[PDF] Top 20 An Inducible Human Immunodeficiency Virus Type 1 (HIV-1) Vector Which Effectively Suppresses HIV-1 Replication
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An Inducible Human Immunodeficiency Virus Type 1 (HIV-1) Vector Which Effectively Suppresses HIV-1 Replication
... the HIV-1 genome for various gene therapy applications (2, 6, 10, 19, 20, 25–27, 29, 30, 34, 35, ...nondividing human cells such as macrophages, a tar- get for HIV-1 ...known ... See full document
7
Transduction of Cellular Sequence by a Human Immunodeficiency Virus Type 1-Derived Vector
... an HIV-1 vector provi- ...study HIV-1 mutational ...viral vector in conjunction with a packaging cell ...retroviral replication to a single cycle and identify mutations in ... See full document
5
Susceptibility of Rat-Derived Cells to Replication by Human Immunodeficiency Virus Type 1
... early HIV-1 gene expression, but only macrophages and microglia support sig- nificant expression of late, fully processed HIV-1 gene prod- ...the HIV-1 replication cycle ... See full document
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Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A.
... facilitate HIV-1 uncoating in target cells (5, 8, 12, 24, ...targeting HIV-1 to an alternate entry pathway influences the requirement for CyPA incorporation, we produced ... See full document
7
In Vitro Suppression of Human Immunodeficiency Virus Type 1 Replication by Measles Virus
... measles, human immunodeficiency virus type 1 (HIV-1)-infected children have a transient, but dramatic, decrease in plasma HIV-1 RNA levels ...by which ... See full document
9
Induction of CD4 expression and human immunodeficiency virus type 1 replication by mutants of the interferon-inducible protein kinase PKR.
... of HIV-1 5 9 LTR and nuclear extracts from untreated or PMA-treated ...6), which were competed by an excess of cold dsDNA oligonucleotide (lane ... See full document
8
Inducible human immunodeficiency virus type 1 packaging cell lines.
... containing HIV gag, pol, tat, and vif gene open reading frames, and it has mutations, deletions, or disruptions of the packaging signal ( C ), vpr, vpu, rev, env, nef, and the 3 9 long terminal repeat ... See full document
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Intracellular expression of human immunodeficiency virus type 1 (HIV-1) protease variants inhibits replication of wild-type and protease inhibitor-resistant HIV-1 strains in human T-cell lines.
... budding HIV-1 virion, and evaluation of antiretroviral activity in these cells are im- portant next steps which must be taken towards the develop- ment of a clinically relevant gene therapy ...with ... See full document
8
Inhibition of Human Immunodeficiency Virus Type 1 (HIV-1) Replication by a Two-Amino-Acid Insertion in HIV-1 Vif from a Nonprogressing Mother and Child
... on HIV-1 replication, the nature of the Vif defect from the strain from patient X was further investigated by examining polypeptide ...expression vector (Stratagene, La Jolla, Cal- ...(A) ... See full document
7
Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector.
... To determine whether transfer of HIV-1 vectors to Jurkat cells could occur without the transfer of replication-competent virus, two separate plasmids encoding the HIV-1 proteins were uti[r] ... See full document
5
Potent inhibition of human immunodeficiency virus type 1 (HIV-1) replication by inducible expression of HIV-1 PR multimers.
... to HIV-1 infection. This gene contains many attributes which make it ideal as an antiviral ...mutated HIV-1 which is resistant to the effects of this gene is highly ...an ... See full document
7
Inhibition of Human Immunodeficiency Virus Type 1 (HIV-1) Replication by HIV-1-Based Lentivirus Vectors Expressing Transdominant Rev
... the vector RNA should have a competitive advantage over the wild-type viral genomic RNA for transport and ...6, vector HSN2 inhibits HIV-1 replication better than vector ... See full document
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Simian Immunodeficiency Virus Engrafted with Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Epitopes: Replication, Neutralization, and Survey of HIV-1-Positive Plasma
... not effectively neutral- ized by any of the monoclonal antibodies tested ...of HIV-positive plasma with HIV epitope-en- grafted ...of HIV-positive plasmas for 2F5-like and 4E10-like ... See full document
12
Human Herpesvirus 6 Infects Dendritic Cells and Suppresses Human Immunodeficiency Virus Type 1 Replication in Coinfected Cultures
... by which HHV-6 suppresses HIV replica- tion in coinfected DC cultures is not ...suppress HIV replication ...or HIV coreceptors do not appear to be involved (Table ...blocking ... See full document
10
Minimal Requirement for a Lentivirus Vector Based on Human Immunodeficiency Virus Type 1
... the vector particles with vesicular stomatitis virus glycoprotein ...of HIV vectors for use in gene ...retroviral vector, viral components (gag-pol, env, and the vector genome) must be ... See full document
6
Sequence of Human Immunodeficiency Virus Type 1 (HIV-1) Gag Localization and Oligomerization Monitored with Live Confocal Imaging of a Replication-Competent, Fluorescently Tagged HIV-1
... infectious human immunodeficiency virus (HIV) requires that Gag transport and oligomer- ization be coordinated with its association with other viral proteins, viral RNAs, and cellular ...a ... See full document
12
Generation and characterization of a human immunodeficiency virus type 1 (HIV-1) mutant resistant to an HIV-1 protease inhibitor.
... Viruses obtained from treated and untreated cultures were called the escape and passaged viruses, respectively, and were used to infect MOLT-4 cells to establish chronically infected pro[r] ... See full document
7
Human Immunodeficiency Virus Type 1 (HIV-1) Vpr Enhances Expression from Unintegrated HIV-1 DNA
... on HIV-1 replication utilized integration- competent virus, and the increase in viral replication was also only a few ...as HIV-1 DNA integrated into the chromo- some. ... See full document
11
Human Immunodeficiency Virus Type 1 Infection and Replication in Normal Human Oral Keratinocytes
... with HIV-1. Sixteen hours after exposure to cell-free HIV-1, NHOKs were assayed for proviral DNA sequences by PCR amplification of R/U5 (M667 and AA55) and LTR/gag ...with which it ... See full document
7
Comparative analyses of human immunodeficiency virus type 1 (HIV-1) and HIV-2 Vif mutants.
... by human immunodeficiency virus (HIV) and other primate immunodeficiency viruses, have com- plex genomes that encode a number of regulatory and acces- sory gene products ...for ... See full document
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