Early Protein ICP22 in Viral Nuclear Egress

Role of Herpes Simplex Virus 1 Immediate Early Protein ICP22 in Viral Nuclear Egress

... erpes simplex virus 1 (HSV-1) is one of the best-studied members of the Herpesviridae family, causing a variety of dis- eases such as mucocutaneous diseases, keratitis, skin diseases, and ... See full document

10

Herpes Simplex Virus Type 1 UL51 Protein Is Involved in Maturation and Egress of Virus Particles

Herpes Simplex Virus Type 1 UL51 Protein Is Involved in Maturation and Egress of Virus Particles

... UL51 gene of herpes simplex virus type 1 (HSV-1) encodes a phosphoprotein whose homologs are conserved throughout the herpes virus ...the function of ... See full document

10

The Product of the Herpes Simplex Virus 2 UL16 Gene Is Critical for the Egress of Capsids from the Nuclei of Infected Cells

The Product of the Herpes Simplex Virus 2 UL16 Gene Is Critical for the Egress of Capsids from the Nuclei of Infected Cells

... The herpes simplex virus UL16 gene is conserved throughout the Herpesviridae and encodes a poorly understood tegument ...in virus replication insofar as the Δ16 mutant had an ⬃ ... See full document

15

The Herpes Simplex Virus Type 1 UL17 Gene Encodes Virion Tegument Proteins That Are Required for Cleavage and Packaging of Viral DNA

The Herpes Simplex Virus Type 1 UL17 Gene Encodes Virion Tegument Proteins That Are Required for Cleavage and Packaging of Viral DNA

... During herpes simplex virus type 1 (HSV-1) infection, indi- vidual viral genomes are cleaved from intranuclear con- catameric viral DNA and packaged into preassembled ... See full document

10

Replication of Herpes Simplex Virus: Egress of Progeny Virus at Specialized Cell Membrane Sites

Replication of Herpes Simplex Virus: Egress of Progeny Virus at Specialized Cell Membrane Sites

... the herpes simplex virus 1 (HSV-1) life cycle, a viral nucleocapsid buds into a vesicle of trans-Golgi network (TGN)/endosome origin, acquiring an envelope and an outer vesicular ... See full document

14

Herpes simplex virus glycoprotein K promotes egress of virus particles.

Herpes simplex virus glycoprotein K promotes egress of virus particles.

... as virus enters ...other viral component, ...cytoplasmic virus particles (33a). Furthermore, the UL20 2 mutant formed small, syncytial plaques on 143 cells, similar to those we observed when ... See full document

13

Evidence of a Role for Nonmuscle Myosin II in Herpes Simplex Virus Type 1 Egress

Evidence of a Role for Nonmuscle Myosin II in Herpes Simplex Virus Type 1 Egress

... UL49 gene and representing one of the major tegument proteins, present in approximately 1,500 to 2,000 molecules per virion ...not necessary for virus replication ...be viral assembly ... See full document

11

Nucleolin Is Required for Efficient Nuclear Egress of Herpes Simplex Virus Type 1 Nucleocapsids

Nucleolin Is Required for Efficient Nuclear Egress of Herpes Simplex Virus Type 1 Nucleocapsids

... and viral proteins; and affects various aspects of cellular functions, in- cluding transcription mediated by RNA polymerase II, rRNA gene transcription, rRNA folding, pre-rRNA maturation, as- sembly of ... See full document

12

The UL11 gene of herpes simplex virus 1 encodes a function that facilitates nucleocapsid envelopment and egress from cells.

The UL11 gene of herpes simplex virus 1 encodes a function that facilitates nucleocapsid envelopment and egress from cells.

... Because the amounts of infectious virus obtained from the medium and cell lysates of cells infected with the wild-type and restored viruses were virtually identical, we conclude that the[r] ... See full document

7

UL20 Protein Functions Precede and Are Required for the UL11 Functions of Herpes Simplex Virus Type 1 Cytoplasmic Virion Envelopment

UL20 Protein Functions Precede and Are Required for the UL11 Functions of Herpes Simplex Virus Type 1 Cytoplasmic Virion Envelopment

... of herpes simplex virus type 1 (HSV-1) from the nucleus of the infected cell to extracellular spaces involves a number of distinct steps, including primary envelopment by budding into ... See full document

12

Herpes Simplex Virus type 1 lytic viral gene expression during the establishment and maintenance of latency

Herpes Simplex Virus type 1 lytic viral gene expression during the establishment and maintenance of latency

... but viral replication in the skin increases the number of virus genomes that can gain access to neurons, and influences the size of the latent HSV-1 reservoir (Ellison et ...of viral genomes ... See full document

353

Herpes Simplex Virus Type 1 Capsids Transit by the trans-Golgi Network, Where Viral Glycoproteins Accumulate Independently of Capsid Egress

Herpes Simplex Virus Type 1 Capsids Transit by the trans-Golgi Network, Where Viral Glycoproteins Accumulate Independently of Capsid Egress

... the virus after a chase of 2 to 4 h at 31°C. The data show that the virus could indeed escape the TGN at 31°C and reach the periphery of the cells ...wt virus (K26GFP) for 7 h at 37°C and chased it ... See full document

14

Functional and Physical Interactions of the Herpes Simplex Virus Type 1 UL20 Membrane Protein with Glycoprotein K

Functional and Physical Interactions of the Herpes Simplex Virus Type 1 UL20 Membrane Protein with Glycoprotein K

... indicated virus at an MOI of ...for 1 h with 7% normal goat serum and 7% BSA in TBS (TBS blocking buffer) before incubation for 5 h with either anti-V5 (Invitrogen, Carlsbad, CA) for recognition of gK, ... See full document

14

The Primary Enveloped Virion of Herpes Simplex Virus 1: Its Role in Nuclear Egress

The Primary Enveloped Virion of Herpes Simplex Virus 1: Its Role in Nuclear Egress

... nuclear egress complex (NEC) ...a viral protein kinase in whose absence PEVs accumulate in the perinuclear ...nuclear egress emerges as a process driven by a program of multiple weak ... See full document

14

Genetic Analysis of the Role of Herpes Simplex Virus Type 1 Glycoprotein K in Infectious Virus Production and Egress

Genetic Analysis of the Role of Herpes Simplex Virus Type 1 Glycoprotein K in Infectious Virus Production and Egress

... The initial prediction of gK secondary structure indicat- ed that gK may possess four hydrophobic domains that trans- verse cellular membranes (9). Recently, differential protec- tion experiments with gK expressed in ... See full document

12

The Product of the Herpes Simplex Virus Type 1 UL25 Gene Is Required for Encapsidation but Not for Cleavage of Replicated Viral DNA

The Product of the Herpes Simplex Virus Type 1 UL25 Gene Is Required for Encapsidation but Not for Cleavage of Replicated Viral DNA

... The herpes simplex virus type 1 (HSV-1) UL25 gene contains a 580-amino-acid open reading frame that codes for an essential ...UL25 gene product is a virion component ...in ... See full document

11

The Herpes Simplex Virus Type 1 UL20 Protein and the Amino Terminus of Glycoprotein K (gK) Physically Interact with gB

The Herpes Simplex Virus Type 1 UL20 Protein and the Amino Terminus of Glycoprotein K (gK) Physically Interact with gB

... gB gene sequence cloned in a reverse orientation using Lipo- fectamine 2000 reagent (Invitrogen) according to the manufacturer’s ...⌬gK31-68 virus at a multiplicity of infection (MOI) of 5, and infected ... See full document

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