[PDF] Top 20 Noncoding RNAs in prostate cancer: the long and the short of it

... with prostate cancer. A small RNA-Seq study on 14 Chinese prostate tumors and adjacent benign tissues identified 137 lncRNAs that were significantly altered ...tate cancer. ANRIL is an ... See full document

... and short reads, and ...3684 long intergenic noncoding RNAs (lincRNAs), 733 antisense lncRNAs (anti-lncRNA) and 5 lncRNAs transcripted from intronic regions (in-lncRNA) (Table  ... See full document

... of phosphorylated splicing-associated serine arginine (SR) proteins. And it is also overexpressed in other cancers includ- ing bladder carcinoma, breast cancer, prostate cancer, and ovarian ... See full document

... Abundant short transcripts (ranging from 20 to 2500 nt) have been found to be produced from the vicinity of transcription start sites in both sense and antisense direc- tions, corresponding to peaks of Pol II ... See full document

... Multiple studies have previously been carried out examining specific genetic abnormalities as causative factors for the development of chronic diabetic complications. However, such studies have never been able to provide ... See full document

... as long non coding RNA ...of noncoding RNAs including lncRNAs have been functionally implicated in a wide variety of cellular processes [22–25] and their aberrant expression has been shown to be one ... See full document

... Noncoding RNAs (ncRNAs) are a superclass of endogenous, non-protein-coding RNA transcripts, many of which have essential functions in various cellular ...a short ncRNA (siRNA, miRNA, piRNA) and those ... See full document

... in prostate cancer cells induces tumor angiogenesis through targeting phosphatase and tensin homolog deleted on chromosome 10 (PTEN), activating AKT and ERK1/2 pathways, and upregulating HIF-1α and VEGF ... See full document

... Several studies have also demonstrated the prognostic signi fi cance of single lncRNAs in DLBCL. The lncRNA HOX transcript antisense RNA (HOTAIR) has been widely con fi rmed as a crucial regulator in human cancers. 33 ... See full document

... enhancer RNAs based on the phenomena that RNA polymerase II located to approximately 3000 activated enhancers and that RNAs could be produced from the extragenic enhancer regions of protein-coding genes ... See full document

... Pancreatic cancer (PC) is one of the leading causes of cancer-related deaths ...understood. Long noncoding RNAs (lncRNAs) provide biological functional diversity and complexity in ... See full document

... in prostate cancer [45, ...gastric cancer progression by trap- ping MTA2 in the cytosol ...colorectal cancer, osteosarcoma, hepatocellular cancer, bladder cancer and gastric ... See full document

... casc15, cancer susceptibility 15; ccaT2, colon cancer associated transcript 2; eMT, epithelial–mesenchymal transition; gaPlinc, gastric adenocarcinoma associated, positive cD44 regulator, long ... See full document

... system cancer, is highly malignant and has a poor disease ...“noncoding RNAs” (ncRNAs) are a group of RNAs that do not code for proteins, and they are categorized as structural RNAs and ... See full document

... of cancer and their ex- pression levels di ff er during the di ff erent stages, so could be of value to distinguish among patients with cancer in a very early stage (still not detectable using imaging ... See full document

... Against Cancer; AJCC: American Joint Committee on Cancer; lncRNAs: long noncoding RNAs; UCA1: urothelial carcinoma associated 1; MALAT1: metastasis-associated lung adenocarcinoma ... See full document

... about long noncoding RNAs (lncRNAs) and some related lncRNAs as molecular biomarkers or therapy strategies in human cancer and cardiovascular ...DNAs, RNAs, and ...human cancer ... See full document

... F. Long noncod- ing RNA HNF1A-AS1 indicates a poor prognosis of colorectal cancer and promotes carcinogenesis via activation of the Wnt/ β -catenin signaling ...BCAT1 long non-coding RNA acts as a ... See full document

... on long noncoding RNAs (lncRNAs), which can act as competing endogenous RNA (ceRNA) to compete for shared microRNAs (miRNAs) in the tumorigenesis of human ...The Cancer Genome ... See full document

... The NF-kB family includes transcription factors that are involved in the initiation and progression of various cancers. It has been shown that activation of the NF-kB signaling was significantly induced in cancerous cell ... See full document