[PDF] Top 20 Interference of interleukin-10 with human immunodeficiency virus type 1 replication in primary monocyte-derived macrophages.
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Interference of interleukin-10 with human immunodeficiency virus type 1 replication in primary monocyte-derived macrophages.
... IL-10 treatment of MDM 24 h after HIV-1 inoculation in combination with IL-3 pretreatment resulted in dose-dependent inhibition of virus production, but even at the highest concentration[r] ... See full document
9
Selectively Reduced tat mRNA Heralds the Decline in Productive Human Immunodeficiency Virus Type 1 Infection in Monocyte-Derived Macrophages
... rescues virus production from long-term- infected ...in virus expression at a concentration shown previously to induce HIV-1 production from the latently infected promono- cytic cell line U1 (17), a ... See full document
11
Interleukin-8 Stimulates Human Immunodeficiency Virus Type 1 Replication and Is a Potential New Target for Antiretroviral Therapy
... family, interleukin-8 (IL-8) and growth- regulated oncogene alpha (GRO-␣), may play in controlling HIV-1 replication and pathogenesis has not been well estab- ...stimulate monocyte adherence, ... See full document
8
Potent and Specific Inhibition of Human Immunodeficiency Virus Type 1 Replication by RNA Interference
... in human AB serum until ...with 10% human AB serum (Sigma) and 10 U of interleukin-2 (R&D Systems) per ml as described previously ...stocks. Human 293T cells were maintained ... See full document
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55- and 75-kilodalton tumor necrosis factor receptors mediate distinct actions in regard to human immunodeficiency virus type 1 replication in primary human macrophages.
... for human TNF-R1 and TNF-R2, ...in human KYM-1 cells indis- tinguishable from that of wild-type TNF-a ...has 10 times lower binding affinity for TNF-R2 compared with wild-type ... See full document
7
Susceptibility of Rat-Derived Cells to Replication by Human Immunodeficiency Virus Type 1
... of primary rat microglia for the HIV-1 replication cycle was also studied using pseudotyped viruses as described ...with primary macrophages, rat microglia supported robust early ... See full document
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Macrophages in Vaginal but Not Intestinal Mucosa Are Monocyte-Like and Permissive to Human Immunodeficiency Virus Type 1 Infection
... Vaginal macrophages display a monocyte-like ...gut macrophages, we analyzed blood monocytes and mucosal macrophages from normal vagina and jejunum by flow ...(Fig. 1). Blood mono- cytes ... See full document
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vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages, producing attenuated progeny virus.
... wt virus, based on results from nine independent infections, was 10% (Table ...mutant virus infec- tion in MDM was persistent, lasting for at least 30 days of observation ...cell- derived ... See full document
10
Proteomic and Biochemical Analysis of Purified Human Immunodeficiency Virus Type 1 Produced from Infected Monocyte-Derived Macrophages
... from monocyte-derived macrophages presented here reveals many new proteins not previously described in HIV-1 ...(Table 1) (49, ...8, 10, 12, and 15) is consistent with the ... See full document
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Cytokine Regulation of Human Immunodeficiency Virus Type 1 Entry and Replication in Human Monocytes/Macrophages through Modulation of CCR5 Expression
... Human macrophages express chemokine receptors that act as coreceptors for human immunodeficiency virus type 1 (HIV-1) and are major targets for HIV-1 ... See full document
6
Differential Tropism and Chemokine Receptor Expression of Human Immunodeficiency Virus Type 1 in Neonatal Monocytes, Monocyte-Derived Macrophages, and Placental Macrophages
... monocytes, monocyte-derived macrophages (MDMs), and placental macrophages ...strain replication preceded reverse transcription. Neonatal monocyte susceptibility to PR ... See full document
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Human Immunodeficiency Virus Type 1: Resistance to Nucleoside Analogues and Replicative Capacity in Primary Human Macrophages
... WT virus in MDMs, whereas no significant differences were seen in P4 cells or in mitogen-stimulated ...HIV replication or reduced RT processivity, mostly in the context of the M184V mutation (9, 10, ... See full document
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Susceptibility of Mink (Mustera vision)-Derived Cells to Replication by Human Immunodeficiency Virus Type 1
... of human CycT1 with Tat is conserved in mink CycT1 and is likely to explain the functional integrity in mediating Tat trans- activation ...and human cells ...while primary rat macrophages and ... See full document
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Role of CXCR4 in Cell-Cell Fusion and Infection of Monocyte-Derived Macrophages by Primary Human Immunodeficiency Virus Type 1 (HIV-1) Strains: Two Distinct Mechanisms of HIV-1 Dual Tropism
... X4 primary isolates evaluated here, the T-tropic X4 prototype fused poorly with primary macro- phages, which indicates that inefficient entry is a major element in its restriction in macrophages, ... See full document
9
CXCR4 as a Functional Coreceptor for Human Immunodeficiency Virus Type 1 Infection of Primary Macrophages
... of macrophages derived from homozygous D 32/ D 32 CCR5 ...by primary SI viruses. Macrophages were isolated from blood monocytes by plastic adherence as previously described ...in 10% ... See full document
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Herpes simplex virus type 2 infection increases human immunodeficiency virus type 1 entry into human primary macrophages
... the human monocyte U937 cell line (ATCC ® Number ...the virus was grown and titrated by plaque assay on African green monkey kidney cells (Vero), as previously described ...× 10 6 ) were ... See full document
6
Human Immunodeficiency Virus Type 1 Entry into Macrophages Mediated by Macropinocytosis
... and replication of HIV(VSV) pseudotypes, which require a low pH to fuse in endosomes, was inhibited by bafilomycin ...in primary macrophages and DMA and bafilomycin A1 resis- tant in an ... See full document
12
Phosphatidylinositol 3-Kinase Regulates Human Immunodeficiency Virus Type 1 Replication following Viral Entry in Primary CD4+ T Lymphocytes and Macrophages
... for macrophages. Cells were treated for 1 h at 37°C with 5 to 20 M LY294002 (Sigma), 100 nM wortmannin (Sigma), 50 M benzyloxy- carbonyl-Val-Ala-Asp-fluoromethyl ketone (z-VAD-FMK) (Calbiochem) or di- ... See full document
11
Importin 7 May Be Dispensable for Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus Infection of Primary Macrophages
... in monocyte-derived macro- phages seeded into 24-well plates with 180 pmol siRNA trans- fected once a day for 2 days ...in macrophages. Macrophages were transfected with NS control or IPO7 ... See full document
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Nitric Oxide Synthesis Enhances Human Immunodeficiency Virus Replication in Primary Human Macrophages
... in human immunodeficiency virus (HIV) infection patho- genesis, not only by their contribution to virus dissemination and persistence in the host but also through the dysregulation of immune ... See full document
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