[PDF] Top 20 Induction of Potent Human Immunodeficiency Virus Type 1-Specific T-Cell-Restricted Immunity by Genetically Modified Dendritic Cells
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Induction of Potent Human Immunodeficiency Virus Type 1-Specific T-Cell-Restricted Immunity by Genetically Modified Dendritic Cells
... naı¨ve T cells and the development of HIV-specific CTL in the animals because we had seen potent T-cell responses induced by GMDC in vitro and a high rate of DNA expression in ... See full document
8
Induction of Human Immunodeficiency Virus Type 1-Specific T Cells by a Bluetongue Virus Tubule-Vectored Vaccine Prime-Recombinant Modified Virus Ankara Boost Regimen
... reliable induction of antibodies broadly neutralizing human immunodefi- ciency virus type 1 (HIV-1), vaccine efforts have shifted toward the induction of ... See full document
12
Induction of Potent CD8+ T-Cell Responses by Novel Biodegradable Nanoparticles Carrying Human Immunodeficiency Virus Type 1 gp120
... from human immunodeficiency virus type 1 (HIV-1) infection in developed ...induce virus-specific neutralizing antibodies and cyto- toxic T-lymphocyte (CTL) ... See full document
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Dendritic Cell–T-Cell Interactions Support Coreceptor-Independent Human Immunodeficiency Virus Type 1 Transmission in the Human Genital Tract
... and T cells, rather than DC, may be the early targets for R5-tropic HIV-1 entry following sexual ...mucosal T cells ...cosal T cells and CXCR4 is abundantly expressed on ... See full document
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Neutralizing Monoclonal Antibodies Block Human Immunodeficiency Virus Type 1 Infection of Dendritic Cells and Transmission to T Cells
... envelope-specific human IgG MAbs were studied because they were previously shown to neutralize HIV-1 in- fection of activated T ...unstimulated T cells. Neu- tralization ... See full document
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Induction of Anti-Human Immunodeficiency Virus Type 1 (HIV-1) CD8+ and CD4+ T-Cell Reactivity by Dendritic Cells Loaded with HIV-1 X4-Infected Apoptotic Cells
... anti-HIV-1 T-cell re- sponses in peripheral blood mononuclear cells (PBMC) of persons with chronic HIV-1 infection by autologous DC loaded in vitro with various forms of HIV-1 X4 ... See full document
8
Human Immunodeficiency Virus Type 1 Vpr Impairs Dendritic Cell Maturation and T-Cell Activation: Implications for Viral Immune Escape
... the virus particles but also support HIV-1 infection and express HIV-1 viral proteins through the long terminal repeat pro- moter ...for virus binding and infection, HIV-1 virions also ... See full document
14
Potent and Specific Inhibition of Human Immunodeficiency Virus Type 1 Replication by RNA Interference
... the cell nucleus but is exported and expressed in the presence of the HIV-1 Rev nuclear RNA export ...this induction is blocked by the Rev-specific siRNA but not by either the sense or ... See full document
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Induction of T-Cell Immunity to Antiretroviral Drug-Resistant Human Immunodeficiency Virus Type 1
... I type A*0101/0205, B*0702/0801, Cw*0701/0702), a CD8 T-cell response was repeatedly de- tected against the pool containing resistant protease ...CD8 T-cell responses against both the ... See full document
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Infection of Specific Dendritic Cells by CCR5-Tropic Human Immunodeficiency Virus Type 1 Promotes Cell-Mediated Transmission of Virus Resistant to Broadly Neutralizing Antibodies
... a potent mechanism to in- hibit HIV infection in vivo and would be a desirable feature of an immune response elicited by a highly effective AIDS vac- cine, but HIV has evolved a number of mechanisms to evade ... See full document
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Multiple T-Cell Responses to Human Immunodeficiency Virus Type 1 Are Enhanced by Dendritic Cells
... ⫹ T-cell reactivity to single HIV-1 peptides repre- senting the minimal, optimal HLA A*0201 epitope SL9, as well as to 15-mer and 20-mer extensions of this ...⫹ T-cell responses were ... See full document
14
Primary Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses Induced by Myeloid Dendritic Cells
... ⫹ T-cell responses to the various proteins of human immunodeficiency virus type 1 (HIV-1) are considered important in host control of infection and prevention of ... See full document
12
Human immunodeficiency virus type 1 strains of subtypes B and E replicate in cutaneous dendritic cell-T-cell mixtures without displaying subtype-specific tropism.
... of T cells permits active HIV-1 ...fluorescence-activated cell sorter analysis and/or immunohistochemical analysis) (data not shown), but a robust HIV-1 infection was observed within a ... See full document
7
Virus-Specific Cytotoxic T Lymphocytes in Human Immunodeficiency Virus Type 1-Infected Chimpanzees
... effector cells specific for target cells pulsed with three different peptides, all three peptides were used in this ...effector cells from chimpanzees C-424 and C-487 lysed autologous but not ... See full document
5
Role of Human Immunodeficiency Virus (HIV)-Specific T-Cell Immunity in Control of Dual HIV-1 and HIV-2 Infection
... Washington Human Subjects Institutional Review ...⫹ T-cell counts of ⱖ350 cells/l at their screening visit, were invited to enroll in an immunological ...⫹ T-cell counts, PCR ... See full document
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Human immunodeficiency virus type 1 Nef does not alter T-cell sensitivity to antigen-specific stimulation.
... 103.13 cells are shown in ...to cell cycle progression in T cells (39, ...infected T cells could be selected for by G418 ...Fig. 1 to compare levels of HIV production that ... See full document
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Adenovirus-pulsed dendritic cells stimulate human virus-specific T-cell responses in vitro.
... adenovirus-infected cells in rodents, as shown by using transgenic mice lacking components of this pathway (42), and our results show that most of the killing of adenovirus-infected human cells is ... See full document
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Inhibition of Human Immunodeficiency Virus Type 1 Replication in Primary CD4+ T Lymphocytes, Monocytes, and Dendritic Cells by Cytotoxic T Lymphocytes
... these cell types was less efficient than in lymphocytes despite a 10-fold higher initial input of virus ...B14- restricted clone was completely inhibitory for detectable p24 antigen ...target ... See full document
5
DC-SIGN Mediates Cell-Free Infection and Transmission of Human T-Cell Lymphotropic Virus Type 1 by Dendritic Cells
... B-THP-1 cells leads to produc- tive ...B-THP-1/DC-SIGN cells, we proceeded to determine whether viral entry was followed by productive ...B-THP-1/DC-SIGN cells was analyzed ... See full document
14
The dual role of dendritic cells in the immune response to human immunodeficiency virus type 1 infection
... the specific roles of DCs during HIV-1 ...‘Langerhan’s cell paradigm’ of DC function by including LN-resident immature DCs and multiple mat- uration/activation ...observing human lymphoid ... See full document
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