[PDF] Top 20 Identification and Characterization of Genes That Interact With lin-12 in Caenorhabditis elegans
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Identification and Characterization of Genes That Interact With lin-12 in Caenorhabditis elegans
... sup1 7 locus, we were able to test the cause of this semi- to suppression.. We conclude that the weak semidomi- nance of sup-l 7 mutations is caused by reduced gene [r] ... See full document
21
Identification and Characterization of Autosomal Genes That Interact With glass in the Developing Drosophila Eye
... hairy gene function in the Drosophila eye: normal expression is dispensable but ectopic expression alters cell fates. CARROLL, 1995 Hairy and Emc negatively regulate morpho[r] ... See full document
15
Suppressors of a lin-12 hypomorph define genes that interact with both lin-12 and glp-1 in Caenorhabditis elegans.
... These sel genes appear to interact with lin-12 in multiple cell fate decisions since the sel mutations each suppress several different defects associated with reduced [r] ... See full document
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IDENTIFICATION AND CHARACTERIZATION OF 22 GENES THAT AFFECT THE VULVAL CELL LINEAGES OF THE NEMATODE CAENORHABDITIS ELEGANS
... In determining the penetrance of the Vu1 phenotype resulting from these two mutations (as in determining the penetrance of the two alleles of lin-24; see above), we me[r] ... See full document
56
A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of Caenorhabditis elegans
... The Caenorhabditis elegans pRb ortholog, LIN-35, functions in a wide range of cellular and developmental ...of LIN-35 in nutrient utilization by the intestine, which it carries out redundantly ... See full document
27
sel-7, a Positive Regulator of lin-12 Activity, Encodes a Novel Nuclear Protein in Caenorhabditis elegans
... lag-1, lin-12(intra), sel-7, sel-8, for its ...15, 12 regrew on SC-Leu-Trp and Not I sites or between SalI and Spe I sites on both plasmids plates; these 12 colonies represented three ... See full document
10
SEL-5, A Serine/Threonine Kinase That Facilitates lin-12 Activity in Caenorhabditis elegans
... several genes and to interact with some others (re- difference is that the unaffected cells are epithelial cells viewed by Ko and Prives 1996; Levine 1997), including with a well-defined apical/basolateral ... See full document
14
Identification of Genes That Regulate a Left-Right Asymmetric Neuronal Migration in Caenorhabditis elegans
... C. elegans, cells of the QL and QR neuroblast lineages migrate with left-right asymmetry; QL and its descendants migrate posteriorly whereas QR and its descendants migrate ...identify genes involved in ... See full document
14
New Genes That Interact With lin-35 Rb to Negatively Regulate the let-60 ras Pathway in Caenorhabditis elegans
... synMuv genes, lin-35, is a member of the retinoblastoma identification and characterization of numerous genes (Rb) gene family; one member of this family, Rb, acts as involved in ... See full document
18
Characterization of Seven Genes Affecting Caenorhabditis elegans Hindgut Development
... characterized 12 mutations in seven genes that affect the development of the Caenorhabditis elegans ...the genes also affect ...the genes fall into four distinct classes: (1) ... See full document
12
Null Mutations in the lin-31 Gene Indicate Two Functions During Caenorhabditis elegans Vulval Development
... The lin-31 gene is required for the proper specification of vulval cell fates in the nematode Caenorhabditis elegans and encodes a member of the winged-helix family of transcription ...13 ... See full document
8
Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14.
... T h e intragenic recombinant strain was expected to carry the Bergerac allele of any RFLP detected with a clone from the contig mapping to the left of the lin-14 intrageni[r] ... See full document
16
Identification of Heterochronic Mutants in Caenorhabditis elegans: Temporal Misexpression of a Collagen::Green Fluorescent Protein Fusion Gene
... of lin-42 ...stage lin-42(ve16) ...stage lin-42(ve20) hermaphrodite stained with the antibody ...stage lin-42(ve20) showing precocious col-19::gfp expres- ... See full document
17
LIN 12/Notch trafficking and regulation of DSL ligand activity during vulval induction in Caenorhabditis elegans
... of LIN-12 in all VPCs, suggesting that at least some of these serine/threonine residues are likely to be constitutively phosphorylated to promote basal ...of LIN-12 from the apical plasma ... See full document
12
Suppressors, Screens, and Genes: An Educational Primer for Use with “A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of Caenorhabditis elegans”
... the lin-35; slr-2 double-mutant worms die before they can ma- ture and produce offspring, how does one collect double- mutant worms that have ingested the RNAi-inducing bacte- ria and that can produce offspring ... See full document
5
An Evolutionarily Conserved Pathway Essential for Orsay Virus Infection of Caenorhabditis elegans
... C. elegans intestinal cells (5) and leads to morphological disrup- tions of the intestine ...two genes, sid-3, a nonreceptor tyrosine kinase, and ...C. elegans ortholog of human Wiskott-Aldrich ... See full document
16
Caenorhabditis elegans lin-13, a Member of the LIN-35 Rb Class of Genes Involved in Vulval Development, Encodes a Protein With Zinc Fingers and an LXCXE Motif
... eliminate lin-13 ...specification, lin-13 activity appears to be necessary of lin-13 is likely to be zygotic ...with lin-13(n387) and lin-13(n388), we found vulva phenotype observed at ... See full document
11
EGF, WNT & HOX Interactions during Patterning of Caenorhabditis elegans Equivalence Groups
... Comparing the VPCs, HCG, P11/12 and γ / δ equivalence groups allows us to identify several similarities and differences that may explain how the same signaling pathways specify different fates in different ... See full document
187
A Stomatin and a Degenerin Interact to Control Anesthetic Sensitivity in Caenorhabditis elegans
... Because stomatin-like proteins are thought to interact with sodium channels, any ENaCs that are expressed in the same cells as UNC-1 are potentially important in the function of UNC-1. UNC-8 is expressed in a ... See full document
10
Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans.
... Caenorhabditis elegans: ced-1, ced-2 and nuc-I. Electron microscopic studies reveal that mutations in each of these genes prevent engulfment, indicating that these genes[r] ... See full document
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