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[PDF] Top 20 Human Parvovirus B19 Utilizes Cellular DNA Replication Machinery for Viral DNA Replication

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Human Parvovirus B19 Utilizes Cellular DNA Replication Machinery for Viral DNA Replication

Human Parvovirus B19 Utilizes Cellular DNA Replication Machinery for Viral DNA Replication

... ABSTRACT Human parvovirus B19 (B19V) infection of human erythroid progenitor cells (EPCs) induces a DNA damage response and cell cycle arrest at late S phase, which facilitates ... See full document

16

A novel cellular site-specific DNA-binding protein cooperates with the viral NS1 polypeptide to initiate parvovirus DNA replication.

A novel cellular site-specific DNA-binding protein cooperates with the viral NS1 polypeptide to initiate parvovirus DNA replication.

... 9 replication origins in all these viruses and thus that PIF is likely to be expressed in a wide variety of cell types in many mammalian ...these viral genomes, the requirement for an addi- tional ... See full document

12

Human Parvovirus B19 DNA Replication Induces a DNA Damage Response That Is Dispensable for Cell Cycle Arrest at Phase G2/M

Human Parvovirus B19 DNA Replication Induces a DNA Damage Response That Is Dispensable for Cell Cycle Arrest at Phase G2/M

... how replication of the ssDNA genome of autonomous parvovirus induces a DDR during virus ...exploit cellular components/mechanisms to aid viral ge- nome replication (12, ...B19V ... See full document

11

Human Parvovirus B19 Infection Causes Cell Cycle Arrest of Human Erythroid Progenitors at Late S Phase That Favors Viral DNA Replication

Human Parvovirus B19 Infection Causes Cell Cycle Arrest of Human Erythroid Progenitors at Late S Phase That Favors Viral DNA Replication

... both cellular DNA replication and nuclear DNA ...N DNA content, B19V-infected 4 N cells still incorporated BrdU, indicating active DNA ...by viral DNA ... See full document

10

Recruitment of Brd4 to the Human Papillomavirus Type 16 DNA Replication Complex Is Essential for Replication of Viral DNA

Recruitment of Brd4 to the Human Papillomavirus Type 16 DNA Replication Complex Is Essential for Replication of Viral DNA

... the cellular replication factors—RPA70, RFC1, and DNA poly- merase ...Ori DNA replication in ...HPV16 viral DNA replication, since protein lysates from Brd4 ... See full document

14

The 11-Kilodalton Nonstructural Protein of Human Parvovirus B19 Facilitates Viral DNA Replication by Interacting with Grb2 through Its Proline-Rich Motifs

The 11-Kilodalton Nonstructural Protein of Human Parvovirus B19 Facilitates Viral DNA Replication by Interacting with Grb2 through Its Proline-Rich Motifs

... IMPORTANCE Human parvovirus B19 (B19V) infection causes hematological disor- ders and is the leading cause of nonimmunological fetal hydrops during ...in viral DNA ...B19V DNA ... See full document

15

RNA Binding Protein RBM38 Regulates Expression of the 11-Kilodalton Protein of Parvovirus B19, Which Facilitates Viral DNA Replication

RNA Binding Protein RBM38 Regulates Expression of the 11-Kilodalton Protein of Parvovirus B19, Which Facilitates Viral DNA Replication

... vivo-expanded human erythroid progenitor cells (EPCs) ...of viral mRNA transcripts encoding the 11-kDa ...virus DNA replication and, thereafter, virion ...B19V DNA replication ... See full document

17

Human Papillomavirus DNA Replication Compartments in a Transient DNA Replication System

Human Papillomavirus DNA Replication Compartments in a Transient DNA Replication System

... host replication machinery in the viral replication ...host replication sites at a certain stage(s) of the cell ...host DNA replication is largely completed and the number ... See full document

9

Temporal order of evolution of DNA replication systems inferred by comparison of cellular and viral DNA polymerases

Temporal order of evolution of DNA replication systems inferred by comparison of cellular and viral DNA polymerases

... different DNA replication systems, drawing argument from the differences in their representation among viruses and other selfish replicating ...the DNA replication systems of viruses infecting ... See full document

