[PDF] Top 20 Higher affinity oligosaccharide ligands for E selectin
Has 10000 "Higher affinity oligosaccharide ligands for E selectin" found on our website. Below are the top 20 most common "Higher affinity oligosaccharide ligands for E selectin".
Higher affinity oligosaccharide ligands for E selectin
... with E-selectin-Ig, P-selectin-Ig binding to immobilized BSA-sLea was blocked modestly by most oligosaccharides at 1 mM, with no substantial differences among ... See full document
11
Stable Affinity Ligands from Hyperthermophilic Scaffolds: Applications to Macromolecular Purification.
... 31 samples only a very small fraction of the sequence space generated by randomizing a scaffold protein. This is particularly true in case of yeast surface display, where the library sizes range from 10 7 – 10 9 mutants; ... See full document
161
Selectin ligands: will the real ones please stand up?
... high affinity ligands in ...to E-selectin) at a site distinct from the carbohydrate-bind- ing site ...of ligands and a calcium-independent anion-bind- ing site that serves to stabilize ... See full document
6
P selectin is a host receptor for Plasmodium MSP7 ligands
... Plasmodium ligands for P-selectin, the entire ectodomains of 17 ...low affinity extracellular interactions and works by detecting direct binding events within libraries of recombinant proteins ... See full document
9
Design, Selection, and Development of Novel Peptide Ligands for Bioseparations and Diagnostics.
... an affinity and specificity similar to those of biological protein ...to higher levels of molecular complexity, and thus affinity, specificity, and stability, at lower synthesis ...effective ... See full document
419
In Silico Evaluation of Anti Malarial Agents from Hoslundia opposita as Inhibitors of Plasmodium falciparum Lactate Dehydrogenase (PfLDH) Enzyme
... In the absence of the cofactor all ligands showed higher affinity than NADH, and were bound to the cofactors binding site Site A.. When docked in the presence of the cofactor, site B was[r] ... See full document
10
Functional and Structural Characterization of P[19] Rotavirus VP8* Interaction with Histo-blood Group Antigens
... with ligands showed a lack of interac- tions or steric hindrance with the ligands, which may provide a structural basis for the lack of binding to the oligosaccharides in the enzyme immunoassay ... See full document
8
Affinity Adsorption of Viruses Using Small Peptide Ligands
... Different starting materials were examined for their ability to produce pure PPV on the gel filtration column. Both cell culture supernatant and CsCl gradient purified virus, either radioactive or non-radioactive, were ... See full document
294
Affinity Chromatographic Purification of Human Immunoglobulins by Hexamer Peptide Ligands.
... all human IgG (hIgG) subclasses as well as IgGs from bovine, mouse, goat and rabbit. After direct synthesis on Toyopearl AF Amino 650M resins, HWRGWV was able to purify hIgG from complete mammalian cell culture medium ... See full document
230
Engineering Multivalent Protein Affinity Ligands using the Sso7d Scaffold.
... two ligands can bind the epitope and the second 23CTL serves no ...apparent affinity of 23CTL within the tandem homodimer is much higher than when the ligand is expressed by ...T2 affinity for ... See full document
165
Scoring Functions and Modeling of Structure-Activity Relationships for Cannabinoid Receptors
... cannabinoid ligands using the results of docking performed by genetic algorithm software GOLD ...ing affinity between ligand and receptor using scoring ...binding affinity between investigated ... See full document
7
Neutrophils use both shared and distinct mechanisms to adhere to selectins under static and flow conditions
... selectin under flow. These data suggest that PSGL-1 functions cooperatively with L-selectin to mediate optimal attachment of flowing neutrophils to E-selectin but not to P-selectin. ... See full document
11
Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents
... glycoprotein ligands. L-selectin also recognizes endothelial proteoglycans in a calcium-dependent manner, via heparan sulfate (HS) glycosaminoglycan chains enriched in unsubstituted glu- cosamine ...not ... See full document
14
4-aroylpiperidines and 4-(α-hydroxyphenyl)piperidines as selective sigma-1 receptor ligands: synthesis, preliminary pharmacological evaluation and computational studies
... high affinity for typical neuroleptic drugs, such as haloperidol, and their poten‑ tial as alternative targets for antipsychotic ...functional ligands (agonists) for σ receptors by chemical ... See full document
15
Soluble E-Selectin, Soluble L-Selectin and Soluble ICAM-1 in Bronchopulmonary Dysplasia, and Changes With Dexamethasone
... Measurement of plasma concentration of sE-selectin, sL-selec- tin, and sICAM-1 was conducted by quantitative sandwich en- zyme immunoassay kits (R& D Systems, Minneapolis, MN). This method uses a micro plate ... See full document
10
Biomarkers of oxidant stress, insulin sensitivity and endothelial activation in rheumatoid arthritis: a cross sectional study of their association with accelerated atherosclerosis
... Spearman correlations between biomarkers and cardio- vascular risk factors for controls and RA patients are shown in Table 4. In the RA group, urinary 8-IP correlated positively with age and smoking as well as with 10 ... See full document
7
Fenofibrate improves endothelial function and plasma myeloperoxidase in patients with type 2 diabetes mellitus: an open-label interventional study
... in E selectin, suggesting that changes in FMD and E selectin were independent from changes in MPO levels and could be directly attributed to fenofi- brate ... See full document
8
The role of the intestinal microvasculature in inflammatory bowel disease: studies with a modified Caco-2 model including endothelial cells resembling the intestinal barrier in vitro
... was higher compared to the Caco-2 ...even higher apical and basolateral sICAM-1 release compared to Ba/Gd ...as E-selectin, as was observed in the barrier model presented in this ... See full document
12
Synthesis of Amphibian Alkaloids and Synthesis and Affinity of Novel Cannabinoid Receptor Ligands
... Keywords: amphibian alkaloids, enantioselective synthesis, pyrrolidine, cannabinoid receptor,.. marijuana...[r] ... See full document
127
Metal complexes as "protein surface mimetics"
... bind preferentially to the unfolded state of the protein resulted in an acceleration of the rate of tryptic proteolysis. This was first shown to occur in the presence of stoichiometric quantities of porphyrin and then ... See full document
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