[PDF] Top 20 Immunity to Cryptococcus neoformans and C. gattii during cryptococcosis
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Immunity to Cryptococcus neoformans and C. gattii during cryptococcosis
... DCs appear to be the primary route by which cryptococcal anti- gen is presented to stimulate T cells, although a previous study had suggested that AMs might also be able to stimulate T cells via cryp- tococcal antigen ... See full document
11
Molecular Typing of Clinical and Environmental Cryptococcus neoformans Strains Isolated in Italy
... mostly Cryptococcus neoformans and Cryptococcus gattii have been associated with life-threatening infections in humans and other animals, while infections with other species have rarely been ... See full document
9
Rapid Identification of Cryptococcus neoformans var grubii, C neoformans var neoformans, and C gattii by Use of Rapid Biochemical Tests, Differential Media, and DNA Sequencing
... of Cryptococcus neoformans var. grubii, Cryptococcus neoformans ...var. neoformans, and Cryptococcus gattii is imperative for facilitation of prompt treatment of ... See full document
6
Development of Protective Inflammation and Cell Mediated Immunity against Cryptococcus neoformans after Exposure to Hyphal Mutants
... of Cryptococcus is dependent on Th1- polarized cell-mediated ...expression during Cryptococcus infection ...in Cryptococcus, we decided to focus on the impact of Cryptococcus morphotype ... See full document
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Growth and Pigment Production on d Tryptophan Medium by Cryptococcus gattii, Cryptococcus neoformans, and Candida albicans
... Cryptococcus neoformans was classically subdivided into the three varieties: ...C. neoformans var. gattii (serotypes B and C), ...C. neoformans var. ... See full document
10
Continental Drift and Speciation of the Cryptococcus neoformans and Cryptococcus gattii Species Complexes
... the C. neoformans and C. gattii species complexes are likely to have diverged in the Cretaceous and share so many phenotypes associated with virulence have interesting implications for their ... See full document
6
Cryptococcus gattii in North American Pacific Northwest: Whole Population Genome Analysis Provides Insights into Species Evolution and Dispersal
... ryptococcus gattii, an environmental basidiomycetous yeast and the primary cause of cryptococcosis in immunocompe- tent patients, has been previously primarily associated with cen- tral nervous system ... See full document
18
The Primary Target Organ of Cryptococcus gattii Is Different from That of Cryptococcus neoformans in a Murine Model
... recent cryptococcosis outbreak emerged in Vancouver, Canada, in 1999 ...then, C. gattii has attracted considerable attention as a public health issue, and the number of research articles on ... See full document
9
Identification of Genotypically Diverse Cryptococcus neoformans and Cryptococcus gattii Isolates by Luminex xMAP Technology
... Cryptococcus neoformans and Cryptococcus gattii are closely related pathogenic yeasts, as indicated by the previ- ous description of ...C. gattii as a variety of ...C. ... See full document
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Development of a lateral flow recombinase polymerase amplification assay for rapid and visual detection of Cryptococcus neoformans/C gattii in cerebral spinal fluid
... Early diagnosis and treatment of cryptococcosis reduces mortality. Lumbar puncture, also known as spinal tap, and cerebral spinal fluid (CSF) analysis should be performed in patients with suspected CM [3, 6]. For ... See full document
9
Chloroquine induces human mononuclear phagocytes to inhibit and kill Cryptococcus neoformans by a mechanism independent of iron deprivation
... was protective in animal models, our data lend support for clinical trials evaluating chloroquine for adjunctive treatment and prophylaxis of cryptococcosis. In addition to its once- weekly oral dosage and low ... See full document
8
Cryptococcus neoformans Mates on Pigeon Guano: Implications for the Realized Ecological Niche and Globalization
... decades, C. neoformans infections have in- creased in prevalence as the population of immunocompro- mised individuals expanded due to the AIDS pandemic, ag- gressive cancer therapy, and organ ...human ... See full document
11
Essential Gene Discovery in the Basidiomycete Cryptococcus neoformans for Antifungal Drug Target Prioritization
... In strain 2aPlate4C11, only one T-DNA insertion was identi- fied. The hit gene is CNAG_03105, and it encodes a hypothetical protein with no known conserved domains. This protein shares homology with the S. cerevisiae ... See full document
18
On the Emergence of Cryptococcus gattii in the Pacific Northwest: Ballast Tanks, Tsunamis, and Black Swans
... Water. C. gattii from the PNW has been shown to demonstrate long-term survival (at least 1 year) in ocean water, and immediate environmental studies found multiple positive ocean samples near the Vancouver ... See full document
10
Genome Evolution and Innovation across the Four Major Lineages of Cryptococcus gattii
... Despite these limitations, it is interesting that a subset of genes involved in stress response and metal acquisition in C. neoformans appears to be highly dynamic in terms of loss and gain by each of the ... See full document
12
Divergence of Protein Kinase A Catalytic Subunits in Cryptococcus neoformans and Cryptococcus gattii Illustrates Evolutionary Reconfiguration of a Signaling Cascade
... in Cryptococcus. Prior to the divergence of C. gattii from ...C. neoformans around ...In C. gattii, Pka1 and Pka2 both retain the majority of their original functions, ... See full document
8
Isolation and Characterization of Senescent Cryptococcus neoformans and Implications for Phenotypic Switching and Pathogenesis in Chronic Cryptococcosis
... Cryptococcus neoformans is an encapsulated yeast that causes chronic meningoencephalitis predominantly in patients with advanced human immunodeficiency virus ...models, C. neoformans strain ... See full document
9
A New Lineage of Cryptococcus gattii (VGV) Discovered in the Central Zambezian Miombo Woodlands
... A multisample variant call format (VCF) corresponding to all 101 genomes was made with VCFtools (72) and converted to ped and map file formats for use in PLINK v1.90 (73). Unsupervised ADMIXTURE (74) was run on a ... See full document
19
Cryptococcus neoformans Host Adaptation: Toward Biological Evidence of Dormancy
... ABSTRACT Cryptococcosis is an opportunistic infection due to the ubiquitous yeast Cryptococcus ...primoinfection during childhood, which is followed by dormancy and, in some individuals, reactivation ... See full document
13
Highly Recombinant VGII Cryptococcus gattii Population Develops Clonal Outbreak Clusters through both Sexual Macroevolution and Asexual Microevolution
... in C. neoformans by dramatically increasing the incidence of aneuploidy ...In C. neoformans, serial growth under laboratory con- ditions or in animals can lead to attenuation (10) or elevation ... See full document
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