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[PDF] Top 20 Leukemia cells induce changes in human bone marrow stromal cells

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Leukemia cells induce changes in human bone marrow stromal cells

Leukemia cells induce changes in human bone marrow stromal cells

... stem cells pluripotency, TGF-β signaling and carcinoma signaling (Table ...of leukemia cells on BMSCs co-cultured in direct ...different leukemia cell lines in direct contact. The cells ... See full document

14

Aging of human bone marrow – functional and

epigenetic changes in senescent mesenchymal

stromal cells

Aging of human bone marrow – functional and epigenetic changes in senescent mesenchymal stromal cells

... sample, cells were harvested 24 h after the last ...the cells were crucial for the signal-to-noise ratio of the ATAC-seq ...adherent cells were counted by a DAPI nucleus staining followed by an ... See full document

136

Endothelial cells influence the osteogenic potential of bone marrow stromal cells

Endothelial cells influence the osteogenic potential of bone marrow stromal cells

... the changes in ALP expression described above, the key transcription fac- tor Runx2 was tested by ...synergistically induce osteoblastic differ- entiation ... See full document

9

Interferon γ induced compositional changes in human bone marrow derived mesenchymal stem/stromal cells

Interferon γ induced compositional changes in human bone marrow derived mesenchymal stem/stromal cells

... protein changes in bone marrow derived MSC as this could provide new insights regarding the immunoregu- latory capacities of these ...compositional changes might also offer details of the dif- ... See full document

14

Juxtacrine Interaction of Macrophages and Bone Marrow Stromal Cells

Juxtacrine Interaction of Macrophages and Bone Marrow Stromal Cells

... significant changes, instead of the conditioned media from the co-culture of apoptotic BMSCs and ...primary cells to produce IL-6 triggered by the juxtacrine ...of human myeloma-derived cell lines ... See full document

40

In vitro expansion affects the response of human bone marrow stromal cells to irradiation

In vitro expansion affects the response of human bone marrow stromal cells to irradiation

... Background: Bone marrow stromal cells (BMSCs) are extensively used in regeneration therapy and cytology experiments simulate how BMSCs respond to ...BMSCs changes during in vitro ... See full document

15

Pro-fibrotic phenotype of bone marrow stromal cells in Modic type 1 changes

Pro-fibrotic phenotype of bone marrow stromal cells in Modic type 1 changes

... anti- human FAK (#3285), 1 : 1,000 rabbit anti-human p-FAK (Tyr397) (#3283), 1 : 1,000 rabbit anti-human integrin β1 (#4706); or from Lucerna: 1 : 2,000 rabbit anti-human α-SMA ... See full document

22

Targeting the autophagy in bone marrow stromal cells overcomes resistance to vorinostat in chronic lymphocytic leukemia

Targeting the autophagy in bone marrow stromal cells overcomes resistance to vorinostat in chronic lymphocytic leukemia

... cancer cells with defects in apoptosis, autophagy promotes cell survival, whereas other studies suggest that autophagy provides a protective function to inhibit ...cancer cells promote autophagy and aerobic ... See full document

20

Marrow stromal stem cells

Marrow stromal stem cells

... models, human BMT following a myeloablative regimen was recently attempted in chil- dren with severe osteogenesis imperfecta ...1–2% bone cells (assessed by ex vivo culture of recipient ... See full document

7

The Yin and Yang of the Bone Marrow Microenvironment: Pros and Cons of Mesenchymal Stromal Cells in Acute Myeloid Leukemia

The Yin and Yang of the Bone Marrow Microenvironment: Pros and Cons of Mesenchymal Stromal Cells in Acute Myeloid Leukemia

... This is partially imputable to the poor characterization of the immunosuppressive and anti-inflammatory properties of MSCs derived from AML patients. As discussed before, MSCs contribute to the immune responses. Many ... See full document

15

Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton’s jelly mesenchymal stromal cells

Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton’s jelly mesenchymal stromal cells

