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[PDF] Top 20 Identification of Long-Range Regulatory Elements in the Human Genome

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Identification of Long-Range Regulatory Elements in the Human Genome

Identification of Long-Range Regulatory Elements in the Human Genome

... enhancer elements as well as their target genes simultaneously by detecting two linearly independent DNA segments that are bound to one another via a protein ...promoter elements to allow design of specific ... See full document

141

Identification of Restriction Factors by Human Genome Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L−C7L− Mutant

Identification of Restriction Factors by Human Genome Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L−C7L− Mutant

... host range mu- tants that exhibit impaired replication in nonpermissive ...in human cells at a step prior to late gene expression, was chosen for this ...a human genome-wide small interfering ... See full document

10

Identification of cis-regulatory sequence variations in individual genome sequences

Identification of cis-regulatory sequence variations in individual genome sequences

... the human genome, the gene promoter(s) that each acts on, the biological condition(s) under which each TFBS is active and the TF(s) that interact with ...broad range of TFBS data, using a convenient ... See full document

14

Mobile elements in the human genome: implications for disease

Mobile elements in the human genome: implications for disease

... characterize genome sequences of scarce samples or even single ...polymorphic human-specific L1 (L1Hs) retrotransposi tion events has been developed by Ewing and Kazazian, comprising hemi- specific PCR ... See full document

8

Understanding the regulatory genome

Understanding the regulatory genome

... of regulatory elements will be located in the vicinity of the gene, taking as limits the neighbouring 5’ and 3’ genes as long as their expression does not show significant overlap with the gene under ... See full document

13

LINE dancing in the human genome: transposable elements and disease

LINE dancing in the human genome: transposable elements and disease

... of human genetic ...as long-range PCR, targeted array comparative genome hybridization (array-CGH) analysis, and multiplex ligation-dependent probe assays ...sporadic human diseases ... See full document

8

Long-Range RNA-RNA Interactions Circularize the Dengue Virus Genome

Long-Range RNA-RNA Interactions Circularize the Dengue Virus Genome

... essential regulatory roles during translation, RNA replication, and assembly of new viral ...the genome have been proposed to be required for RNA ...RNA elements present at the ends of the dengue ... See full document

13

Identification of DNA methylation changes associated with human gastric cancer

Identification of DNA methylation changes associated with human gastric cancer

... scoring genome- wide methylation levels at 50-bp intervals, we first examined the chromosomal methylation patterns of nor- mal ...of long interspersed nuclear elements (LINEs) were relatively low ... See full document

15

Identification and Characterization of Reverse Transcriptase Fragments of Long Interspersed Nuclear Elements (LINEs) in the Morus notabilis Genome

Identification and Characterization of Reverse Transcriptase Fragments of Long Interspersed Nuclear Elements (LINEs) in the Morus notabilis Genome

... berry genome were analyzed in terms of heterogeneity, phylogeny, and chro- mosomal ...these elements were not abundant in the mulberry ...these elements in the subte- lomeric and pericentromeric ... See full document

15

Identification of regulatory elements in the CD8 gene locus.

Identification of regulatory elements in the CD8 gene locus.

... merits of O.Skb and Ikb in size are visible. The hybridisation pattern in the 129SV EcoRI digest shown here also differs to that of a C57B1/ 6 T lym phom a and to that of a C58 derived thymom a cell line as has been ... See full document

340

Krox20 hindbrain cis regulatory landscape: interplay between
multiple long range initiation and autoregulatory elements

Krox20 hindbrain cis regulatory landscape: interplay between multiple long range initiation and autoregulatory elements

... cis-acting elements present within fragments 3 and 5, we divided the chicken genomic region between –100 kb and –28 kb upstream of Krox20 into six fragments (6-11, ...the human ␤ -globin minimal promoter ... See full document

10

Identification and functional characterization of microRNA regulatory elements in Brassicaceae

Identification and functional characterization of microRNA regulatory elements in Brassicaceae

... of long non-coding miRNAs are fundamental, sequence-specific regulatory elements of eukaryotic ...detect regulatory elements in the promoter regions provided a pathway to understand the ... See full document

142

Genome wide Annotation, Identification, and Global Transcriptomic Analysis of Regulatory or Small RNA Gene Expression in Staphylococcus aureus

Genome wide Annotation, Identification, and Global Transcriptomic Analysis of Regulatory or Small RNA Gene Expression in Staphylococcus aureus

... small regulatory or small RNAs (sRNAs) have been identified, yet this class of molecule remains poorly understood and severely ...from genome annotation files, and as a consequence, their existence is often ... See full document

13

Genome wide identification of enhancer elements

Genome wide identification of enhancer elements

... to regulatory elements stabilize a bend in the DNA that enables them to physically contact the basal promoter region (Levine et ...the regulatory elements responsible for transcription (or ... See full document

11

Identification of regulatory elements in the Isl1 gene locus

Identification of regulatory elements in the Isl1 gene locus

... from human, dog, rat, chick, and Xenopus using the Genome Alignment function of the ECR browser (Ovcharenko et ...sequence elements on the 3cF10 sequence when compared to other mammalian ...gene ... See full document

13

Remotely acting SMCHD1 gene regulatory elements: in silico prediction and identification of potential regulatory variants in patients with FSHD

Remotely acting SMCHD1 gene regulatory elements: in silico prediction and identification of potential regulatory variants in patients with FSHD

... direct long-range interactions occur between gene promoters and distal genomic regions, bringing them into close spatial proximity through looping interactions [12], thereby explaining the impact of ... See full document

8

Genome wide identification of regulatory elements in Sertoli cells

Genome wide identification of regulatory elements in Sertoli cells

... In the mouse, male sex determination is initiated around embryonic day 11.5 (E11.5) by expression of the Y-linked gene Sry , which diverts XY supporting cells to the Sertoli cell fate (Fig. 1A). Sry is transiently ... See full document

11

Identification of transcriptional regulatory elements for Ntng1 and Ntng2 genes in mice

Identification of transcriptional regulatory elements for Ntng1 and Ntng2 genes in mice

... rat, human, chimpanzee, rhesus macaque, cow, dog, and chicken (Additional file 4: Figure S2), and contained 17 transcription factor binding sites within the sequences (Additional file 8: Figure ... See full document

16

Identification of an effective siRNA target site and functional regulatory elements, within the hepatitis B virus posttranscriptional regulatory element

Identification of an effective siRNA target site and functional regulatory elements, within the hepatitis B virus posttranscriptional regulatory element

... narrow range of patients and is associated with a number of adverse effects whereas a long-term use of lamivudine and adefovir dipivoxil could cause drug-resistant var- iants of HBV ... See full document

10

Bovine leukemia virus long terminal repeat variability: identification of single nucleotide polymorphisms in regulatory sequences

Bovine leukemia virus long terminal repeat variability: identification of single nucleotide polymorphisms in regulatory sequences

... BLV genome is flanked at both 5′ and 3′ ends by long terminal repeat (LTR) sequences [4, ...eral regulatory elements critical for the modulation of promoter activity ...major regulatory ... See full document

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