[PDF] Top 20 MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells

... the expression of nuclear factor I/B (NFIB), one of miR-302c targeted genes, was repressed in hES cells and upregulated in EB and adult ...chondrocytic differentiation [79] and lung develop- ment ... See full document

... TF expression in G-M cells and trophoblasts but not through the Erk1/2 pathway Both miR-20b and the Erk1/2 signaling pathway regulated TF expression in G-M cells and ...the expression ... See full document

... and differentiation of embryonic stem ...in human neurons and cancer cells and in several tissues in mouse, including pluripotent stem ...about human moRNAs and their ... See full document

... hepatic differentiation of HLCs Fuzzy clustering of 10,420 differentially expressed genes in hESCs and HLCs generated 20 distinct clusters that represent well-defined gene expression ... See full document

... culture, human embryonic stem (hES) cells undergo adaptation, exhibiting decreased population doubling times and increased cloning efficiencies, often associ- ated with karyotypic ...the ... See full document

... CPA4 expression to a greater extent than TSA in the most basal and non-malignant cell lines (PNT2-C2 and P4E6), whereas TSA had a larger effect on the more differentiated and malignant cell lines (PC3 and ...CPA4 ... See full document

... marker gene expression profiles between individual EBs of homogeneous cell number and size, which origi- nated from two tissue culture ...of differentiation protocols that yield more uniform ... See full document

... multinucleate cells and significantly reduced the formation of mesenchymal cells, but did not abolish ...epithelial cells that were seen to remain in these conditions, for the presence of CDX2 and ... See full document

... the differentiation process and the multiple targets that have been proposed for SETD7 (Fig 5E) a more systematic approach will be needed in the future to dissect the specific effects of SETD7 on H1 ...during ... See full document

... in human neuronal develop- ment and play critical roles in human NPC proliferation and migration ( Wu et ...in human NSCs. Besides, we observed a dramatic increase in CXCR4 expression during ... See full document

... therapy. Human embryonic stem cell (hESC) lines were investigated as a model for parathyroid regeneration in ...on expression of genes of interest in embryoid bodies ...mouse embryonic ... See full document

... entire gene body and regions beyond, which is in contrast to a typical UMR (CLMN, Figure 5 ...H1-derived cells ( Figures S5 A and 5 B), we identified those that are at least 5 kb long, which constitute less ... See full document

... by gene expression during in vitro mouse ES cells differentiation, an early marker such as TTR was detected within 3 days after induction of ...endodermal differentiation as well as an ... See full document

... Vitro Differentiation Group, IPK Gatersleben, Germany ABSTRACT The effects of lithium chloride (LiCl) on differentiation of mouse embryonic stem (ES) cells were investigated in order to ... See full document

... of Stem Cell Biology, Graduate School of Medical Science and 2 Department of Stem Cell Medicine, Cancer Research Institute, Kanazawa University, Kanazawa, Japan ABSTRACT Embryonic stem (ES) ... See full document

... ES cells depending on their expression status. While its expression in the mitotic phase indicates that miR-137 is involved in cell division, increased levels of the miRNA during ... See full document

... developmental gene expression (Pasini, Bracken et ...premature expression of differentiation ...repress differentiation gene expression in a flexible manner, which can be ... See full document

... S2 Differentiation of H7 control and ...the expression of Foxa2, a marker of definitive endoderm which persists during pancreatic ...glucagon gene was upregulated in 2/3 H7.Px4 clones during ... See full document

... spa-1 gene was activated in undifferentiated hESCs compared to differenti- ated hESCs, and have demonstrated in the present study that spa-1 signaling is needed for the maintenance of ... See full document

... WT Expression Kit (Ambion) and Gene- Chip  WT Terminal Labeling and Controls Kit (Affymetrix) were used according to the manufacturer’s instructions for target preparation on the Affymetrix  Mouse ... See full document