[PDF] Top 20 The non-coding landscape of head and neck squamous cell carcinoma

... HNSCC cell lines UMSCC-10B and HN-30 (Figure ...lnc-JPH1-7-knockdown cell lines, with many cells exhibiting pan-nuclear γ-H2AX staining, a defining characteristic of the apoptotic γ-H2AX response (Figure ... See full document

... and neck squamous cell carcinoma (HNSCC), the sixth leading cancer worldwide, is an aggressive can- cer form with high metastasis and recurrence rates [15, ...cancer cell invasion and ... See full document

... The Head and Neck Squamous Cell Carcinoma (HNSCC) is the sixth most common human cancer, causing 350,000 individuals die worldwide each ...small non-coding RNAs (sncRNAs) ... See full document

... and neck squamous cell carcinoma (HNSCC), including cancers of the lip, oral cavity, larynx, and pharynx, represents the seventh most common malignancy worldwide, with >650 000 cases ... See full document

... suggests that AS is implicated in the carcinogenesis and progression of cancers [4, 5]. Furthermore, research- ers have found the clinical significance of AS, and it may serve as a prognostic predictor [6]. For instance, ... See full document

... proliferation, squamous epithelial differentiation, cell survival, and invasion/metastasis, with many of the genes impacting more than a single pathway (Figure ... See full document

... and cell lines suggesting their contribution to metastasis in HNSCC through lam- inin γ2 (LAMC2) and α6 integrin ...HNSCC cell lines decreases cell migration, suggesting the role of miR-99 family as ... See full document

... on day 15, mice in the BBM group were euthanized due to the same reason. Radiation treatment continued to 23 days before suspension while combinational treatment lasted for 27 days, which was the longest treatment among ... See full document

... advanced head and neck squamous carcinoma cell (HNSCC) is dismal (<25%), and these statistics have remained largely unchanged for decades despite advances in surgical technique and ... See full document

... firmed that, in a mice model, distinct subsets of Treg cells have similar variations in function as in humans. Furthermore, CCR4 expression on the 3 subsets of mouse Tregs was investigated, finding that CCR4 was ... See full document

... The field cancerization theory suggests that there are numer- ous malignant and premalignant fields present in the mucosa of HNSCC patients (54). This can lead to a high degree of intertu- mor genetic heterogeneity in ... See full document

... cancer, head and neck squamous cell carcinoma, esophageal squamous cell carcinoma, oral squamous cell carcinoma, gallbladder cancer, pancreatic ... See full document

... with head and neck squamous cell carcinoma showed that the response to treatment , survival rate and other related outcomes were better in HPV positive types versus HPV negative ... See full document

... in head and neck squamous cell carcinoma (HNSCC); however, whether it plays a role in determining clinical outcome remains still ...reduced cell proliferation and enhanced ... See full document

... In our study, we detected the amplification of hTERC by FISH in all cases of invasive carcinoma of larynx. This result indicates demonstrated that amplification of the hTERC gene is one of the most frequent ... See full document

... prostate, non-small cell lung cancer, and head and neck squamous cell ...different cell types displaying a range of amplitudes in clock gene rhythms, with keratinocyte and ... See full document

... [4]. Squamous cell carcinoma (SCC) is the most frequent histotype among the head and neck ...of head and neck squamous cell carcinoma (HNSCC) has been ... See full document

... including head and neck cancer which suggested that blocking of this protein can prevent the ...including cell proliferation, apoptosis and ...in cell lines with combination of EGFR, TKI and ... See full document

... CD44, CD80, CD105 (ENDOGLIN): In oral SCC’s, expression of CD80 may serve as a marker for increased tumourogenicity, during early development and expression of CD44 correlated with decreased survival rate [1,8,17]. ... See full document

... or prior radiotherapy to the head and neck area were ex- cluded. All patients presented with primary disease located in the oral cavity, including mobile tongue, floor of the mouth, buccal mucosa, gingiva ... See full document