18

Human Papillomaviruses Recruit Cellular DNA Repair and Homologous Recombination Factors to Viral Replication Centers

Human Papillomaviruses Recruit Cellular DNA Repair and Homologous Recombination Factors to Viral Replication Centers

... ATM DNA damage pathway colocalize with HPV genomes in foci that also contain cellular replication and homologous recombination re- pair ...to viral DNA by chromatin immunoprecipitation ... See full document

7

Roles of E4orf6 and VA I RNA in Adenovirus-Mediated Stimulation of Human Parvovirus B19 DNA Replication and Structural Gene Expression

Roles of E4orf6 and VA I RNA in Adenovirus-Mediated Stimulation of Human Parvovirus B19 DNA Replication and Structural Gene Expression

... cells, human parvovirus B19 (B19V) has recently been shown to repli- cate and form infectious progeny virus in 293 cells in the presence of early adenoviral functions provided either by infection ... See full document

11

Cellular factors required for papillomavirus DNA replication.

Cellular factors required for papillomavirus DNA replication.

... vitro replication of papillomavirus DNA has been carried out with a combination of purified proteins and partially purified extracts made from human ...cells. DNA synthesis requires the ... See full document

11

Molecular biology of giant viruses' DNA replication machinery

Molecular biology of giant viruses' DNA replication machinery

... its replication mechanism and biosynthesis machinery in a way that the virus requires, so instead of producing cellular proteins it will produce more ...the viral genetic information, a fact ... See full document

248

Human parvovirus PARV4 DNA in tissues from adult individuals: a comparison with human parvovirus B19 (B19V)

Human parvovirus PARV4 DNA in tissues from adult individuals: a comparison with human parvovirus B19 (B19V)

... B19V DNA detection was carried out in various tissues of individuals without suspect of acute viral infection, by a real time PCR and a nested PCR, targeting the ORF2 and the ORF1 ...PARV4 DNA was ... See full document

5

Low-Resolution Structure of Vaccinia Virus DNA Replication Machinery

Low-Resolution Structure of Vaccinia Virus DNA Replication Machinery

... marked human history and was eradicated in 1979 thanks to a worldwide mass vaccination ...The viral genome replication machinery appears to be an ideal target, although very little is known ... See full document

11

Expression of human cytomegalovirus UL36 and UL37 genes is required for viral DNA replication.

Expression of human cytomegalovirus UL36 and UL37 genes is required for viral DNA replication.

... inhibit cellular and viral gene expression, and in some of these cases a decrease in the steady-state level of targeted mRNA has been reported (8, 15, ...various viral and nonviral targets have been ... See full document

7

Human mitochondrial DNA replication machinery and disease.

Human mitochondrial DNA replication machinery and disease.

... Many unresolved issues exist in our understanding of mitochondrial syndromes. POLG disorders are especially polymorphic and the question remains as to why some organs and tissues affected in mitochondrial disease and not ... See full document

29

Independent mutations in Ad2ts111 cause degradation of cellular DNA and defective viral DNA replication.

Independent mutations in Ad2ts111 cause degradation of cellular DNA and defective viral DNA replication.

... Soluble nuclear extracts prepared from Ad2tslll-infected HeLa cells grown at either the permissive (32°C) or the nonpermissive (39.5°C) tempera- ture are thermolabile for elongation but [r] ... See full document

8

Multiplication of parvovirus LuIII in a synchronized culture system. III. Replication of viral DNA.

Multiplication of parvovirus LuIII in a synchronized culture system. III. Replication of viral DNA.

... Moreover, gradient sedimentation and electron microscopy of DNA extracted from infected cells at the height of synthesis of progeny viral DNA revealed the presence of at least one additi[r] ... See full document

13

DNA polymerase requirements for parvovirus H-1 DNA replication in vitro.

DNA polymerase requirements for parvovirus H-1 DNA replication in vitro.

... We have recently demonstrated the ability of purified polymerase -y to carry out the synthesis in vitro of RF from single-stranded viral DNA (1Sa), a reaction quite similar or identical [r] ... See full document

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