[PDF] Top 20 Inefficient Human Immunodeficiency Virus Replication in Mobile Lymphocytes

... fast-replicating virus in vivo and in cell ...⫹ lymphocytes has profoundly deleterious effects on the ability of HIV to ...viral replication in shaken lym- phocytes was observed with a panel of ... See full document

... We have examined the cellular and virological mechanisms underlying these phenomena. We focused a large part of our study on the behavior of X4 strains, which were widely believed not being able to replicate in iDCs (14, ... See full document

... neutralize virus in autologous CD4 T ...inhibit replication of primary HIV isolates over 7 to 10 days in vitro, using an adaptation of a previously reported assay ...influence virus ... See full document

... Constitutive expression of HIV-1 C -gag antisense sequences in CEMSS cells. The anti-HIV-1 efficacy of C -gag complemen- tary transcripts (Fig. 1A) was evaluated in the CD4 1 human T-lymphoid CEMSS cell line. ... See full document

... Inhibition of HIV-1 replication in primary lymphocytes. The experiments described above with transformed T cells were not feasible with primary cells, since treatment of PBMCs with lentiviral vectors ... See full document

... of human immunodeficiency virus type 1 (HIV-1) in T lymphocytes involves a complex interac- tion between cellular and viral regulatory proteins and their target sequences within the long ... See full document

... The inefficient replication of SIVagm Vpr mutants in PBMCs is reminiscent of reports of the replication of SIVmac and HIV-2 Vpx mutants in this cell type (16, 36, ...in replication in PBMCs as ... See full document

... HIV-positive lymphocytes were localized in both submucosal and mucosal layers in the vicinity of epithelial cells bearing HIV-1 DNA sequences ...The virus was localized in the interepi- thelial space bound ... See full document

... the human immunodeficiency virus (HIV) ...all virus is not elim- inated from the body. Virus survival of HAART is thought to be due to (i) outgrowth of viral strains with lower ... See full document

... A soluble protein derived from an invasive strain of Entamoeba histolytica amoebic antigen [AA] was used to study the lymphoblastic responses of T lymphocytes derived from 8 HIV-seronega[r] ... See full document

... blood lymphocytes through a mechanism that requires cleavage of the F protein (31) and impaired protein kinase B (Akt kinase) activation (4), disrupting the downstream pathway critical to IL-2-dependent ... See full document

... To determine whether transfer of HIV-1 vectors to Jurkat cells could occur without the transfer of replication-competent virus, two separate plasmids encoding the HIV-1 proteins were uti[r] ... See full document

... viral replication were different in CD4 1 and CD8 1 ...HIV-1 replication, while CD8 1 cells were resistant, in accordance with previous observations (11, ... See full document

... necessary for production of infectious virions by nonpermissive cells (human lymphocytes and macrophages) but not by permissive cells such as HeLa-CD4. It had been proposed that permissive cells may contain ... See full document

... the replication of different HIV-1 strains in adult peripheral blood-derived monocytes and ...PHA-P-stimulated lymphocytes were incubated overnight with OTC or medium alone, inoculated with different HIV-1 ... See full document

... FIG. 3. ADAR1-p150 and TRBP2 reverse PKR inhibition of HIV expression and virus production. (A) ADAR1-p150 and TRBP2 reverse PKR inhibition of HIV LTR expression. HEK 293T cells were transfected with 0.05 ␮ g of ... See full document

... viral replication, which exceeded that of monocytes and DC alone ...infected lymphocytes alone ...HIV-1 replication by DC-lymphocyte clusters at the earliest time point, but inhibition was blunted or ... See full document

... 6596-6604 0022-538X/93/1 16596-09$02.00/0 Copyright © 1993, American Society for Microbiology Phosphatidylcholine Hydrolysis Activates NF-KB and Increases Human Immunodeficiency Virus Re[r] ... See full document

... Deletion mutants in the gene encoding the herpes simplex virus type I immediate-early protein ICPO exhibit impaired growth in cell culture.. The herpes simplex virus type 1 alpha protein[r] ... See full document

... HIV-1 replication in macrophages ...T-tropic virus, supplies different signals than CCR5 that in turn activate ...vated virus able to bind CCR4 did not induce iNOS (data not shown) or TNF-␣ ...HIV-1 ... See full document