[PDF] Top 20 Lung function discordance in monozygotic twins and associated differences in blood DNA methylation
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Lung function discordance in monozygotic twins and associated differences in blood DNA methylation
... identified DNA methylation at several CpG sites associated with intra-pair difference in level of lung function for the different ...significant associated finding for the level ... See full document
13
Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation
... DNA methylation is the most widely studied epigenetic process and is one of the mechanisms that are involved in tissue differentiation during early ...in DNA methylation state between the ... See full document
15
A Genome-Wide Scan of DNA Methylation Markers for Distinguishing Monozygotic Twins
... of monozygotic (MZ) twins remains unresolved using common forensic DNA typing ...MZ twins as suspects, the twins had to be released due to inability to identify which of the pair was ... See full document
10
11p15 DNA-methylation analysis in monozygotic twins with discordant intrauterine development due to severe twin-to-twin transfusion syndrome
... growth discordance and IGF-II serum ...been associated with size at birth ...growth-discordant monozygotic twin pairs so ...cord blood samples of TTTS donors as compared to both recipients and ... See full document
10
Within-pair differences of DNA methylation levels between monozygotic twins are different between male and female pairs
... are associated with atrial fibrillation [41] and gastric dilatation [42], respectively, both of which are also male dominant [43, ...in blood glucose homeostasis [45] and IRS4 encodes the insulin receptor ... See full document
9
Genetic, environmental and stochastic factors in monozygotic twin discordance with a focus on epigenetic differences
... in DNA methylation discordance in ...cal methylation levels ...DZ twins pairs at birth, and analysed them for CpG methylation at four differentially methylated regions (DMRs) ... See full document
12
DNA Methylation Changes in the IGF1R Gene in Birth Weight Discordant Adult Monozygotic Twins
... whole blood samples of extreme birth weight discordant MZ twin ...IGF1R methylation and birth weight ratio (random-effects meta-analysis p = ...older twins. Although DNA methyla- tion profiles ... See full document
12
Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits
... MZ twins represents a powerful strategy in epigenetic epidemiology because identical twins are matched for genotype, age, sex, maternal environment, population cohort effects and exposure to many shared ... See full document
10
DNA methylation differences in monozygotic twin pairs discordant for schizophrenia identifies psychosis related genes and networks
... Interestingly, methylation differences between identical twins have been reported as early as in newborns ...[10]. DNA methylation is reported to increase with age [11] and accordingly, ... See full document
12
Genetic factors underlying discordance in chromatin accessibility between monozygotic twins
... on differences in DNA methylation ...genetic differences between multiple MZ twins and exam- ine their linkage with chromatin discordance and differen- tial ...genetic ... See full document
13
Impact of Early Environment on Children's Mental Health: Lessons From DNA Methylation Studies With Monozygotic Twins
... epigenome-wide DNA methylation in MZ twins have been published (Gordon et ...adult twins with methylation data from saliva sam- ...and DNA methylation that survived ... See full document
12
Aging as Accelerated Accumulation of Somatic Variants: Whole-Genome Sequencing of Centenarian and Middle-Aged Monozygotic Twin Pairs
... somatic DNA mutations and that subsequent errors in the primary structure of proteins ultimately reach levels sufficient to affect organismal ...of DNA in whole blood of two pairs of ... See full document
7
Genetic Inheritance in Non-Syndromic Infantile Esotropia
... AHI1 is a component of a protein complex in the cellular basal body, a ring-like structure that plays a role in the transition zone at the base of cilia. This complex acts as a barrier to restrict protein diffusion ... See full document
5
Epigenomic analysis of lung adenocarcinoma reveals novel DNA methylation patterns associated with smoking
... with lung cancer but not in nonsmokers with lung cancer in this ...variants associated with the risk of lung cancer in the NNK disposition pathways, such as CYP2A13, the most active P450 for ... See full document
9
Congenital Hydranencephaly/Porencephaly Due to Vascular Disruption in Monozygotic Twins
... The additional finding that 75% of cases were associated with a deceased co-twin may be important in understanding the relationship be- tween monozygotic twins and hydranencephaly/ poren[r] ... See full document
5
What Do Studies of Insect Polyphenisms Tell Us about Nutritionally-Triggered Epigenomic Changes and Their Consequences?
... Polyphenisms are where two or more distinct phenotypes are produced from a single genotype. Perhaps the best-known case of this is caste development in honeybees. Honeybees have two female castes, workers and queens. ... See full document
11
One CNV Discordance in NRXN1 Observed Upon Genome-wide Screening in 38 Pairs of Adult Healthy Monozygotic Twins
... One motivation for searching for MZ genotype dif- ferences is that they might explain MZ phenotypic dis- cordances and in turn provide a ‘shortcut’ to functional variants. Thus, identification of genetic mismatches in MZ ... See full document
7
Alu and LINE-1 methylation and lung function in the normative ageing study
... is associated with increased age, 8 37 greater alcohol use and gender (lower in ...been associated with higher incidence of cancer in general and lung cancer speci fi cally (LINE-1 ... See full document
8
Do MZ twins have discordant experiences of friendship? : A qualitative hypothesis-generating MZ twin differences study
... MZ twins report discordant peer relationships and, if so, whether they perceive them as causes, consequences or correlates of discordant ...of discordance were identified (peer victimisation, peer ... See full document
82
Effects of Intrauterine Environment on the Magnitude of Differences Within the Pairs of Monozygotic and Dizygotic Twins
... of differences within the pairs of ...that monozygotic (MZ) twins are genetically identical and dizygotic (DZ) twins are re- lated to the same degree as any other ... See full document
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