[PDF] Top 20 Long noncoding RNAs in renal diseases

... VHL-mutant RCC cell yet promoting the growth of VHL-normal RCC cell [57]. Decreases of lncRNAs such as NBAT-1 (neuroblastoma associated transcript-1) [58] and CASC2 [59] (cancer suscepti- bility candidate 2) are ... See full document

... of noncoding RNAs, particularly microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), in the pathogenesis and regulation of the ocular ...eye diseases, as well as the roles of ... See full document

... We defined four different signatures of LncRNAs and pseudogenes, which separately predict MS and MDF. Although these signatures of LncRNAs and pseudo- genes in RCC have not been validated, their associations with cancer ... See full document

... “noncoding RNAs” (ncRNAs) are a group of RNAs that do not code for proteins, and they are categorized as structural RNAs and regulatory ...and long ncRNAs function as regulatory ... See full document

... The vast span of non-coding regions brings us to question of its role in the cellular system, especially the poorly understood lncRNAs. The idea of lncRNAs first surfaced some two decades ago with the description of ... See full document

... Some nuclear DNA-encoded lncRNA could play a role in mitochondria-mediated apoptosis. ENS- MUST00000136025 is a nearby enhancer-like lncRNA of its neighboring BIM gene; BIM is a pro-apoptotic pro- tein and potentiates ... See full document

... infectious diseases or cellular stressors, and it is possible that a phenotype in mice lacking Neat1 may only be apparent following an environmental manipulation, such as viral infection or exposure to microbes, ... See full document

... Abstract: Long noncoding RNAs (lncRNAs) are typically defined as transcripts longer than 200 ...neurological diseases such as epilepsy, neurodegenerative conditions, and genetic ... See full document

... Long noncoding RNA (lncRNA) is a leader of the degree of more than 200 nucleotides, almost do not have the function of protein coding endogenous RNA ...human diseases, especially in oncology, more ... See full document

... Growing evidence shows that the vast majority of disease- associated genetic variations occur in the noncoding por- tion of the genome. In fact, whereas only 7% of disease- associated SNPs localize in ... See full document

... of long noncoding RNAs (lncRNAs) are very common in clear cell renal cell carci- noma (ccRCC), and some of these have been reported to be highly correlated with prognosis of ccRCC ... See full document

... adjacent noncoding transcript 1 (Pantr1; LINC01158 in human) lncRNA, which is transcribed divergently from the Pou3f3 (Brn1) gene ...specific long sequences in their loci for ... See full document

... (miRNAs), long ncRNAs (LncRNAs) and the newly defined circular RNAs (circRNAs) in terms of length and ...Indeed, RNAs play fundamental roles in ...of RNAs, are critical [13, ...~21-nucleotide- ... See full document

... In our previous study, the oncogenic lncRNA land- scape was identified and validated in breast cancer [10]. Moreover, we also identified an lncRNA, linc00152, which functions as a tumor propellant in breast cancer and ... See full document

... Long noncoding RNAs, RNA transcripts 200 nucleotides or longer that do not encode a functional protein, have been shown to regulate a wide variety of biological processes (Wapinski and Chang 2011; Li ... See full document

... Noncoding RNAs (ncRNAs) are a superclass of endogenous, non-protein-coding RNA transcripts, many of which have essential functions in various cellular ...are long ncRNAs ... See full document

... Microarray of lncRNAs was performed by Beijing CapitalBio Technology Co., Ltd (Beijing, People’s Republic of China). lncRNAs from all canonical databases, NCBI Refseq, UCSC Known Gene, NRED, and RNAdb, were covered with ... See full document

... Long noncoding RNA (lncRNA) is operationally defined as RNA longer than 200 bases that does not encode mRNA, rRNA or tRNA [1,2]. Although several lncRNAs have been sporadically identified and characterized ... See full document

... Abstract: Over the last two decades, genome-wide studies have revealed that only a small fraction of the human genome encodes proteins; long noncoding RNAs (lncRNAs) account for 98% of the total ... See full document

... Discovery of L. monocytogenes sRNA rli32 as a potent IFN- ␤ inducer. We sought to define the composition of the secreted RNA fraction that was shown to be a strong inducer of IFN- ␤ response (16). The secRNome of L. ... See full document