[PDF] Top 20 1 Methyl 6 nitro 1H benzimidazole
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1 Methyl 6 nitro 1H benzimidazole
... the plane of the heterocycle. The bond lengths in the present derivative were analyzed in details and compared with those of the parent unsubstituted analogues in the Cambridge Structural Database. The results have shown ... See full document
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2 (3 Methyl 2 nitrophenyl) 1H benzimidazole
... We have reported the structure of 2-(2-nitrophenyl)-1H- benzimidazole, (II) (Li et al., 2005). In order to investigate the effect of the substituent on the molecular conformation, the title compound, (I), ... See full document
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1 (5,6 Dimethyl 1,2,4 triazin 3 yl) 2 methyl 1H benzimidazole
... C1 0.0454 (7) 0.0519 (8) 0.0374 (7) −0.0030 (6) 0.0011 (6) −0.0012 (6) C2 0.0546 (9) 0.0505 (9) 0.0596 (9) −0.0040 (7) 0.0029 (7) −0.0181 (8) C3 0.0633 (10) 0.0411 (8) 0.0788 (12) −0.0003 (7) 0.0060 ... See full document
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6 Nitro 2 propyl 1H indole
... The title compound was synthesized by a modi®cation of the method previously described for the Sonogashira coupling reaction (Rodri- guez et al., 2000) of 2-amino-3-nitrophenol and 1-n-pentaacetylene under the ... See full document
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Dibromidobis(2 methyl 1H benzimidazole κN3)cadmium
... atom has a distorted tetrahedral coordination formed by the two imino N atoms of two 2-methylbenzimidazole ligands and two terminal bromide ligands. The Cd II atom is slightly out of the benzimidazole planes by ... See full document
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Diaquabis(5 nitro 1H benzimidazole κN3)copper(II) dinitrate
... inversion centre, is four-coordinated by the two O atoms from two water molecules and two N atoms from two benzimidazole ligands (Fig. 1). The geometry around the Cu atom is nearly perfect square planar, ... See full document
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DEVELOPMENT AND VALIDATION OF HPLC METHOD FOR THE DETERMINATION OF METRONIDAZOLE BENZOATE AND RELATED IMPURITES IN BULK AND PHARMACEUTICAL FORMULATIONS
... The different pharmacopoeias, such as the BP and USP, are slowly incorporating limits to allowable levels of impurities present in the APIs or formulations. Moreover, literature survey reveals that, metronidazole ... See full document
6
Crystal structure of 3 chloro 1 methyl 5 nitro 1H indazole
... C3 0.0266 (8) 0.0304 (8) 0.0285 (7) −0.0028 (6) 0.0056 (6) −0.0032 (6) C4 0.0270 (8) 0.0348 (8) 0.0284 (7) −0.0043 (6) 0.0051 (6) −0.0020 (6) C2 0.0310 (8) 0.0321 (8) 0.0276 (7) ... See full document
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1 Methyl 4 nitro 1H imidazole 2 carboxylic acid dihydrate
... A small quantity of the ethyl ester of the title carboxylic acid (Wu et al., 2004) was suspended in lithium hydroxide solution (0.1 M) and tetrahydrofuran (THF) was added until it dissolved; the water/THF ratio was ... See full document
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1 Methyl N (2 {[(1 methyl 4 nitro 1H pyrrol 2 yl)carbonyl]amino}ethyl) 4 nitro 1H pyrrole 2 carboxamide dimethylformamide disolvate
... N1 0.0315 (17) 0.0252 (17) 0.0278 (17) −0.0125 (14) −0.0013 (13) 0.0009 (14) O3 0.054 (2) 0.0448 (18) 0.0339 (18) −0.0094 (15) −0.0017 (14) −0.0099 (14) C6 0.025 (2) 0.037 (2) 0.034 (2) −0.0189 (17) 0.0017 (16) −0.0090 ... See full document
