[PDF] Top 20 Identification of a novel long non-coding RNA within RUNX1 intron 5
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Identification of a novel long non-coding RNA within RUNX1 intron 5
... described, RUNX1 intron 5 is involved in the generation of the chromosomal trans- location (8;21) in AML patients; therefore, we expected to find an indication of chromatin accessibility along the ... See full document
9
Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing
... protein coding genes or pseudogenes in each tissue type, including in control ...of long non- coding RNA, such as DNA methylation, is particularly sensitive to the carcinogenic ...of ... See full document
16
Identification of novel long non-coding RNAs in triple-negative breast cancer
... of rRNA by using an mRNA-ONLY Eukaryotic mRNA IsolationKit (Epicentre Biotechnologies, USA). Then, each sample was transcribed to double strand cDNA, then synthesized into cRNA and labeled with Cyanine-3-CTP. The labeled ... See full document
10
Identification of long non-coding RNA signatures in triple-negative breast cancer
... Results: A total of 1034 dysregulated lncRNAs were found in the two microarrays, and there were 8 overlapped lncR- NAs. Among them, 537 lncRNAs were significantly correlated with 451 protein-coding genes (PCGs). ... See full document
10
<p><em>SNHG16</em>: A Novel Long-Non Coding RNA in Human Cancers</p>
... a long ncRNA ...transcription. 5 However, studies have shown that lncRNAs can regulate gene expression at the epigenetic, transcrip- tional, and post-transcriptional ... See full document
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Original Article Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer
... total RNA was reversely transcribed to cDNA by using PrimeScript RT-polymerase (Takara, Dalian, ...for 5 s and 60°C for 30 s. PCR with the following primers: XIST, Forward 5’-CTCTCCATTGGGTTCAC-3’ and ... See full document
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<p>Plasma Long Non-Coding RNA RP11-438N5.3 as a Novel Biomarker for Non-Small Cell Lung Cancer</p>
... fugation within two hours post the ...Total RNA was extracted from the plasma samples using Trizol LS Reagent per manufacturer ’ s instructions (Invitrogen, CA, ...the RNA pellets were resuspended in ... See full document
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Unique long non-coding RNA expression signature in ETV6/ RUNX1-driven B-cell precursor acute lymphoblastic leukemia
... Interestingly, coding genes adjacent to some of these lncRNAs showed unique overexpression in ETV6/RUNX1-positive BCP-ALLs, suggesting a possible cis regulatory relationship between these lncRNAs and their ... See full document
12
Identification of long non-coding RNA-related and –coexpressed mRNA biomarkers for hepatocellular carcinoma
... Forty one mRNA biomarkers (Table 1) met our criteria of (1) being differentially expressed between 16 normal and 16 cancer samples with qvalue < 0.05; and 2) being positionally related to lncRNA which were ... See full document
10
Identification of a long non-coding RNA NR_026689 associated with lung carcinogenesis induced by NNK
... a novel lncRNA, POU3F3, in plasma which is a novel biomarker for the diagnosis of esophageal squamous cell carcinoma ...as novel candidate early biomarkers for mouse liver tumor promotion ... See full document
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Expression and clinical significance of long non coding RNA HNF1A AS1 in human gastric cancer
... adjacent non-neoplastic gastric tissues. LncRNA HNF1A antisense RNA 1 (HNF1A- AS1) was one of the LncRNAs that were identified to be downregulated in GC tissues by the microarray ...mately 5 kb ... See full document
7
Identification of a novel human long non-coding RNA that regulates hepatic lipid metabolism by inhibiting SREBP-1c
... dysregulation. Long non-coding RNAs (lncRNAs) have been identified with diverse biological functions, but the effects of lncRNAs on lipid metabolism are rarely ...a novel human specific ... See full document
9
<p>Identification of Potential Prognostic Long Non-Coding RNA Biomarkers for Predicting Recurrence in Patients with Cervical Cancer</p>
... Figure 5 Relative expression of candidate lncRNAs from circlncRNAnet data. (A) The expression of DELs in tumor and adjacent tissues in CC. (B) Expression levels of HCG11 in tumor and adjacent tissues in 20 ... See full document
12
Abstract: Long non-coding RNAs (lncRNAs) are a novel class of regulatory RNA molecules and they
... lncRNA within a chromatin remodeling complex and up-regulate endothelial genes, including SRY (Sex Determining Region Y)-Box 18 (SOX18), mothers against decapentaplegic homologue 6 (SMAD6), and chicken ovalbumin ... See full document
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<p>Latest Advances of Long Non-Coding RNA SNHG5 in Human Cancers</p>
... Meanwhile, there were some overlaps on the role of SNHG5 in particular tumors. For example, miRNA- 32, 13,33 miR-26a-5p 15,30 and miR-363-3p 31,36 were involved in functional processes of SNHG5 in two or more cancers, ... See full document
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ZFAS1: a novel tumor-related long non-coding RNA
... Moreover, identification of small-molecule inhibitors of ZFAS1 through chemical library screening is also necessary to translate findings from basic science into clinical ... See full document
8
Plasma long non-coding RNA BACE1 as a novel biomarker for diagnosis of Alzheimer disease
... to intron 1 of the neuronal sortilin-related receptor gene (SORL1) gene, which had long been hypothesized to be involved in AD pathogenesis ...200 RNA (BC200) is a translational adjustor that targets ... See full document
8
Long non-coding RNA ENST00000457645 reverses cisplatin resistance in CP70 ovarian cancer cells.
... As the development of biochips and sequencing technologies has advanced, it has become apparent that lncRNAs play critical roles in the pathogenesis of multiple diseases (Archer et al., 2015; Kawasaki et al., 2016). ... See full document
10
Long non-coding RNA: a new player in cancer
... other novel lncRNA YIYA is upregulated in different can- cers and promotes cell cycle progression at the G1/S transition, demonstrating it is a carcinogenesis-associated lncRNA ...a novel therapeutic target ... See full document
7
<p>Association Between lncRNA HULC rs7763881 Polymorphism and Gastric Cancer Risk</p>
... rs7763881 AA genotype. Moreover, strati fi cation analysis of Egyptian populations by Shaker et al suggested that rs7763881 AC genotype is signi fi cantly associated with decreased CRC risk in younger patients compared to ... See full document
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