[PDF] Top 20 Identification of the hepatitis B virus factor that inhibits expression of the beta interferon gene.
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Identification of the hepatitis B virus factor that inhibits expression of the beta interferon gene.
... The chloramphenicol acetyltransferase CAT-containing plasmids that were used in this study were i pTWU54, in which the cat gene is under the control of the 353-bp HindIll-HincIl DNA regi[r] ... See full document
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Identification of the Rabies Virus Alpha/Beta Interferon Antagonist: Phosphoprotein P Interferes with Phosphorylation of Interferon Regulatory Factor 3
... The identification of proteins from negative-strand RNA viruses that interfere with IRF-3 activa- tion is therefore not ...for virus replication and which have “luxury functions” (34) are active as IFN an- ... See full document
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Hepatitis A Virus 3C Protease Cleaves NEMO To Impair Induction of Beta Interferon
... acid-inducible gene I (RIG-I)-like receptors (RLRs), primarily melanoma differentiation-associated protein 5 (MDA5) (2–4) and sometimes RIG-I (5), and by Toll-like re- ceptor 3 (TLR3) (6, ...feron beta ... See full document
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Tumor necrosis factor alpha negatively regulates hepatitis B virus gene expression in transgenic mice.
... These classes of inflammatory cells produce an assortment of cytokines, such as tumor necrosis factor alpha TNF-a, alpha interferon IFN-ot, gamma interferon IFN-y, interleukin-1 alpha IL[r] ... See full document
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Hepatitis E Virus Inhibits Type I Interferon Induction by ORF1 Products
... E virus (HEV) causes both endemic and epidemic human hepatitis by fecal-oral transmission in many parts of the ...poly(I·C)-induced beta interferon (IFN-) expression and that the HEV ... See full document
9
Recombinant Duck Interferon Gamma Inhibits Duck Hepatitis B Virus Replication in Primary Hepatocytes
... human hepatitis B virus (HBV), the woodchuck hepatitis virus (WHV), and the duck hepatitis B virus ...that interferon gamma (IFN-g) and tumor necrosis ... See full document
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Intrahepatic Induction of Alpha/Beta Interferon Eliminates Viral RNA-Containing Capsids in Hepatitis B Virus Transgenic Mice
... ectromelia virus and vaccinia virus as well as herpes simplex virus (HSV) by inducing nitric oxide synthase ...vaccinia virus repli- cation by inducible nitric oxide synthase occurs during ... See full document
9
Gene Expression Profiling of the Cellular Transcriptional Network Regulated by Alpha/Beta Interferon and Its Partial Attenuation by the Hepatitis C Virus Nonstructural 5A Protein
... the expression of multiple genes that encode for calcium-binding proteins, or which function in a calcium-dependent manner, was altered in response to NS5A ...NS5A expression resulted in the activation of a ... See full document
9
Identification and characterization of interferon signaling-related microRNAs in occult hepatitis B virus infection
... Occult hepatitis B virus infection (OBI) is an important risk factor of liver cirrhosis and hepatocellular ...1 interferon (IFN) signaling-related miRNAs were significantly associated ... See full document
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The Interferon-Inducible Protein Tetherin Inhibits Hepatitis B Virus Virion Secretion
... I interferon (interferon alpha/beta [IFN- ␣ /  ]) is a broad- spectrum antiviral agent that plays a pivotal role in the innate defense against viral ...to virus infection ...the virus ... See full document
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Inhibition of Alpha Interferon Signaling by Hepatitis B Virus
... that hepatitis C virus, a member of the Flaviviridae family, induces the upregulation of PP2Ac in vivo (liver biopsy studies of HCV transgenic mice) and in vitro (tetracycline-regulated HCV protein ... See full document
7
Regulation of transforming growth factor beta 1 expression by the hepatitis B virus (HBV) X transactivator Role in HBV pathogenesis
... A GAL4-Egr-1 fusion protein can mediate transcription ac- tivation by HBx. To confirm that the Egr-1 protein was directly involved in HBx-mediated transcriptional activation of TGF- b1, we designed a protein fusion ... See full document
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Transcription of the human beta interferon gene is inhibited by hepatitis B virus.
... Other plasmids used in this study were pTWU54, containing the cat structural gene that is controlled by the 353-bp regulatory elements involved in the expression of the human beta interf[r] ... See full document
7
Human Cytomegalovirus Immediate-Early 2 Gene Expression Blocks Virus-Induced Beta Interferon Production
... Ebola virus VP35 protein and the hepatitis C virus NS3/4A protease interfere with the phosphorylation of IRF-3 and therefore block its ability to translocate to the nucleus and activate transcription ... See full document
5
Inhibition of Hepatitis B Virus Gene Expression and Replication by Hepatocyte Nuclear Factor 6
... By using the pSV40-HBV and pCMV-HBV constructs, the HNF6-mediated HBV pgRNA inhibition was shown to be inde- pendent of the nature of the HBV promoters (Fig. 6). Therefore, it is likely that HNF6 might influence the ... See full document
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Interleukin-2 and alpha/beta interferon down-regulate hepatitis B virus gene expression in vivo by tumor necrosis factor-dependent and -independent pathways.
... 1265 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest We have recently reported that administration of recombinant tumor necrosis factor alpha TNF-a to hepatitis B virus [r] ... See full document
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Steroid receptor coactivator 3 inhibits hepatitis B virus gene expression through activating Akt signaling to prevent HNF4α nuclear translocation
... enforced expression of SRC-3 in SRC-3-knockdown HepG2 cells reduced the levels of HBV mRNA and HBV proteins HBsAg and ...Ectopic expression of constitutively activated Akt impaired the enhancement of HBV ... See full document
9
Hepatitis B Virus Regulatory HBx Protein Binds to Adaptor Protein IPS-1 and Inhibits the Activation of Beta Interferon
... In summary, our study provides evidence that the HBV regulatory protein HBx interferes with the activation of the innate immune response. The strengths of this study include the fact that HBx binding partners were ... See full document
9
Inhibition of the Alpha/Beta Interferon Response by Mouse Hepatitis Virus at Multiple Levels
... the expression of one IFN-  gene and several IFN- ␣ genes, represents one of the first lines of defense against viral infection ...ducible gene I (RIG-I) (14, 30, 79) and Mda5 (melanoma ... See full document
11
RIG-I Signaling Is Essential for Influenza B Virus-Induced Rapid Interferon Gene Expression
... influenza B virus activates IRF3 at 1 h postinfection in a RIG-I-dependent manner, which means that RIG-I must sense the incoming vRNA ...A virus nucleo- capsids were recognized by RIG-I, the ... See full document
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