[PDF] Top 20 A Role for Herpesvirus Entry Mediator as the Receptor for Herpes Simplex Virus 1 Entry into Primary Human Trabecular Meshwork Cells
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A Role for Herpesvirus Entry Mediator as the Receptor for Herpes Simplex Virus 1 Entry into Primary Human Trabecular Meshwork Cells
... CHO-K1 cells were infected with ...TM cells leads to infectious yields of the ...CHO-K1 cells were infected with HSV-1 at ...Vero cells by plaque assay, which indicated that the viral ... See full document
7
Localization of a Binding Site for Herpes Simplex Virus Glycoprotein D on Herpesvirus Entry Mediator C by Using Antireceptor Monoclonal Antibodies
... on cells; however, in contrast to ...on cells and to block HSV ...cultured cells express various amounts of HveC on their ...on human cells might affect the inhibitory potential of anti ... See full document
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Herpes Simplex Virus Glycoprotein D Can Bind to Poliovirus Receptor-Related Protein 1 or Herpesvirus Entry Mediator, Two Structurally Unrelated Mediators of Virus Entry
... Baculovirus construction. Plasmid pBG38, containing the complete human HveC open reading frame, was used as the template in the PCR. A fragment of HveC corresponding to amino acids Gln31 to His346 was amplified. ... See full document
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Herpesvirus Entry Mediator on Radiation Resistant Cell Lineages Promotes Ocular Herpes Simplex Virus 1 Pathogenesis in an Entry Independent Manner
... radiation-resistant cells may interact with one of its natural ligands, such as LIGHT or CD160, expressed on infiltrat- ing immune cells, to promote ...and human T cells, enhancing pro- ... See full document
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Entry of Herpes Simplex Virus 1 into Epidermis and Dermal Fibroblasts Is Independent of the Scavenger Receptor MARCO
... host cells, herpes simplex virus 1 (HSV-1) initially attaches to cell surface glycosaminoglycans, followed by the requisite binding to one of several cellular receptors, leading ... See full document
13
Characterization of Sex Differences in Ocular Herpes Simplex Virus 1 Infection and Herpes Stromal Keratitis Pathogenesis of Wild-Type and Herpesvirus Entry Mediator Knockout Mice
... that herpesvirus entry mediator (HVEM), a mem- ber of the TNF superfamily, has immunomodulatory functions and promotes ocular HSV-1 pathogenesis independently of viral entry ... See full document
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Interactions between Herpesvirus Entry Mediator (TNFRSF14) and Latency-Associated Transcript during Herpes Simplex Virus 1 Latency
... he herpes simplex virus 1 (HSV-1) infects its human host through multiple routes, stimulating strong immune re- sponses that resolve the acute infection but prove unable to pre- ... See full document
11
The Murine Homolog (Mph) of Human Herpesvirus Entry Protein B (HveB) Mediates Entry of Pseudorabies Virus but Not Herpes Simplex Virus Types 1 and 2
... poliovirus receptor homolog (Mph), was found to be a receptor for the porcine alphaherpesvirus pseudorabies virus ...murine herpesvirus entry protein B (mHveB), is most similar to one ... See full document
5
Structure-Based Analysis of the Herpes Simplex Virus Glycoprotein D Binding Site Present on Herpesvirus Entry Mediator HveA (HVEM)
... mediate entry of HSV Rid1? HSV Rid1 is a virus with a single amino acid mutation in gD ...This virus is unable to use human HveA for entry, and gD from this virus exhibits a ... See full document
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Role for 3-O-Sulfated Heparan Sulfate as the Receptor for Herpes Simplex Virus Type 1 Entry into Primary Human Corneal Fibroblasts
... a receptor for HSV-1 gD (41, 57, 61, 63, 68, 69), its role in the infection of a human target cell type has remained ...of cells. Viral entry into these cells is critical ... See full document
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Examination of the Kinetics of Herpes Simplex Virus Glycoprotein D Binding to the Herpesvirus Entry Mediator, Using Surface Plasmon Resonance
... cell 1 (Fc1) of a CM5 sensor chip via primary amines according to the manufacturer’s ...flow cells, the flow rate was 50 ml/min, and the data collection rate was set to ...a 1:1 ... See full document
11
The Virological Synapse Facilitates Herpes Simplex Virus Entry into T Cells
... T cells. However, the role of the VS in the transfer of nonlympho- tropic viruses into T cells is ...unknown. Herpes simplex virus (HSV) has been shown in vitro to infect T ... See full document
13
Entry Mechanisms of Herpes Simplex Virus 1 into Murine Epidermis: Involvement of Nectin-1 and Herpesvirus Entry Mediator as Cellular Receptors
... into primary keratinocytes and ...sole receptor in primary murine keratinocytes. To address HSV-1 in- ternalization under these circumstances, we analyzed virus uptake by using electron ... See full document
13
Generation of Herpesvirus Entry Mediator (HVEM)-Restricted Herpes Simplex Virus Type 1 Mutant Viruses: Resistance of HVEM-Expressing Cells and Identification of Mutations That Rescue Nectin-1 Recognition
... on human tumor lines. We tested a small panel of human tumor cell lines to evaluate the utility of our receptor-restricted viruses in assessing the use of naturally expressed ...HT29 cells ... See full document
11
Role of Nectin-1 and Herpesvirus Entry Mediator as Cellular Receptors for Herpes Simplex Virus 1 on Primary Murine Dermal Fibroblasts
... of primary dermal fibroblasts, we observed that entry was slower in the absence of nectin-1 than when it was present, although the number of infected cells was not ...the entry steps ... See full document
10
HveA (Herpesvirus Entry Mediator A), a Coreceptor for Herpes Simplex Virus Entry, also Participates in Virus-Induced Cell Fusion
... bind cells but fail to penetrate (6, 14, 27, 44). Cells devoid of specific cell surface receptors, other than pro- teoglycans, bind virus but restrict entry (36, 43, ...the human cell ... See full document
9
Herpesvirus Entry Mediator and Nectin-1 Mediate Herpes Simplex Virus 1 Infection of the Murine Cornea
... Herpes simplex virus 1 (HSV-1) is a ubiquitous human pathogen that enters cells by the receptor-mediated fusion of the viral envelope with a host cell ...for ... See full document
7
Herpes simplex virus type 2 infection increases human immunodeficiency virus type 1 entry into human primary macrophages
... of cells physiologically forming a barrier against HIV-1 infection, such as Langherans cells [26], alters the cellular environment at the portal entry and facilitates HIV-1 ... See full document
6
Role of mannose-6-phosphate receptors in herpes simplex virus entry into cells and cell-to-cell transmission.
... involving human pseudo- Hurler fibroblasts, which underphosphorylate cellular and viral glycoproteins, suggest that modification of gD (and perhaps of other viral glycoproteins) with M-6-P is important for the di- ... See full document
12
Herpes Simplex Virus 1 Targets the Murine Olfactory Neuroepithelium for Host Entry
... BHK-21 cells (American Type Culture Collection CCL-10) were propagated in Dulbecco’s modified Eagle’s medium, sup- plemented with 2 mM glutamine, 100 U/ml penicillin, 100 mg/ml strep- tomycin, and 10% fetal calf ... See full document
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