[PDF] Top 20 Heterogeneity of adipose tissue in development and metabolic function

... of adipose triglyceride lipase, hormone-sensitive lipase and monoacylglyceride lipase is higher in human VAT than SAT in the steady state (Arner, 1995; Engfeldt and Amer, 1988) and upon β -adrenergic stimulation ... See full document

... Intra-depot heterogeneity in adipose tissue. A growing body of evidence indicates that adipocytes, even within a single fat pad, are heterogeneous in nature both genetically and metabolically (Figure ... See full document

... some metabolic features of type 2 diabetes, IDM has also been referred to in the literature as atypical diabetes, type ...and metabolic parameters, β-cell pancreatic function and adipose ... See full document

... overall metabolic health of the adipose ...ABCA1 function in adipose tissue has not been analyzed from this perspective, it is potentially of interest to explore the interplay with ... See full document

... Adipose tissue produces adipokines, hormones and cyto- kines and contains various cells, such as adipocytes, preadi- pocytes, vascular cells, endotheliocytes, lymphocytes and macrophages expressing CD14 ... See full document

... Adipose tissue is a connective tissue specified for energy metabolism and endocrines, but func- tional differences between subcutaneous adipose tissue (SAT) and visceral adipose ... See full document

... a function of fat ...into adipose tissue (15, ...a function of fat ...in adipose tissue of these ...transgenic adipose tissue with respect to the degree of ...of  ... See full document

... inal adipose tissue and IR, pancreatic β-cell function, fast- ing glucose, and T2DM were analyzed in eight studies of populations with different ethnic backgrounds ...abdominal adipose ... See full document

... Exosomes function as signaling ...that adipose-derived circulating microRNAs in exosomes regulate important metabolic gene expression in distant tissues such as liver ...from adipose ... See full document

... The formidable interest in BAT is from the hope that it is probably thought to be the panacea for obesity, given the energy expending, glucose and lipid clearance properties (Orava et al 2013 168 , Bartelt et al 2011 242 ... See full document

... the metabolic syndrome ...between adipose tissue deposition and respiratory function ...subcutaneous adipose tissue support abdominal obesity as a causal factor mediating the ... See full document

... of development of insulin resistance in obesity observed in females is cur- rently unknown but could potentially include a change in cortisol ...HPA function, whereas T has the opposite effect ... See full document

... fat tissue and pancreas in ovariectomized ...insulin.Adipose tissue was excised, weighed and used to evaluate the morphology and ...intra-abdominal adipose tissue and the total body fat were ... See full document

... and it has been shown that inhibition of PDC moves the source of energy production from glucose to fatty acids [31]. PDC is composed of three subunits: E1, E2 and E3. Subunit E1 is composed of pyruvate dehydrogenase E1 ... See full document

... Adipose tissue is the only tissue that is able to change its mass substantially even after it reaches the adult size (Spiegelman and Flier, 1996; Hausman et ...of adipose tissue is ... See full document

... in adipose tissue (Curat et ...alter adipose cells function, inducing inflammatory responses, reducing insulin sensitivity and impairing differentiation capability which may contribute to ... See full document

... in adipose tissue and secreted from mature adipocytes (Engeli, Stefan et ...the development of hypertension (Harte, et al, ...of adipose specific AGT contributes to as much as a 30% increase ... See full document

... a metabolic regulator and feedback signal of body fat to regulate appetite, and adiponectin, an insulin- sensitizing and anti-inflammatory ...vivo adipose tissue cultures ...adipocyte function ... See full document

... each metabolic risk factor, such as obesity, fasting plasma glucose, total cholesterol, TG, and hyperuricemia, did not differ from that of subjects with normal ALT levels ... See full document

... proper function of adipose tissue such as adipocyte maturation, lipid storage, formation and maintenance of lipid droplets, membrane composition, DNA repair efficiency, and insulin signaling ... See full document