... to induce irreversible liver fibrosis. Ex-vivo expanded, pooled human MSCs obtained from BM and WJ were intravenously administered into rats with liver fibrosis at a dose of 10 × 10 6 ... See full document

12

Age-related Changes in Bone Marrow Mesenchymal Stromal Cells: A Potential Impact on Osteoporosis and Osteoarthritis Development

Age-related Changes in Bone Marrow Mesenchymal Stromal Cells: A Potential Impact on Osteoporosis and Osteoarthritis Development

... mesenchymal stromal cells (MSCs) in the bone marrow (BM) niche has been suggested as one of the factors contributing to bone abnormalities in OP and ...senescent cells, and ... See full document

10

Eph/Ephrin-mediated stimulation of human bone marrow mesenchymal stromal cells correlates with changes in cell adherence and increased cell death

Eph/Ephrin-mediated stimulation of human bone marrow mesenchymal stromal cells correlates with changes in cell adherence and increased cell death

... We also wanted to verify the effects of either blockade or activation of Eph/Ephrin signaling on in-vitro expan- sion, survival, and proliferation of MSC. As known already, it is difficult to expand ex vivo fresh BM-MSC, ... See full document

16

Comparison of endometrial regenerative cells and bone marrow stromal cells

Comparison of endometrial regenerative cells and bone marrow stromal cells

... Gene expression analysis revealed considerable simi- larities between ERC and BMSC, but there were also distinct differences between these two types of cells. Many immunity and inflammation related pathways were ... See full document

14

Isolation, characterization and analysis of human stromal cells obtained from bone marrow

Isolation, characterization and analysis of human stromal cells obtained from bone marrow

... En el caso de la Safranina-O/Fast Green (Fig. 6) también se resalta el contenido de GAG, pero la presencia de éstos es menor. Esto puede ser debido a que la tinción de Fast Green se su[r] ... See full document

42

Original Article Bone marrow stromal stem cells induce autophagy that may exert neuroprotective effects

Original Article Bone marrow stromal stem cells induce autophagy that may exert neuroprotective effects

... therapy. Bone marrow stromal cells (BMSCs) have many advantages compared to fetal cells or embryonic stem ...stem cells derived from other sources because of their low ... See full document

9

Effect of interleukin 1β treatment on co cultures of human meniscus cells and bone marrow mesenchymal stromal cells

Effect of interleukin 1β treatment on co cultures of human meniscus cells and bone marrow mesenchymal stromal cells

... meniscus cells (MCs) and BMSCs Firstly, we established that chondrogenic co-culture of MCs and BMSCs resulted in a synergistically enhanced cartilaginous matrix formation relative to mono-cultures of MCs and BMSCs ... See full document

11

Pre-clinical studies of bone regeneration with human bone marrow stromal cells and biphasic calcium phosphate

Pre-clinical studies of bone regeneration with human bone marrow stromal cells and biphasic calcium phosphate

... for bone formation before scaling up to relevant clinical numbers of ...large bone defects of 5 to 10 cm 3 shall be ...ectopic bone and hematopoietic compartment formation, as well as bone ... See full document

15

Induction of Bone Marrow Stromal Cells into Cholinergic-Like Cells by Nerve Growth Factor

Induction of Bone Marrow Stromal Cells into Cholinergic-Like Cells by Nerve Growth Factor

... harvested cells were seeded in a 75-cm 2 flask (Nunc, Denmark) and a 5% CO 2 incubator at ...floating cells including hematopoietic cells and debris were removed by changing the ...adherent ... See full document

7

Osteogenic differentiation of bone marrow stromal cells is hindered by the presence of intervertebral disc cells

Osteogenic differentiation of bone marrow stromal cells is hindered by the presence of intervertebral disc cells

... IVD cells on MSC osteogenesis, we analyzed the endogenous expression of major BMP antagonists ( CHRD , NOG , and GREM1 ) in IVD ...both human NPCs and AFCs, and were abundant in ...IVD cells can ... See full document

10

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