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[PDF] Top 20 1 (4 Meth­oxy­phenyl) 2 (2 nitro­phen­oxy)­propan 1 one

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1 (4 Meth­oxy­phenyl) 2 (2 nitro­phen­oxy)­propan 1 one

1 (4 Meth­oxy­phenyl) 2 (2 nitro­phen­oxy)­propan 1 one

... The parameters of the non-classical intermolecular CÐ H O hydrogen bonds (Gu et al., 1999) in (II) are given in Table 2. The H atoms on atoms C3 and C7 are involved in two intermolecular hydrogen bonds as donors, ... See full document

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1 (4 Meth­oxy­phenyl) 2 (6 methyl 2 nitro 3 pyridyl­oxy)propan 1 one

1 (4 Meth­oxy­phenyl) 2 (6 methyl 2 nitro 3 pyridyl­oxy)propan 1 one

... aromatic rings, but with different substituents. No signi®cant differences were found in the bond distances and angles of the two molecules, except that, in the case of (III), keto atom O4 is 0.201 (5) AÊ out of the ... See full document

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3 (4 Meth­oxy­phenyl) 1 phenyl 3 (p toluene­sulfonyl­amino)­propan 1 one

3 (4 Meth­oxy­phenyl) 1 phenyl 3 (p toluene­sulfonyl­amino)­propan 1 one

... ±Aminoketones are important synthetic intermediates in organic synthesis and are almost always generated by the Mannich reaction (Miura & Tamaki, 2000; Ranu et al., 2002). In our laboratory, we have recently ... See full document

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3 (4 Chloro­phenyl) 1 phenyl 3 (p tolyl­sulfonyl­amino)­propan 1 one

3 (4 Chloro­phenyl) 1 phenyl 3 (p tolyl­sulfonyl­amino)­propan 1 one

... The addition of nucleophilic reagents to unsaturated carbon± nitrogen bonds is a common practice in the synthesis of amine derivatives (Kobayashi & Ishitani, 1999). In our laboratory, we have recently investigated a ... See full document

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Crystal structure of 3 (morpholin 4 yl) 1 phenyl 3 (pyridin 2 yl)propan 1 one

Crystal structure of 3 (morpholin 4 yl) 1 phenyl 3 (pyridin 2 yl)propan 1 one

... To an ethanolic solution of acetophenone (3.0 ml, 0.025 mol) taken in a round bottom flask, morpholine (2.1 ml, 0.025 mol) and pyridine-2-carboldehyde (2.6 ml, 0.025 mol) were added. The reaction mixture was kept ... See full document

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2 (6 Meth­­oxy­naphthalen 2 yl) 1 (morpholin 4 yl)propan 1 one

2 (6 Meth­­oxy­naphthalen 2 yl) 1 (morpholin 4 yl)propan 1 one

... C7 0.046 (2) 0.040 (2) 0.067 (3) −0.004 (2) −0.003 (2) 0.007 (2) C8 0.052 (3) 0.054 (3) 0.054 (3) −0.009 (2) 0.004 (2) 0.006 (2) C9 0.044 (2) 0.049 (3) 0.056 ... See full document

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2 [4 (2 Chloro­acet­yl)phen­yl] 2 methyl 1 (pyrrolidin 1 yl)propan 1 one

2 [4 (2 Chloro­acet­yl)phen­yl] 2 methyl 1 (pyrrolidin 1 yl)propan 1 one

... C19 0.086 (6) 0.083 (6) 0.145 (8) 0.016 (5) 0.046 (6) 0.041 (6) C20 0.060 (4) 0.038 (4) 0.130 (7) −0.003 (3) 0.027 (4) 0.019 (4) C21 0.053 (3) 0.031 (3) 0.042 (3) −0.001 (3) 0.005 (3) 0.001 ... See full document

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2,3 Di­bromo 3 (4 chloro­phen­yl) 1 (4 nitro­thio­phen 2 yl)propan 1 one

2,3 Di­bromo 3 (4 chloro­phen­yl) 1 (4 nitro­thio­phen 2 yl)propan 1 one

... ecule disorder over two orientations in a 0.805 (6):0.195 (6) ratio. The dihedral angles between the thiophene ring [maximum deviations = 0.017 (4) and 0.033 (9) A ˚ for the major and minor components, ... See full document

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2 Methyl 2 phenyl 1 (pyrrolidin 1 yl)propan 1 one

2 Methyl 2 phenyl 1 (pyrrolidin 1 yl)propan 1 one

... O1 0.0851 (15) 0.0855 (15) 0.0406 (11) 0.0132 (12) −0.0194 (10) −0.0072 (11) N1 0.0442 (13) 0.0590 (15) 0.0403 (12) 0.0075 (11) −0.0073 (9) 0.0037 (11) C1 0.079 (2) 0.0611 (19) 0.0433 (16) 0.0133 (17) −0.0134 (14) ... See full document

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2 (4 Iso­butyl­phen­yl) 1 (morpholin 4 yl)propan 1 one

2 (4 Iso­butyl­phen­yl) 1 (morpholin 4 yl)propan 1 one

... Data collection: APEX2 Bruker, 2009; cell refinement: SAINT Bruker, 2009; data reduction: SAINT; programs used to solve structure: SHELXS97 Sheldrick, 2008; programs used to refine struc[r] ... See full document

