[PDF] Top 20 Can we rely on the multiplex ligation-dependent probe amplification method (MLPA) for prenatal diagnosis?
Has 10000 "Can we rely on the multiplex ligation-dependent probe amplification method (MLPA) for prenatal diagnosis?" found on our website. Below are the top 20 most common "Can we rely on the multiplex ligation-dependent probe amplification method (MLPA) for prenatal diagnosis?".
Can we rely on the multiplex ligation-dependent probe amplification method (MLPA) for prenatal diagnosis?
... powerful method that reveals a range of numerical and structural chromosomal abnormalities with high precision ...this method time- consuming, labor-intensive, and expensive (5- ...latter can result ... See full document
6
A de novo duplication of chromosome 9q34.13-qter in a fetus with Tetralogy of Fallot Syndrome
... and prenatal diagnosis at 25 3/7 weeks of gestation due to her male fetus, diagnosed as Tetralogy of Fallot Syndrome (TOF) by prenatal ...non-invasive prenatal testing (NIPT) using low ... See full document
5
Subtelomeric multiplex ligation-dependent probe amplification as a supplement for rapid prenatal detection of fetal chromosomal aberrations
... Cryptic, unbalanced subtelomeric rearrangements have been identified as an important contributor (0.5-4.1%) to the etiology of fetal malformations [8,26,27]. In this study, 3 (0.8%) normal karyotypes were found to have ... See full document
7
Multiplex Ligation Dependent Probe Amplification in X linked Recessive Muscular Dystrophy in Korean Subjects
... genetic diagnosis of DMD/BMD is important, and the obtained genetic information may help clinicians provide appropriate and reliable genetic counseling, prenatal diagno- sis, and gene therapy for those at ... See full document
6
Multiplex ligation dependent probe amplification (MLPA) for rapid distinction between unique sequence positive and negative marker chromosomes in prenatal diagnosis
... the MLPA technique for characterisation of some speci- fic sSMC has already been described in postnatal cyto- genetics ...paper, we show that MLPA with centromere and telomere kits may be a quick ... See full document
10
SLC26A4 gene copy number variations in Chinese patients with non syndromic enlarged vestibular aqueduct
... Multiplex ligation-dependent probe amplification (MLPA) was used to screen for CNVs of the SLC26A4 gene in the present ...study. MLPA is a novel semi-quantitative ... See full document
6
Multiplex ligation dependent probe amplification versus karyotyping in prenatal diagnosis: the M A K E study
... Women undergoing amniocentesis for ultrasound abnor- malities, parental chromosomal abnormality, or a previ- ous child with chromosomal abnormality are excluded. Procedures, recruitment and collection of baseline data ... See full document
5
Multiplex ligation-dependent probe amplification and array comparative genomic hybridization analyses for prenatal diagnosis of cytogenomic abnormalities
... of prenatal aneuploidy but these methods were limited to a few chromosomal loci ...[5-7]. MLPA using aneuploidy probe mix (P095), subtelomeric probe mixes (P036 and P070) and microdeletion ... See full document
10
A simple way to evaluate self designed probes for tumor specific Multiplex Ligation dependent Probe Amplification (MLPA)
... Three MLPA self-designed target probes were included in a MLPA study to validate the CNV calculation ...breast can- cer samples (manuscript in ...the probe regions, were analyzed. MLPA ... See full document
6
Analysis of chromosome 22q11 copy number variations by multiplex ligation-dependent probe amplification for prenatal diagnosis of congenital heart defect
... for detail diagnosis. In total, 225 fetuses presenting with CHD were enrolled in the study. The distribution of different clinical manifestations was shown in Table 1. The CHD cases included in the study were: ... See full document
7
Evaluation of multiplex ligation dependent probe amplification (MLPA) for identification of acute lymphoblastic leukemia with an intrachromosomal amplification of chromosome 21 (iAMP21) in a Brazilian population
... The method nowadays internationally recommended to identify an iAMP21 is fluorescence in situ hybridization (FISH) using probes directed to the Runt Related Transcription Factor 1 (RUNX1 ) gene, present by three ... See full document
10
Altered Methylation at MicroRNA-Associated CpG Islands in Hereditary and Sporadic Carcinomas: A Methylation-Specific Multiplex Ligation-Dependent Probe Amplification (MS-MLPA)-Based Approach
... the diagnosis, prognosis and treatment of ...understood. We investigated 96 colorectal carcinomas, 58 gastric carcinomas and 41 endometrial car- cinomas, occurring as part of inherited DNA mismatch repair ... See full document
10
Identification of Salmonella enterica Serovar Typhi Genotypes by Use of Rapid Multiplex Ligation Dependent Probe Amplification
... methodologies can be used to improve bac- terial subtyping (10, 25, ...endemic. We aimed to address this and devel- oped a simple and reproducible ...subtyping method that can be performed in ... See full document
9
Molecular identification of Clonorchis sinensis and discrimination with other opisthorchid liver fluke species using multiple Ligation depended Probe Amplification (MLPA)
... study we evaluate a PCR-based molecular identification method, Multiplex Ligation-dependent Probe Amplification (MLPA), which allows rapid and specific detection of ... See full document
12
Clinical experience with multiplex ligation-dependent probe amplification for microdeletion syndromes in prenatal diagnosis: 7522 pregnant Korean women
... for prenatal diagnosis, even when cases with ultrasonographic evidence for fetal abnormalities are ...study, we present our experience of using the MLPA P245 assay during invasive ... See full document
6
Original Article Screening of the copy number increase of AKT in lung carcinoma by custom-designed MLPA
... for probe design” by MRC-Holland (Amsterdam, the Netherlands) (Table ...Each probe consists of two components: sequences complementary to the 5’ or 3’ target sequence, predominantly in exons, and a ... See full document
13
Three Isothermal Amplification Techniques for Rapid Identification of Cladophialophora carrionii, an Agent of Human Chromoblastomycosis
... mol MLPA probe mix (MLPA-1AW and MLPA-1FW), and 1 l 10 ⫻ ampligase DNA ligase RxN ...buffer. Probe ligation was conducted with one cycle of denatur- ation for 5 min at 95°C, ... See full document
5
Application of Multiplex Ligation-Dependent Probe Amplification in Determining the Copy Number Alterations of HER Gene Family Members in Invasive Ductal Breast Carcinoma
... family can be aberrantly activated by genomic mutations such as genomic copy number gain and as a result, immanent tumorigenic processes, can appear as pathogenesis cause of BC ...ERBB2 amplification ... See full document
11
Comprehensive chronic lymphocytic leukemia diagnostics by combined multiplex ligation dependent probe amplification (MLPA) and interphase fluorescence in situ hybridization (iFISH)
... by MLPA (~58%) and 100 (~61%) by routine iFISH. MLPA was not able to distinguish reliably between mono- and biallelic ...to MLPA in samples with low tumor cell load. On the other hand MLPA ... See full document
9
Development of new technological applications for post- and prenatal diagnosis of the hemoglobinopathies
... a few more less frequent variants causes the severe SCD. The valine for glutamic acid replacement results in hemoglobin tetramers that, when deoxygenated, can aggregate into polymers rather than remaining soluble. ... See full document
204
Related subjects