[PDF] Top 20 The use of ICS/LABA (extra-fine and non-extra-fine) in elderly asthmatics
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The use of ICS/LABA (extra-fine and non-extra-fine) in elderly asthmatics
... in elderly asthmatics are ...the elderly. In the elderly, the ICS/LABA combinations may carry an increased risk of local indesiderable effects, primarily due to the lack of ... See full document
10
<p>Trends in prescriptions and costs of inhaled medications in chronic obstructive pulmonary disease: a 19-year population-based study from Canada</p>
... medication use. For example, a change from an average use of four canisters of medication in 1 year to 5 canisters in the next year would represent a 25% relative year-by-year ...Columbia, ICS, SABA, ... See full document
11
Prescribing of long-acting beta-2-agonists/inhaled corticosteroids after the SMART trial
... in LABA- and ICS-related prescription behaviour after the SMART ...for ICS a slight decrease of ...of LABA/ICS a distinct increase of ...of LABA- and ICS-prescribing in ... See full document
10
Triple therapy (ICS/LABA/LAMA) in COPD: time for a reappraisal
... on ICS preparations were excluded, thereby biasing the selection to patients with poor response to ICS, who were thus likely to fail ICS maintenance ...of ICS-related side effects, led to the ... See full document
11
Efficacy and safety of ipratropium bromide/albuterol compared with albuterol in patients with moderate-to-severe asthma: a randomized controlled trial
... (ICS, LABA, leukotriene modifier, theophylline, anti IgE, oral ...to use open-label ALB-HFA in addition to the blinded study medication if ... See full document
15
LABA/LAMA combinations versus LAMA monotherapy or LABA/ICS in COPD: a systematic review and meta-analysis
... (N=20,185). LABA/LAMA significantly improved trough forced expiratory volume in 1 second (FEV 1 ) from baseline to week 12 versus both LAMA and LABA/ICS ...respectively). LABA/LAMA improved ... See full document
16
<p>Inhaled Corticosteroid Treatment Regimens and Health Outcomes in a UK COPD Population Study</p>
... the LABA-ICS trea- ted patients was marginally lower, the con fi dence intervals crossed those treated with triple therapy; it is possible a larger sample size would fi nd the effect estimate not to be ... See full document
10
The effect of budesonide/formoterol maintenance and reliever therapy on the risk of severe asthma exacerbations following episodes of high reliever use: an exploratory analysis of two randomised, controlled studies with comparisons to standard therapy
... budesonide/formoterol use, there was a further reduced incidence of exacerba- tions including asthma-related SAEs and DAEs com- pared with the larger groups using LABA or SABA as ...using ICS or ... See full document
11
Asthma
... with ICS ther- apy. The combination of a LABA and ICS has been shown to be highly effective in reducing asthma symp- toms and exacerbations, and is the preferred treatment option in adolescents or ... See full document
9
Maintenance therapy in COPD: time to phase out ICS and switch to the new LAMA/LABA inhalers?
... the use of inhaled corticosteroids (ICS). The new LAMA/LABA inhalers could potentially reduce the use of ICS as part and parcel of maintenance therapy in ...with ICS/LABA ... See full document
6
Step-down therapy in well-controlled asthmatic patients using salmeterol xinafoate/fluticasone propionate combination therapy
... of LABA in the FP step-down therapeutic protocol caused a gradual decrease in %FEF 50 , reaching 90% of baseline values after 12 ...continuous use of low-dose LABA with low-dose ICS may ... See full document
6
Trend of cost and utilization of COPD medication in Korea
... the use of more than one of the following COPD medications at least twice per year: long-acting muscarinic antagonist (LAMA), long-acting beta-2 agonist (LABA), inhaled corticosteroid (ICS) + ... See full document
7
Dose-response relationship of ICS/fast-onset LABA as reliever therapy in asthma
... Severe exacerbations as defined by the ATS/ERS were the primary outcome variable used to assess potency and efficacy in this paper [8]. This is because severe ex- acerbations are generally regarded as a crucial asthma ... See full document
8
Day-time variation of serum periostin in asthmatic adults treated with ICS/LABA and adults without asthma
... The use of LABA therapy prior to the baseline morning measurements and no subse- quent medication use during the period of the study, is unlikely to have influenced the periostin or FeNO levels, but ... See full document
10
<p>A Delphi Consensus Document on the Use of Single-Inhaler Fixed-Dose Triple Therapies in COPD Patients</p>
... of LABA/LAMA and ...dual LABA/ICS therapy, it is possibly due to the differences in ef fi cacy and safety Table 5 Results of the Degree of Agreement Among the Panelists with the Statements Regarding ... See full document
11
Asthma
... with ICS therapy. The combination of a LABA and ICS has been shown to be highly effective in reducing asthma symptoms and exacerbations, and is the preferred treatment option in adolescents or adults ... See full document
16
A Systematic Review of Long-Acting β2-Agonists Versus Higher Doses of Inhaled Corticosteroids in Asthma
... tween ICS+LABA and double doses of ICS in reducing the incidence of asth- ma exacerbations requiring systemic corticosteroids but it did decrease the risk comparing to higher than double doses of ... See full document
10
Early achievement and maintenance of stable asthma control using initially higher-dose inhaled corticosteroids as part of combination therapy: an open-label pilot study
... -agonist use, and frequency of exacerbations, using daily fluticasone doses of 200–500 µ ...of ICS being used in the long ...using ICS doses higher than 500 µ g/day and did not combine with ... See full document
8
The evidence on tiotropium bromide in asthma: from the rationale to the bedside
... which LABA in association with inhaled corticosteroids (ICS) at low doses were added beginning from step 3, to be increased in step 4 and 5 [27, ...increased use of oral corticosteroids and rescue ... See full document
18
Early efficacy of budesonide/formoterol in patients with moderate-to-very-severe COPD
... the ICS/LABA combination in COPD patients who had experienced at least one exacerbation in the past ...lower use of reliever medication, and fewer ... See full document
13
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