[PDF] Top 20 Minimum Requirements for the Function of Eukaryotic Translation Initiation Factor 2
Has 10000 "Minimum Requirements for the Function of Eukaryotic Translation Initiation Factor 2" found on our website. Below are the top 20 most common "Minimum Requirements for the Function of Eukaryotic Translation Initiation Factor 2".
Minimum Requirements for the Function of Eukaryotic Translation Initiation Factor 2
... capped eukaryotic messenger RNAs in a process that highly similar to eubacterial elongation factor EF1A appears to involve interactions between eIF3 and pro- (formerly EF-Tu; Hannig et ... See full document
10
Cell-Type-Specific Growth Restriction of Vesicular Stomatitis Virus polR Mutants Is Linked to Defective Viral Polymerase Function
... of eukaryotic translation initiation factor 2 (eIF-2 ␣ ) was enhanced ⬃ 3-fold in polR versus wild-type virus-infected L-929 cells, but neither inhibition of host gene ... See full document
11
Collybistin and gephyrin are novel components of the eukaryotic translation initiation factor 3 complex
... indeed, as a scaffold protein bridging together CB, eIF3 and mTOR, and that CB, maybe through its GEF activ- ity, is the protein responsible for activation of mTOR signaling. One possibility is that CB may promote gua- ... See full document
7
Genetic Interactions of Yeast Eukaryotic Translation Initiation Factor 5A (eIF5A) Reveal Connections to Poly(A)-Binding Protein and Protein Kinase C Signaling
... Figure 4.—Localization of wild-type eIF5A. (A) Endoge- nous eIF5A localization in fixed cells. Wild-type cells (FY23) Figure 2.—Lesions in tif51A temperature-sensitive alleles. were grown at 25⬚ to midlog phase ... See full document
13
Influenza A Virus-Induced Degradation of Eukaryotic Translation Initiation Factor 4B Contributes to Viral Replication by Suppressing IFITM3 Protein Expression
... cellular translation machinery and its role during the viral infection have come into the focus of interest ...the translation of host mRNAs, thereby suppressing host innate defenses ...of eukaryotic ... See full document
11
Revisiting an old acquaintance: role for eIF5A in diabetes
... type 2 diabe- tes and appears to result in part from the local release of proinflammatory ...identify eukaryotic translation initiation factor 5A (eIF5A) as a critical regulator of the ... See full document
5
Upregulation of a novel eukaryotic translation initiation factor 5A (eIF5A) in dengue 2 virus infected mosquito cells
... C6/36 cells (~2 × 10 6 cells/tube) were collected and infected with the Den-2 virus at an MOI of 1. After 1 h of absorption, cells were treated with 10 μ M ciclopirox olamine (CPO, Sigma) to inhibit the ... See full document
9
Aberrations in translational regulation are associated with poor prognosis in hormone receptor positive breast cancer
... protein translation by binding to the translation initiation factor eIF4A ...protein translation, inhi- biting the eukaryotic eIF4A family of RNA helicases ... See full document
11
Functional role of eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) in NSCLC
... the eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) is related to tumorigenesis and tumor progression in breast cancer ...protein translation by serving as a scaffold and ... See full document
10
Characterization of poliovirus 2A proteinase by mutational analysis: residues required for autocatalytic activity are essential for induction of cleavage of eukaryotic initiation factor 4F polypeptide p220.
... A second function of 2APro in poliovirus infection of HeLa cells is in inducing cleavage of the 220-kDa polypeptide p220 component of eukaryotic translation initiation factor eIF-4F 8, 9[r] ... See full document
6
Frequent activation of EGFR in advanced chordomas
... “ 2+ ” ), and nine other cases were considered weakly and discontinuously stained in more than 10% of the cells (scored as ...cases 2, 4, 7, 17 and 30: stronger EGFR staining was observed in the advanced in ... See full document
16
Restoring synaptic plasticity and memory in mouse models of Alzheimer’s disease by PKR inhibition
... by eukaryotic translation initiation factor 2α (eIF2α) [6, ...mRNA translation, eIF2α phos- phorylation enhances translation of the specific group of mRNAs such as β-site APP ... See full document
10
Multiple isoelectric forms of poliovirus RNA-dependent RNA polymerase: evidence for phosphorylation.
... The host cell protein required for in vitro replication of poliovirus is a protein kinase that phosphorylates eukaryotic initiation factor 2.. ATP is required for initiation of polioviru[r] ... See full document
6
Diverse roles of endoplasmic reticulum stress sensors in bacterial infection
... Bacterial infection often leads to cellular damage, primarily marked by loss of cellular integrity and cell death. However, in recent years, it is being increasingly recognized that, in individual cells, there are graded ... See full document
6
Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma
... selective translation of specific mRNAs that promote tumor survival and growth (6, ...tion initiation factors, which contribute to aberrant translational control, have been reported in a wide range of ... See full document
14
The eukaryotic translation elongation factor 1A regulation of actin stress fibers is important for infectious RSV production
... We previously demonstrated that eEF1A knock-down reduces RSV replication and subsequent shed virus [8]. Considering the role of actin in RSV trafficking and as- sembly [20] and the association between actin and eEF1A ... See full document
10
Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model
... As eukaryotic translation initiation factor 4E (eIF4E) cooper- ates with c-Myc during lymphomagenesis, induces drug resistance, and is a genetic modifier of the rapamycin response, we have ... See full document
11
Review Article Autophagy, a process within reperfusion injury: an update
... cardiac function- ing, as the turnover/regeneration is very slow; only about 1% of cardiomyocytes are renewed annually at the age of 25 which declines to ...from 2 minutes to ... See full document
20
High expression of eIF3d is associated with poor prognosis in patients with gastric cancer
... A total of 210 patients with GC who had received curative gas- trectomy in the Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China, between January 2006 and October 2010 were enrolled in ... See full document
6
Studying Hepatitis C Virus: Making the Best of a Bad Virus
... ture failed. Through the use of bioinformatics, chimpanzee infections, surrogate expression systems, and biochemical anal- ysis, the structure of the HCV genome, the polyprotein pro- cessing mechanisms, the protein ... See full document
15
Related subjects