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[PDF] Top 20 Mesenchymal stem cells in osteoarticular diseases: an update

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Mesenchymal stem cells in osteoarticular diseases: an update

Mesenchymal stem cells in osteoarticular diseases: an update

... using cells embedded in scaffolds combined with growth factors or using beads releasing ...rheumatic diseases for which currently available treatments are limited and rarely restore the full functions of ... See full document

10

Mesenchymal stem cells (MSCs) as skeletal therapeutics–an update

Mesenchymal stem cells (MSCs) as skeletal therapeutics–an update

... and subsequent injection under the periosteal flap. Data demonstrated significant repair of the tissue along with pain reduction and restoration of joint function [98]. With this promising clinical finding, several other ... See full document

15

Characterization and Therapeutic Application of Mesenchymal Stem Cells with Neuromesodermal Origin from Human Pluripotent Stem Cells

Characterization and Therapeutic Application of Mesenchymal Stem Cells with Neuromesodermal Origin from Human Pluripotent Stem Cells

... Mesenchymal stem cells (MSC) hold great therapeutic potential for cell-based tissue engineering and regenerative medicine, as they offer the benefits of easy isolation, multipotency, paracrine ... See full document

15

Transplantation of induced pluripotent stem cell-derived mesenchymal stem cells improved erectile dysfunction induced by cavernous nerve injury

Transplantation of induced pluripotent stem cell-derived mesenchymal stem cells improved erectile dysfunction induced by cavernous nerve injury

... pluripotent stem cells (iPSC) are pluripotent stem cells generated by reprogramming somatic cells ...pluripotent stem cell-derived mesenchymal stem cells, ... See full document

15

Stem cell therapy for retinal diseases: update

Stem cell therapy for retinal diseases: update

... Distinct stem cell types have been established from embryos and identifi ed in the fetal tissues and umbilical cord blood as well as in specifi c niches in many adult mammalian tissues and organs such as bone ... See full document

10

Exosomes in Mesenchymal Stem Cells, a New Therapeutic Strategy for Cardiovascular Diseases?

Exosomes in Mesenchymal Stem Cells, a New Therapeutic Strategy for Cardiovascular Diseases?

... The above studies reveal that MSCs-derived ex- osomes play an essential role in MSCs-based therapy of CVDs including MI, reperfusion injury and PH. The detailed mechanisms underlying benefits of exo- somes in MSCs ... See full document

8

Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity

Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity

... liver diseases [7, ...context, mesenchymal stem cells (MSC) are promis- ing candidates for cell therapy because of their multipo- tent differentiation ability and immunomodulatory activity ... See full document

14

Clinical trials using mesenchymal stem cells in liver diseases and inflammatory bowel diseases

Clinical trials using mesenchymal stem cells in liver diseases and inflammatory bowel diseases

... Th1 cells are associated with the pathogenesis of CD ...Th17 cells are present in both UC and CD. Thus, mucosal CD4+ T cells are key mediators of the driving response ... See full document

15

Comparative analysis of curative effect of bone marrow mesenchymal stem cell and bone marrow mononuclear cell transplantation for spastic cerebral palsy

Comparative analysis of curative effect of bone marrow mesenchymal stem cell and bone marrow mononuclear cell transplantation for spastic cerebral palsy

... that stem cell transplantation in the treatment of traumatic brain injury [12], cerebral haemorrhage [15], stroke [16], spi- nal cord injury [17], ataxia [5, 18, 19] and many other kinds of diseases of the ... See full document

9

Mesenchymal stem cells for treating ocular surface diseases

Mesenchymal stem cells for treating ocular surface diseases

... MPS VII, also known as Sly syndrome, is a lysosomal storage disease. It is an autosomal recessive inherited disease caused by a mutation in the GUSB gene coding β-glucuronidase [54–56]. The deficiency of the ... See full document

