[PDF] Top 20 Immunotyping of Human Immunodeficiency Virus Type 1 (HIV): an Approach to Immunologic Classification of HIV
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Immunotyping of Human Immunodeficiency Virus Type 1 (HIV): an Approach to Immunologic Classification of HIV
... Because immunologic classification of human immunodeficiency virus type 1 (HIV) might be more relevant than genotypic classification for designing polyvalent ... See full document
10
Zidovudine and Perinatal Human Immunodeficiency Virus Type 1 Transmission: A Population-Based Approach
... the HIV/AIDS surveil- lance registry as HIV or AIDS ...an HIV-1– infected infant, which could result in an underesti- mation of the HIV-1 perinatal transmission ...possibility, ... See full document
9
Evolutionarily Conserved Epitopes on Human Immunodeficiency Virus Type 1 (HIV-1) and Feline Immunodeficiency Virus Reverse Transcriptases Detected by HIV-1-Infected Subjects
... among HIV-1 subtypes and do not mutate without negatively affecting viral fitness (19–21), would be valuable for an effective HIV-1 ...One approach is to select conserved, nonmutable ... See full document
12
Broad Neutralization of Human Immunodeficiency Virus Type 1 (HIV-1) Elicited from Human Rhinoviruses That Display the HIV-1 gp41 ELDKWA Epitope
... cold-causing human rhinovirus ...minimal immunologic similarity to HIV (data not ...displaying HIV-1 gp120 V3 loop sequences are able to elicit neutralizing responses against ... See full document
14
Simian Immunodeficiency Virus Engrafted with Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Epitopes: Replication, Neutralization, and Survey of HIV-1-Positive Plasma
... to approach the problem indirectly: for example, by first de- pleting a sample with monomeric gp120 and asking whether neutralizing activity remains in the depleted sample or by using a specific protein or peptide ... See full document
12
Comparison of Two Measures of Human Immunodeficiency Virus (HIV) Type 1 Load in HIV Risk Groups
... The processing and analysis of all samples of the same type took place in the same immunologic or virologic laboratory at The Johns Hopkins School of Public Health. The virology laboratories were certified ... See full document
6
Organization of Immature Human Immunodeficiency Virus Type 1
... on HIV and other retroviruses was based on the assumption of icosahedral symmetry for the interpretation of images (17–19, 23, 26, 31, 32, ...this approach is more difficult (47) and may be * Corresponding ... See full document
13
Immunologic function in a cohort of human immunodeficiency virus type 1 seropositive and negative healthy homosexual men
... The study objectives were to determine the early effects of human immunodeficiency virus type 1 HIV-1 infection on both phenotypic and functional immunologic markers in healthy homosexua[r] ... See full document
9
Potent inhibition of human immunodeficiency virus type 1 (HIV-1) replication by inducible expression of HIV-1 PR multimers.
... therapy approach to HIV-1 ...mutated HIV-1 which is resistant to the effects of this gene is highly ...an HIV-1 strain to develop resistance, the amino acid sequence of ... See full document
7
Mapping of Epitopes Exposed on Intact Human Immunodeficiency Virus Type 1 (HIV-1) Virions: a New Strategy for Studying the Immunologic Relatedness of HIV-1
... The five anti-V3 MAbs tested have previously been mapped with V3 peptides derived from MNp, IIIB, and RF (22, 23). However, interaction with these linear core epitopes accounts for only about 10% of the binding energy of ... See full document
8
Cross-Clade Inhibition of Recombinant Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus SIVcpz Reverse Transcriptases by RNA Pseudoknot Aptamers
... Comparative enzymatic activity. Purified RTs were diluted to equal active-site concentrations (0.4 nM), and their DDDP, RDDP, and RNase H activities were assessed in the absence of inhibitor, using a 75-fold excess of ... See full document
10
Cytopathicity of Human Immunodeficiency Virus Type 2 (HIV-2) in Human Lymphoid Tissue Is Coreceptor Dependent and Comparable to That of HIV-1
... that human immunodeficiency virus type 2 (HIV-2) is markedly less pathogenic than HIV-1 in ...with HIV-2 exhibit a remarkably slow rate of disease development, and ... See full document
7
Identification of a Subset of Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus Strains Able To Exploit an Alternative Coreceptor on Untransformed Human Brain and Lymphoid Cells
... rophages, as expected, but, surprisingly, also in the adult as- trocytes 004.2 (Fig. 7B). BMVECs and the adult astrocyte culture 001A were very weakly positive for CD4, explaining the inhibition observed with anti-CD4 ... See full document
15
Human Immunodeficiency Virus Type 1 (HIV-1) Quasispecies at the Sites of Mycobacterium tuberculosis Infection Contribute to Systemic HIV-1 Heterogeneity
... the human immunodeficiency virus type 1 (HIV-1) envelope gene (env) in HIV-1-infected patients with pulmonary tuberculosis (TB) compared to patients with ... See full document
10
A Helical Short-Peptide Fusion Inhibitor with Highly Potent Activity against Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus
... ABSTRACT Human immunodeficiency virus type 2 (HIV-2) has already spread to dif- ferent regions worldwide, and currently about 1 to 2 million people have been in- fected, calling for new ... See full document
15
Detection of human immunodeficiency virus type 1 (HIV 1) in urine cell pellets from HIV 1 seropositive individuals
... The slot blots contained PCR products from the following samples: Al to A6, peripheral blood mononuclear cells from HIV-1-seropositive patients; B1 to B6, fresh urine pellets from HIV-1-[r] ... See full document
5
Mechanisms of human immunodeficiency virus Type 1 (HIV-1) neutralization: irreversible inactivation of infectivity by anti-HIV-1 antibody.
... and virus isolate from dif- ferent sources) was generally better against laboratory-adapted isolates than against primary patient isolates (Table ...rising virus titers and declin- ing CD4 cell ... See full document
10
Functional and immunologic characterization of human immunodeficiency virus type 1 envelope glycoproteins containing deletions of the major variable regions.
... F105 antibody binding to the COS-1 cells expressing the AV1/2 and AV1/2/3 mutants was 2.4-fold and 13-fold, respectively, greater than that observed for cells expressing the wild-type gl[r] ... See full document
9
Defining the level of human immunodeficiency virus type 1 (HIV-1) protease activity required for HIV-1 particle maturation and infectivity.
... To overcome the requirement for autoprocessing, an at- tempt was made to express a synthetic gene which coded for the 99-amino-acid protease. No protease expression was ob- served when this gene was cloned into the ... See full document
8
Structural and Functional Characterization of Membrane Fusion Inhibitors with Extremely Potent Activity against Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus
... immunodeficiency virus (anti-HIV) activity and a low genetic barrier for drug ...divergent HIV-1 subtypes, its truncated versions, such as LP-55 (25-mer) and LP-65 (24-mer), still maintained ... See full document
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