[PDF] Top 20 At new heights – endodermal lineages in development and disease

... of endodermal cells uncovered an anteroposterior flux of cells leading to posterior compaction and folding of the caudal intestinal ...directs endodermal progenitors to the posterior and is controlled by a ... See full document

... on development. This effect has serious implications for human disease, since, unlike many disease genes, loss of heterozygosity is not required for phenotypic ... See full document

... During development many thousands of genes are expressed to control patterning of the developing ...of development, very rapid cell proliferation and differentiation occurs, but this rapid growth is under ... See full document

... brain development awaits more in-depth studies, investigations using animal models have revealed a number of possible functions in neurogenesis, neuronal migration and differentiation, and axis ... See full document

... Int I Dc, BioI 35 2St) 295 (I t)t)1) 289 Human brain gangliosides in development, aging and disease IVICA KRACUN'*, HARALD ROSNER', VALERIJA DRNOVSEK', MARIJA HEFFER LAUC', CEDOMIR COSOVIC' and GORDAN[.] ... See full document

... meningococcal disease incidence in Europe since 1999, decreasing from ...B disease incidence, which may be attribut- able to natural ...With new protein-based substitute serogroup B vaccines such as ... See full document

... Fig. 1. Snail and the Epithelial-Mesenchymal Transition (EMT) in health and disease. (A,B) The EMT is fundamental for the development of many tissues and organs, including the neural crest and the mesoderm ... See full document

... During gastrulation, cardiovascular progenitors are among the first mesodermal cells to emerge from the primitive streak between E6.5 and E7.5 in the mouse embryo. Lineage tracing experiments have shown that ... See full document

... gland dysfunction has been increasingly implicated as having a significant role in the breakdown of the healthy tear complex. Meibum secretion serves to preserve healthy tear film. Meibomian gland dysfunction causes the ... See full document

... Germline or early embryonic alterations in IGF2 imprinting could lead to LOI in many cells of the developing organism (Dean et al., 1998). This seems to be the case in the fetal overgrowth syndrome, Beckwith-Wiedemann ... See full document

... As there were numerous recommended immunosuppres- sant regimens with various doses initiated after RT surgery, it was impossible for us to discuss the influence of each combina- tion of immunosuppressants on lithogenesis ... See full document

... In summary, we have purified human lung progenitors derived from iPSCs, and these cells are reminiscent of early stages of lung developmental differentiation. Our profiling of these cells as well as their precursors and ... See full document

... lung development is our understanding of the potency and heterogeneity of early lung mesodermal progenitors, in particular their capacity to generate the various smooth muscle and endothelial lineages in ... See full document

... M.S. Jaakkol(2002) : The potential role of environmental tobacco smoke exposure as a prognostic factor determining the development of a pre-existing respiratory or ischaemic heart disease is an important ... See full document

... Lesions in the epithelially expressed human gene FRAS1 cause Fraser syndrome, a complex disease with variable symptoms, including facial deformities and conductive hearing loss. The developmental basis of facial ... See full document

... The Mechanical Turk workers then selected a sin- gle connector word from the list and wrote a sen- tence to describe the relationship between the an- chor words and the connector word. Mechanical Turk workers were ... See full document

... presented provocative new data. He proposed that not only the neural ectoderm (as is believed) but also the non-neural ectoderm undergo epithelial to mesenchymal transitions (EMT) in the embryonic head to give ... See full document

... years of the study period (1999 to 2002). Exceptions occurred in major clusters of the following serotypes or serogroups in which isolates were not recovered in the year(s) indicated in parentheses: 5 (2000), 8 (2002), ... See full document

... Pubertal development is controlled by the hypothalamic – pituitary – gonadal axis (HPG ...the development of the HPG axis and its reawakening at ...pubertal development by increasing sex-hormone ... See full document

... down, perceived a hole near the bottom still full of snail- shells and pebbles, which we were fond of storing there with more perishable things; and, as fresh as reality, it appeared that I beheld my early playmate ... See full document