[PDF] Top 20 Original Article Function and mechanism of long non-coding RNA KIAA0495 in glioma
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Original Article Function and mechanism of long non-coding RNA KIAA0495 in glioma
... carrying KIAA0495 gene sequence was used as the over-expressed KIAA0495 group (KIAA0495 ...of KIAA0495 group as the over- expression KIAA-0495 and interference of CTNNBIP1 group (K-OE+C-KD ... See full document
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Original Article Long non-coding RNA P4713 contributes to the malignant phenotypes of oral squamous cell carcinoma by activating the JAK/STAT3 pathway
... cules can localize to the nucleus, cytoplasm, or both [10]. In addition, they can function as either oncogenes or tumor suppressors [11]. Moreover, recent studies have reported that many lncRNAs are dysregulated ... See full document
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Original Article Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer
... cers [7-9]. Previous studies have proved that upregulated lncRNAs ANRIL [10], AK001796 [11], BCYRN1 [12] and HNF1A-AS1 [13] are proved to induce cell migration and tumor metastasis of NSCLC. In contrast, an lncRNA named ... See full document
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Original Article Long non-coding RNA taurine-upregulated gene 1 promotes cells proliferation, migration and invasion while represses apoptosis, and upregulates AURKA expression in hepatocellular carcinoma
... malignancy, recurrence and metastasis [4, 5]. According to the biological characteristics of malignant tumor, aberrant cell activities via regulating multiple genes, molecules as well as signal pathways, contribute to ... See full document
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Original Article High expression of long non-coding RNA MALAT1 correlates with raised acute respiratory distress syndrome risk, disease severity, and increased mortality in sepstic patients
... organize RNA-protein complex with protein and affect mRNA cleav- age; (3) manage protein activity via binding to proteins; (4) regulate epigenetic changes; (5) change the cellular localization of functional ... See full document
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Original Article Up-regulated expression of long non-coding RNA ZFAS1 associates with aggressive tumor progression and poor prognosis in gastric cancer patients
... could function as an oncogene in hepatocellular carcinoma progres- sion by binding miR-150 and abrogating its tumor suppressive function in this setting ... See full document
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Original Article MALAT1 is an oncogenic long non-coding RNA associated with tumor invasion in non-small cell lung cancer regulated by DNA methylation
... stage non-small cell lung cancer and passive immunization of NSCLC tumor-bearing mice with neutralizing anti- CXCL5 antibodies resulted in reduced tumor growth, tumor vascularity and metastases [34, ...the ... See full document
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Original Article Long non-coding RNA BANCR promotes pancreatic ductal adenocarcinoma cell growth and metastasis via affecting epithelial-mesenchymal transition
... Background: Long non-coding RNAs (lncRNA) have been shown to play critical roles in the development and progression of ...tissues. RNA interference (RNAi) was used to investigate the ... See full document
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Original Article Long non coding RNA CCND2-AS1 promotes gastric cancer growth through Akt signaling
... LncRNA CCND2-AS1 involved in proliferation and invasion of cancers. For example, CCND2- AS1 upregulated in glioma and promoted glio- ma proliferation through affecting Wnt/β-ca- tenin signaling [18]. In present ... See full document
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Original Article Differential long non-coding RNA (lncRNA) profiles associated with hippocampal sclerosis in human mesial temporal lobe epilepsy
... and function of lncRNAs in human MTLE with HS are still ...The coding and non-coding gene co-expression net- work, gene ontology and pathway analyses, and cis-/trans-acting lncRNA prediction ... See full document
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Original Article Long non-coding RNA HOST2 predicts poor prognosis and promotes cell proliferation and invasion in non-small cell lung cancer
... ing to the regulation of proteoglycan link protein (LP) that can specifically regulate the formation of extracellular matrix [28]. Under the regula- tion of LP, the intercellular coupling is enhanced and benefits for ... See full document
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Original Article Long non-coding RNA SNHG1 is an unfavorable prognostic factor and promotes cell proliferation and migration by Wnt/β-catenin pathway in epithelial ovarian cancer
... In summary, this study provides the first link between SNHG1 expression and EOC develop- ment. We found that SNHG1 was overex- pressed in EOC tissues and its upregulation may be correlated with unfavorable prognosis of ... See full document
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Original Article Association of long non-coding RNA HOTTIP with progression and prognosis in colorectal cancer
... HOTTIP is located at the 5’ tip of the HOXA locus and coordinates the activation of multiple 5’ HOXA genes [14]. In one previous study, Li and colleagues observed that HOTTIP was one of the most significantly upregulated ... See full document
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<p>Long Non-Coding RNA PART1 Exerts Tumor Suppressive Functions in Glioma via Sponging miR-190a-3p and Inactivation of PTEN/AKT Pathway</p>
... Long non-coding RNAs (lncRNAs) are single-stranded RNA longer than 200 nucleotides with no protein coding ...protein function, lncRNAs are essential for numer- ous normal ... See full document
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Original Article Overexpression of long non-coding RNA loc285194 suppresses cell proliferation and migration in hepatocellular carcinoma
... 3]. RNA molecules without protein-coding function are such kind of “dark matters” and collectively named as non-coding RNAs (ncRNAs) ...[4]. Long non-coding ... See full document
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Original Article Long non-coding RNA ANRIL overexpression predicts poor prognosis and promotes metastasis and proliferation in perihilar cholangiocarcinoma
... Abstract: Perihilar cholangiocarcinoma (PHCC) is still a great challenge for doctors because of its aggressive feature and poor survival rate. The molecular mechanisms of PHCC initiation and progression remain obscure at ... See full document
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Original Article Long non-coding RNA expression profile in atrial fibrillation
... recently, long non-coding RNAs (lncRNAs), generally defined as non-coding RNAs of more than 200 nt in length without known protein- coding function [15], have risen to ... See full document
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Original Article The expressions and clinical implications of long intragenic non-coding RNA-p21 and glucose transporter 1 in primary hepatocellular carcinoma
... molecular mechanism (81560460/H1602) and the Self-Raised Sci- entific Research Fund of the Ministry of Health in Guangxi Zhuang Autonomous Region for Effects of parenteral and enteral immune nutri- tion on ... See full document
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Original Article Increased expression of long non-coding RNA HOXC-AS1 associates with the malignant status and poor prognosis in glioma
... high-grade glioma tissues compared with that in low-grade glioma and normal brain tissues, suggesting that it might play an important role in the development of ...in glioma was negatively correlated ... See full document
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Original Article Prognosis and clinicopathology of long non-coding RNA HOTTIP in tumors
... script, lncRNA HOTTIP, which was recently revealed [8]. As a tumor promotor, HOTTIP is upregulated in a number of tumors [10-17]. As for the precise mechanism of the regulation of HOTTIP in carcinogenesis, it is ... See full document
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