[PDF] Top 20 Vpr and Vpu Are Important for Efficient Human Immunodeficiency Virus Type 1 Replication and CD4+ T-Cell Depletion in Human Lymphoid Tissue Ex Vivo
Has 10000 "Vpr and Vpu Are Important for Efficient Human Immunodeficiency Virus Type 1 Replication and CD4+ T-Cell Depletion in Human Lymphoid Tissue Ex Vivo" found on our website. Below are the top 20 most common "Vpr and Vpu Are Important for Efficient Human Immunodeficiency Virus Type 1 Replication and CD4+ T-Cell Depletion in Human Lymphoid Tissue Ex Vivo".
Vpr and Vpu Are Important for Efficient Human Immunodeficiency Virus Type 1 Replication and CD4+ T-Cell Depletion in Human Lymphoid Tissue Ex Vivo
... of CD4 ⫹ T cells in ex vivo human lymphoid tissue results mainly from the death of HIV-1-infected cells (27, ...and virus production may be different for ... See full document
5
Association of Nef with p21-Activated Kinase 2 Is Dispensable for Efficient Human Immunodeficiency Virus Type 1 Replication and Cytopathicity in Ex Vivo-Infected Human Lymphoid Tissue
... the human immunodeficiency virus type 1 (HIV-1) Nef protein with p21-activated kinase 2 (PAK2) has been proposed to play a role in T-cell activation, viral ... See full document
10
Presence of Host ICAM-1 in Laboratory and Clinical Strains of Human Immunodeficiency Virus Type 1 Increases Virus Infectivity and CD4+-T-Cell Depletion in Human Lymphoid Tissue, a Major Site of Replication In Vivo
... the ex vivo culture of human tonsillar tissue. This cell culture model has been used to study various aspects of HIV-1 pathogenesis (23, 24, 26, 29, ...the ex vivo ... See full document
11
Interactions between Human Immunodeficiency Virus Type 1 and Vaccinia Virus in Human Lymphoid Tissue Ex Vivo
... that ex vivo lymphoid tissues support productive infection by NYBCH, the VACV strain of ...both T and non-T lymphocytes, the latter more effi- ...and T cells among peripheral ... See full document
7
Human Immunodeficiency Virus Type 1 Variants Resistant to First- and Second-Version Fusion Inhibitors and Cytopathic in Ex Vivo Human Lymphoid Tissue
... in ex vivo HLT. In vivo, HIV-1 replicates in infected individuals mainly in the lymphoid tissues ...causes CD4 ⫹ -T-cell depletion in ex ... See full document
10
Viral Interactions in Human Lymphoid Tissue: Human Herpesvirus 7 Suppresses the Replication of CCR5-Tropic Human Immunodeficiency Virus Type 1 via CD4 Modulation
... and ex vivo-infected blocks of human lymphoid tissue 12 days ...to cell surface staining, counting beads (Caltag) were added to each tube to quantify cell ...total ... See full document
10
Proline 35 of Human Immunodeficiency Virus Type 1 (HIV-1) Vpr Regulates the Integrity of the N-Terminal Helix and the Incorporation of Vpr into Virus Particles and Supports the Replication of R5-Tropic HIV-1 in Human Lymphoid Tissue Ex Vivo
... cultured T cells, Vpr appears to play an important role in virus replication and pathogenesis in vivo (6, 12, ...23). Vpr is pack- aged into virus particles via an ... See full document
5
Differential Pathogenesis of Primary CCR5-Using Human Immunodeficiency Virus Type 1 Isolates in Ex Vivo Human Lymphoid Tissue
... of depletion of CCR5 ⫹ CD4 ⫹ T cells by a given viral isolate may have predictive value and reflects whether the individual from whom the virus was obtained eventually be- came a switch ... See full document
10
CpG Oligodeoxynucleotides Block Human Immunodeficiency Virus Type 1 Replication in Human Lymphoid Tissue Infected Ex Vivo
... HeLa- CD4 cells, suggesting that they work after viral ...HIV replication cycle, we quantified HIV DNA copies intracellularly in a one-round HIV replication assay in HLAC, in which the spreading HIV ... See full document