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SYNTHESIS, CHARACTERIZATION AND ANTITUBERCULAR ACTIVITY OF NOVEL2, 5 DIMETHYL 4 (ARYL OR HETERO ARYL) SUBSTITUTED ANILINE 1, 3 OXAZOLE DERIVATIVES

SYNTHESIS, CHARACTERIZATION AND ANTITUBERCULAR ACTIVITY OF NOVEL2, 5 DIMETHYL 4 (ARYL OR HETERO ARYL) SUBSTITUTED ANILINE 1, 3 OXAZOLE DERIVATIVES

... novel 2, 5-dimethyl-4-(aryl or hetero aryl) substituted aniline-1,3- oxazole derivatives in three steps, using 2-bromo-1-(4-bromophenyl)propan-1-one, acetamide and ... See full document

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Synthesis of some new 1 N  (β  D glucopyranosyl) 2 ((1 phenyl 5 aryl) pyrazol 3 yl) pyrroles and their biological activities

Synthesis of some new 1 N (β D glucopyranosyl) 2 ((1 phenyl 5 aryl) pyrazol 3 yl) pyrroles and their biological activities

... yield 2-((3-aryl) propan-1- one) pyrroles 1, which on cyclization with phenyl hydrazine gives 2-((1-phenyl, 5-aryl)-pyrazol- 3-yl) pyrroles ...of 2, ... See full document

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Crystal structure of (2R) 1 [(methyl­sulfon­yl)­­oxy]propan 2 aminium chloride: a chiral mol­ecular salt

Crystal structure of (2R) 1 [(methyl­sulfon­yl)­­oxy]propan 2 aminium chloride: a chiral mol­ecular salt

... The title chiral molecular salt was synthesised as per the literature procedure (Higashiura et al., 1989). An aqueous solution of HCl (4 M, 12 ml) was added to a stirred solution of ... See full document

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2 [(3 Oxo 1 benzo­furan 6 yl)­­oxy]aceto­nitrile

2 [(3 Oxo 1 benzo­furan 6 yl)­­oxy]aceto­nitrile

... As a continuation of our progress in the development of hybrid drug candidates against tuberculosis, malaria and cancer (Morphy et al., 2004), the title compound was identified as a promising starting material. The ... See full document

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(E) 1 Eth­oxy­carbonyl 2 [(2 hy­droxy 1 naphthyl)(phenyl)methyliminio]propan 1 ide

(E) 1 Eth­oxy­carbonyl 2 [(2 hy­droxy 1 naphthyl)(phenyl)methyliminio]propan 1 ide

... O31 0.0361 (5) 0.0358 (5) 0.0649 (7) −0.0002 (4) 0.0212 (4) 0.0090 (5) O32 0.0430 (5) 0.0488 (6) 0.0568 (6) −0.0030 (4) 0.0077 (4) 0.0186 (5) O33 0.0670 (7) 0.0640 (8) 0.0522 (7) 0.0004 (6) ... See full document

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(Z) 1 Chloro 1 [2 (2 nitro­phen­yl)hydrazinyl­­idene]propan 2 one

(Z) 1 Chloro 1 [2 (2 nitro­phen­yl)hydrazinyl­­idene]propan 2 one

... 2-Nitroaniline (0.1 mol) was dissolved in cold aqueous hydrochloric acid (80 ml, 5 N). To this solution was added dropwise a solution of sodium nitrite (7.6 g, 0.1 mol) in water (25 ml) with efficient stirring at ... See full document

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1 Methyl­ethyl 2 [(1 bromo 2 naphthyl)­­oxy]­ethano­ate

1 Methyl­ethyl 2 [(1 bromo 2 naphthyl)­­oxy]­ethano­ate

... cold 2-propanol (50 ml) with stirring and left for 2 ...silica. 1-Methylethyl 2-[(1-bromo-2-naphthyl)- oxy]ethanoate was recrystallized from 2-propanol; ...a ... See full document

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(2E) 1 (4 Chloro­phen­yl) 3 [4 (propan 2 yl)phen­yl]prop 2 en 1 one

(2E) 1 (4 Chloro­phen­yl) 3 [4 (propan 2 yl)phen­yl]prop 2 en 1 one

... Cl1 0.0684 (8) 0.0788 (8) 0.1002 (10) −0.0040 (5) 0.0173 (6) 0.0148 (6) O1 0.0799 (19) 0.0492 (16) 0.0811 (19) −0.0082 (14) 0.0161 (15) −0.0158 (14) C1 0.064 (2) 0.053 (2) 0.061 (2) −0.0177 (17) ... See full document

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Synthesis and in vitro antitumor activity of (1E,4E)-1-aryl-5-(2-((quinazolin-4-yl)oxy)phenyl)-1,4-pentadien-3-one derivatives

Synthesis and in vitro antitumor activity of (1E,4E)-1-aryl-5-(2-((quinazolin-4-yl)oxy)phenyl)-1,4-pentadien-3-one derivatives

... The in vitro antitumor activity of the newly synthesized compounds 5a–5n were evaluated against a panel of three human cancer cell lines, including human gastric cancer cell line MGC-803, human prostate cancer cell line ... See full document

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1 (2 Methyl 5 nitro 1H imidazol 1 yl)propan 2 yl acetate

1 (2 Methyl 5 nitro 1H imidazol 1 yl)propan 2 yl acetate

... The title compound (I) is an ester derivative of well known 5-nitroimidazole drug i.e secnidazole. The worthwhile use of nitroimidazole derivatives is in the treatment of diseases caused by protozoa and anaerobic ... See full document

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