11

Mesenchymal stem cells in arthritic diseases

Mesenchymal stem cells in arthritic diseases

... Mesenchymal stem cells (MSCs), the nonhematopoietic progenitor cells found in various adult tissues, are characterized by their ease of isolation and their rapid growth in vitro while ... See full document

12

Human endometrial mesenchymal stem cells restore ovarian function through improving the renewal of germline stem cells in a mouse model of premature ovarian failure

Human endometrial mesenchymal stem cells restore ovarian function through improving the renewal of germline stem cells in a mouse model of premature ovarian failure

... novel stem cell source has the superiority to conventional ...mal stem cells (EnSCs) with mesenchymal stem/stromal cells (MSCs) characteristics have been isolated from menstrual ... See full document

13

Optimal Dose and Timing of Umbilical Stem Cells Treatment in Pulmonary Arterial Hypertensive Rats

Optimal Dose and Timing of Umbilical Stem Cells Treatment in Pulmonary Arterial Hypertensive Rats

... cells/rat (UC group) in MCT-induced PAH rats. Thus, the hUCB-MSCs were diluted in 500 μL of Dulbecco’s modified Ea- gle’s medium and were directly administered into the external jugular vein of rats placed in a ... See full document

11

Mesenchymal stem cells combined with liraglutide relieve acute lung injury through apoptotic signaling restrained by PKA/β-catenin

Mesenchymal stem cells combined with liraglutide relieve acute lung injury through apoptotic signaling restrained by PKA/β-catenin

... Recently, using of mesenchymal stem cells (MSCs) in the treatment of ALI has proven to be effective [13]. They se- crete paracrine factors that regulate lung endothelial and epithelial permeability, ... See full document

16

Mesenchymal stem cell derived hematopoietic cells are permissive to HIV 1 infection

Mesenchymal stem cell derived hematopoietic cells are permissive to HIV 1 infection

... HUT78-HIV cells, there were sev- eral other salient differences in the gene expression pro- files following HIV-1 ...HD cells, HIV-1 infection altered the expression of genes associated with apoptosis such ... See full document

12

Crosstalk between stem cell and spinal cord injury: pathophysiology and treatment strategies

Crosstalk between stem cell and spinal cord injury: pathophysiology and treatment strategies

... transplanted into the contused, crushed, or transverse wounded spinal cords [24]. The main BM-MSC trans- plantation methods that are currently used include in situ injection, intravenous injection, intrathecal injection, ... See full document

13

Systemic administration of a novel human umbilical cord mesenchymal stem cells population accelerates the resolution of acute liver injury

Systemic administration of a novel human umbilical cord mesenchymal stem cells population accelerates the resolution of acute liver injury

... To assess the differences between the three supports considered in our study we performed a multiple com- parison of the expression levels of each marker analyzed and the albumin secretion at each time point. This ana- ... See full document

16

Effect of Bone Marrow Stem Cells on the Healing of Colonic Anastomosis in Rats

Effect of Bone Marrow Stem Cells on the Healing of Colonic Anastomosis in Rats

... longer and will be more pronounced. After 1–2 wks, the epithelial layer is fully reestablished over a granulomatous notch consisting of proliferating smooth muscle cells and fibroblasts. Reconstitution of the ... See full document

59

Mesenchymal and induced pluripotent stem cells: general insights and clinical perspectives

Mesenchymal and induced pluripotent stem cells: general insights and clinical perspectives

... iPS cells have particular characteristics (Table ...ideal stem cell for transplantation should be immunologically inert, derived from sources easily accessible, with high and fast expansion in vitro, ... See full document

10

Adipose Tissue and Bone Marrow-Derived Mesenchymal Stem Cells Role in Regeneration of Cleft Alveolus in Dogs

Adipose Tissue and Bone Marrow-Derived Mesenchymal Stem Cells Role in Regeneration of Cleft Alveolus in Dogs

... All the animals were observed daily and followed up for any post-surgical edema or infection, adverse or allergic reactions due to the placement of the stem cells. Ten % IM gentamicin antibiotic (Gibco/BRL, ... See full document

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