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2 (2 Methyl 5 nitro 1H imidazol 1 yl)ethyl methanesulfonate
... The title compound contains two independent molecules in an asymmetric unit (Fig. 1) with identical conformations. The two imidazole rings (C2—C4/N2/N3 and C9—C11/N5/N7) are individually planar with r.m.s.d's ... See full document
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1 Benzyl 2 [1 (5 methyl 1H pyrazol 3 yl) 2 phenylethyl]benzimidazole
... Hydrazine hydrate (0.29 cc, 0.006 mol) was added to a solution of (4Z)-(2-oxopropylidene)-1,3-dibenzyl-1,2,4,5-tetrahydro-2H-1,5- benzodiazepin-2-one (1.17 g, 0.003 mol) in ethanol (30 ml). The reaction mixture was ... See full document
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(E) N′ (2 Chlorobenzylidene) 1 methyl 4 nitro 1H pyrrole 2 carbohydrazide
... Cl1 0.1002 (9) 0.0517 (6) 0.1730 (14) 0.0028 (6) 0.0731 (9) −0.0179 (7) N1 0.0553 (16) 0.0427 (14) 0.0560 (18) −0.0065 (13) 0.0130 (13) 0.0045 (13) N2 0.057 (2) 0.102 (3) 0.057 (2) −0.019 (2) 0.0189 (16) ... See full document
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3 Nitro 1 (phenylsulfonyl) 1H indole
... C12 0.0140 (5) 0.0195 (6) 0.0242 (6) −0.0024 (4) 0.0047 (5) −0.0052 (4) C13 0.0171 (5) 0.0197 (5) 0.0205 (5) 0.0021 (4) 0.0004 (5) −0.0059 (4) C14 0.0215 (6) 0.0217 (6) 0.0131 (5) 0.0052 (4) ... See full document
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Ethyl 3 methyl 5 nitro 1H imidazole 2 carboxylate
... (Fig. 1), (I), is a reagent that is used for the synthesis of the analogs of netropsin and distamycin, which represent a class of extremely potent anti-cancer compounds having an imidazole unit in the molecular ... See full document
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Crystal structure of 1 [(1 methyl 5 nitro 1H imidazol 2 yl)methyl]pyridinium iodide
... C1 0.0291 (8) 0.0313 (8) 0.0262 (7) −0.0053 (6) 0.0025 (6) 0.0001 (6) C2 0.0322 (10) 0.0468 (11) 0.0620 (12) 0.0067 (8) 0.0072 (9) −0.0108 (9) C3 0.0317 (8) 0.0315 (8) 0.0268 (7) −0.0030 (6) ... See full document
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2 (2 Methyl 5 nitro 1H imidazol 1 yl)ethyl N methylcarbamate
... O2 0.0506 (7) 0.0844 (9) 0.0671 (8) −0.0186 (6) −0.0026 (6) −0.0062 (7) O3 0.0351 (5) 0.0590 (7) 0.0568 (7) −0.0004 (5) 0.0146 (5) 0.0064 (5) O4 0.0431 (6) 0.0645 (7) 0.0486 (6) −0.0100 (5) ... See full document
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4 Methylacetophenone [(2 methyl 4 nitro 1H imidazol 1 yl)acetyl]hydrazone
... The imidazole nucleus appears in a number of naturally occurring products, among which the most important are the amino acid histidine and the base purine. Imidazole deriva- tives exhibit a broad spectrum of ... See full document
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4 Dimethylamino 6 (1 methyl 4 nitro 1H pyrrol 2 yl) 1,3,5 triazine 2 amine dimethylformamide solvate
... The main geometric parameters of (I) are listed in Table 1 and the molecular structure is illustrated in Fig. 1. Compound (I) contains a pyrrole and a triazine ring, which are connected by a C2ÐC6 bond of ... See full document
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1 (2,6 Diisopropylphenyl) 1H benzimidazole
... N-(2-bromophenyl)-N′-(2, 6-diisopropylphenyl)-Methanimidamide, (1.65 g, 4.58 mmol, 1 eq.) was dissolved in 18.5 ml DMSO. CuI (174 mg, 0.92 mmol, 20 mol%) and DBU (1.37 ml, 1.39 g, 9.16 mmol, 2 eq.) were ... See full document
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