11
CD4 Down-Modulation by Human Immunodeficiency Virus Type 1 Nef Correlates with the Efficiency of Viral Replication and with CD4+ T-Cell Depletion in Human Lymphoid Tissue Ex Vivo
... caused efficient reduction of MHC-I cell surface expression but showed re- duced activity in down-regulation of CD4 ...in CD4 down- regulation, also exhibited two- to threefold higher levels ... See full document
5
Human Immunodeficiency Virus Type 1 Induces Apoptosis in CD4+ but Not in CD8+ T Cells in Ex Vivo-Infected Human Lymphoid Tissue
... Human lymphoid tissue ex vivo supports replication of dif- ferent HIV variants and does not require exogenous stimula- tion (20, ...that tissue blocks do not require ... See full document
8
Vpr Cytopathicity Independent of G2/M Cell Cycle Arrest in Human Immunodeficiency Virus Type 1-Infected CD4+ T Cells
... of Vpr mediates diverse Vpr ...helix. Vpr is a 14-kDa protein without known enzymatic activity or domain motifs, so it seems likely that it works by binding other, presumably cellular, ...cripple ... See full document
13
Korean Red Ginseng Slows Depletion of CD4 T Cells in Human Immunodeficiency Virus Type 1-Infected Patients
... mal human volunteers revealed that ginseng significantly in- creases neutrophil, CD4 T cell, and NK cell functions ...Th1 cell and macrophage cytokines (19), and this ... See full document
5
Determinant in Human Immunodeficiency Virus Type 1 for Efficient Replication under Cytokine-Induced CD4+ T-Helper 1 (Th1)- and Th2-Type Conditions
... cloned T-tropic HIV-1 (NL4-3) ...in efficient replication in the IL-12-induced Th1-type culture, we con- structed HIV-1 chimera clones from two parental isolates, JR-CSF and ... See full document
9
Simian-Human Immunodeficiency Virus Containing a Human Immunodeficiency Virus Type 1 Subtype-E Envelope Gene: Persistent Infection, CD4+ T-Cell Depletion, and Mucosal Membrane Transmission in Macaques
... of human immunodefi- ciency virus type 1 ...usage, cell tropism, and cyto- pathicity) and is the major target for antiviral immune re- sponses ... See full document
10
Nucleocytoplasmic Shuttling by Human Immunodeficiency Virus Type 1 Vpr
... HIV-1 Vpr and (ii) if one or both of these motifs are indeed involved in export, there is precedence for an overlapping import signal (41, ...GFP-PK– Vpr(1–71) fusion ...of ... See full document
11
Human immunodeficiency virus type 1 Vpu protein regulates the formation of intracellular gp160-CD4 complexes.
... Previous analyses of HIV-1 envelope synthesis in HeLa cells 30 indicated that intracellular transport of gp160 is very similar to that observed in virus-infected CD4+ T lymphocytes; howe[r] ... See full document
9
The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release.
... Because of its structural similarity to the membrane protein M2 encoded by influenza virus and the previously reported 4- to 10-fold reduction in progeny virion production associated wit[r] ... See full document
9
Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export.
... The amounts of the envelope glycoproteins gp160 and gp120 present in HeLa-T4 cell lysates transfected with HXBH10-vpu+/env+ and HXBH10-vpu-/env+ DNAs are similar in lysates of cells labe[r] ... See full document
8
Human immunodeficiency virus type 1 Vpu has a CD4- and an envelope glycoprotein-independent function.
... Because Vpu function was apparently not dependent on HIV-1 Env-gp expression, we wanted to determine whether the reduction in infectious virus produced by the vpu mutant could be due to [r] ... See full document
5
Related subjects