[PDF] Top 20 Molecular Classification of Colorectal Cancer Using Gene Expression Profile of Tumor Samples
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Molecular Classification of Colorectal Cancer Using Gene Expression Profile of Tumor Samples
... Figure 4: Differential gene expression analysis of 57 genes in our CRC tumor samples compared to 232. the matched normal samples.[r] ... See full document
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The expression profile and clinical significance of circRNA0003906 in colorectal cancer
... gender, tumor diameter, T classifica- tion, TNM stage, carcinoembryonic antigen level, and car- bohydrate antigen 19-9 level (Table ...(N classification) ... See full document
7
Plasma miR-324-3p and miR-1285 as diagnostic and prognostic biomarkers for early stage lung squamous cell carcinoma
... and cancer-free controls using TLDA technology and identified the most significantly altered 20 ...lung cancer, such as Let-7, miR-21, or miR-155 [11, ...LSCC. Using a logistic regression ... See full document
12
Basal-like breast cancer: molecular profiles, clinical features and survival outcomes
... distinct expression levels between tumours and ...breast cancer are linked to genomic changes or variations from healthy to cancer- ous ...the expression levels in tumours are (a) lower than, ... See full document
17
GENT2: an updated gene expression database for normal and tumor tissues
... available gene expres- sion datasets have accumulated since GENT was first published in 2011, and the need was recognized to upgrade the GENT system both quantitatively and quali- ...more samples and newer ... See full document
8
Molecular classification of cancer with the 92-gene assay in cytology and limited tissue samples
... a molecular classifier that predicts tumor type and subtype through an algorithmic- based comparison of a tumor’s gene expression profile to a reference database of known tumor ... See full document
12
Time course analysis based on gene expression profile and identification of target molecules for colorectal cancer
... mRNA expression profile of GSE37178 was down- loaded from GEO database ...paired tumor and normal specimens collecting from 14 patients who underwent surgical resection at the INT-MI (Fon- dazione ... See full document
9
Gene Selection for Tumor Classification Using Microarray Gene Expression Data
... type. Using DNA microarray analysis thousands of individual genes can be spotted on a single square inch ...genome-wide expression data from cancerous tissues gives insight into the gene ... See full document
6
Gene expression profile predictive of response to chemotherapy in metastatic colorectal cancer
... appropriate. Tumor response was evaluated according to the standard RECIST ...performed using the Statistical Package for the Social Sciences software (SPSS ... See full document
9
Original Article Expression profile of mucin-associated sialyl-Tn antigen in Chinese patients with different colorectal lesions (adenomas, carcinomas)
... in colorectal cancer. But the associations between sTn and colorectal cancer remain elusive and ...the expression profile of sTn antigen in a series of human colorectal ... See full document
6
Gene-expression analysis of a colorectal cancer-specific discriminatory transcript set on formalin-fixed, paraffin-embedded (FFPE) tissue samples
... cancer already in premalignant lesions and in CRC [42] and it could accelerate tumor cell growth by in- ducing cell proliferation in a mouse implantation model [43]. Collagen type XII (COL12A1) was re- ... See full document
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The Transcriptional Activity of LAMP3 Gene Involved in Autophagocytosis in Colorectal Cancer LAMP3 Expression in Colorectal Cancer
... in tumor metastasis and drug ...to tumor cells proliferation, migration and ...3 expression using bioinformatic ...colon samples and colon cancer samples in four stages. ... See full document
13
Context matters-consensus molecular subtypes of colorectal cancer as biomarkers for clinical trials.
... heterogeneous gene expression ...patient samples), we suggested that the presence of TA sub-clones even in non-TA tumors is associated with anti-EGFR therapy response ...visible using the CMS ... See full document
8
<p>Molecular subtype classification of papillary renal cell cancer using miRNA expression</p>
... independent samples t-test was used to identify differentially expressed (DE) miRNAs between tumor and normal samples of ...clustering using DE miRNA expression data to analyze ... See full document
12
Molecular apocrine differentiation is a common feature of breast cancer in patients with germline PTEN mutations
... ERBB2 gene (Figure ...the molecular apocrine ...in tumor 118 include a specific loss at the chromosomal band 10q23 that spans the PTEN gene (Figure ...corresponding tumor DNA confirmed ... See full document
13
LYAR promotes colorectal cancer cell mobility by activating galectin-1 expression
... Colorectal cancer (CRC) is one of the leading causes of cancer-related death ...the molecular mechanisms of CRC pathogenesis are not fully ...cells. Gene expression ... See full document
12
TP53mutation status and gene expression profiles are powerful prognostic markers of breast cancer
... breast cancer cases were studied; 80 of these tumors were analyzed using cDNA microarrays, along with one normal breast tissue sample collected from breast reduction ...Patient samples were ... See full document
16
Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma
... IMP2 expression was not related to lymph node metastasis (data not shown), distant metastasis showed increased IMP2 protein levels compared to primary tumor tissue (Figure 3C; Table 1; p = ...IMP2 ... See full document
8
Gene expression profile analysis of colorectal cancer to investigate potential mechanisms using bioinformatics
... In summary, our study provides a comprehensive bioin- formatics analysis of DEGs which may be involved in the progression and development of CRC. The findings of this study may provide a basis for understanding the ... See full document
8
DNA methylation profile of the DKK2 gene as a biomarker in patients with colorectal cancer
... its gene products exhibit tumor-suppressive ...the expression of DKK2 in colon tumor cell lines, as well as its promoter methylation status in colon tumor cell lines and primary tumors ... See full document
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