[PDF] Top 20 Microfluidic Technologies for High-Throughput Screening Applications
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Microfluidic Technologies for High-Throughput Screening Applications
... two microfluidic channels containing water and an oil surfactant ...by high shear forces generated at the leading edge of the water perpendicular to the oil flow, generating picoliter-scale ... See full document
180
Development of Gel Droplet Microfluidic System for High Throughput Microbial Screening
... 1.2.3 Synthetic polymers PEG (polyethylene glycol) is a biocompatible and biodegradable hydrophilic poly- meric network chains comprising a PEG diol with two hydroxyl end groups that can be changed into other groups to ... See full document
53
A microfluidic spheroid culture device with a concentration gradient generator for high-throughput screening of drug efficacy
... maintained high-cell viability. In the past, numerous microfluidic platforms have been designed for formation of spheroids using microwells or U-shaped microstructures in the ...Microwell-based ... See full document
9
An integrated droplet based microfluidic platform for high throughput, multi-parameter screening of photosensitiser activity
... the microfluidic channel ...between microfluidic measurements depending on the surface pre-treatment, device operation time, the concentration of SYTO-9, device material and laser ...this, ... See full document
224
Droplet-based microfluidic high-throughput screening of heterologous enzymes secreted by the yeast Yarrowia lipolytica
... enzymatic high‑throughput screening (HTS), especially for exploring large diversities with lower time and cost ...droplet‑based microfluidic HTS system was developed to (a) encapsulate single ... See full document
14
Applications of Support Vector Machines as a Robust tool in High Throughput Virtual Screening
... A number of efforts were expended to select the optimum scaffold and the activities of the predicted actives by SVM were estimated by using the MLRS model. Jorgenson group at University of Copenhagen developed many ... See full document
13
Photobioreactor Technologies for High-throughput Microalgae Cultivation
... The biochemical composition of different strains of microalgae has been extensively studied due to the various applications of algal biomass and metabolites (Guedes et al., 2011). This knowledge enhances strain ... See full document
189
Indices and Applications in High-Throughput Sequencing
... Table 1.1: Approximate run times, yields, read lengths, costs, and sequencing error rates of different high-throughput sequencing technologies by mid 2011 [Glenn, 2011]. and dehybridized into two ... See full document
208
Bacterial Microcolonies in Gel Beads for High-throughput Screening.
... render them hydrophobic (Devenish et al., 2013). The design file of the device used in this study (40 µm flow-focusing channel) is available from the author’s website: (Figure 1). Figure 1. Design of the ... See full document
15
High-Throughput Screening for Phase-Change Memory Materials
... Yu-Ting Liu, Xian-Bin Li,* Hui Zheng, Nian-Ke Chen,* Xue-Peng Wang, Xu-Lin Zhang, Hong-Bo Sun,* and Shengbai Zhang Phase change memory (PCM) is an emerging non-volatile data storage technology concerned by the ... See full document
11
Therapy response testing of breast cancer in a 3D high-throughput perfused microfluidic platform
... A significant amount of work lies ahead in which we will test and evaluate primary patient biopsies in the Organo- Plate®, assess their longevity and retrospectively compare drug response to clinical outcome. Critical ... See full document
11
Clinical application of high throughput molecular screening techniques for pharmacogenomics
... CYP2D6 genotyping for multiple drug metabolism The CYP450 enzyme system is one of the most important determinants of drug metabolism in humans. One of the central components of this pathway is the enzyme encoded by the ... See full document
13
Development of a high throughput cell-free metagenomic screening platform
... 161 Lignocellulases are required for a wide range of applications, including the production of biofuels. While the production of biofuels from the renewable lignocellulosic biomass is gradually considered a ... See full document
223
Statistical models for identifying frequent hitters in high throughput screening
... High Throughput Screening (HTS) has been used for over a quarter century to identify new drug candidates 1 ...instrumental technologies of HTS have been influential for increasing the scale ... See full document
13
A high-throughput cellulase screening system based on droplet microfluidics
... A new ultra-high-throughput screening assay for the detection of cellulase activity was developed based on microfluidic sorting. Cellulase activity is detected using a series of coupled ... See full document
5
High-Throughput Screening in Protein Engineering:Recent Advances and Future Perspectives
... first microfluidic device, an aqueous suspension of bacterial cells expressing the enzyme of interest is mixed together with a second aqueous stream at a flow-focusing ...second microfluidic device, where ... See full document
29
High Throughput Screening (HTS) - Global Strategic Business Report
... Robotic High Speed Screening System II-28 Life Technologies Introduces TaqMan OpenArray MicroRNA Panels II-28 Zyleris Introduces Screening Service for Drug Development II-28 Genosphere ... See full document
8
Metaphor-Based Design of High-Throughput Screening Process Interfaces
... particular screening method editor displays and action sequences led to the information operators needed for certain process ...software applications used in the HTS process at CELISCA (Kaber et ... See full document
21
High-throughput screening of Mucoromycota fungi for production of low- and high-value lipids
... and high-value ...biotechnological applications is the selec- tion of suitable strains for lipid ...for high-throughput screening of the potential of 100 Mucoromycota strains to produce ... See full document
17
High-throughput high-volume nuclear imaging for preclinical in vivo compound screening§
... Multi-atlas segmentation has proven useful for auto- mated region identification especially in clinical neuro- applications [24–27]. To overcome the limitation of many available software packages designed for ... See full document
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