[PDF] Top 20 Original Article Identification of the potential targets of miR-143-3p in colorectal cancer through bioinformatics analysis
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Original Article Identification of the potential targets of miR-143-3p in colorectal cancer through bioinformatics analysis
... prospective targets based on bioinformatics in our study (MAPK1, PTPN23, ERBB3, PKN2, KLF5, YARS, ETV6, PDPR and YWHAB), we found that KLF5 has been report- ed to be a target of ... See full document
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Original Article miR-455-3p functions as a tumor suppressor in colorectal cancer and inhibits cell proliferation by targeting TPT1
... of miR- 455-3p using ...with miR-455-3p mimic or miR-con and wt or mut 3’-UTR TPT1 ...that miR-455-3p significantly reduced the lucifer- ase activity of the wt 3’-UTR TPT1 ... See full document
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Original Article The potential value of miR-1 and miR-374b as biomarkers for colorectal cancer
... of colorectal cancer (CRC) is growing due to the unsatisfactory specificity and sensitivity of the existing screening ...following: miR-1, -145, -145*, -137, -363, -143, -4770, -490-5p, -9, ... See full document
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Original Article miR-338-3p suppresses colorectal cancer proliferation and progression by inhibiting MACC1
... that miR-338-3p UACGACC could completely bind AUGCUGG (position 1932-1938) of MACC1 mRNA 3’UTR using TargetScan, PicTar, and miRanda ...PCR analysis (Figure ...1E). miR-338-3p low ... See full document
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Original Article miR-143 inhibits migration and invasion through regulating LASP1 in human esophageal cancer
... Bioinformatic analysis using Targetscan data- base revealed LASP1 as a potential target gene of ...and miR-NC mimics or miR-143 were transfect- ed into HEK293T cells by Lipofectamine ... See full document
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Original Article Identification of the clinical diagnostic value of miR-10b-5p and the key targets and pathways in glioma, a study based on meta-analysis and bioinformatics
... between miR-10b-5p and glioma remains ...of miR-10b-5p in glioma and to un- cover the potential molecular regulatory mechanisms of miR-10b-5p in ...ta-analysis through searching ... See full document
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Original Article Identification of potential biomarkers in pathogenesis and liver metastasis of colorectal cancer: a bioinformatics study
... liver metastasis [15]. In this study, reanalysis of published microarray about the incidence and metastasis of CRC, several potential the- rapeutic targets were identified. MEIS1 is one of the biomarkers we ... See full document
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Original Article MiR-452-5p may serve as an oncogene in colorectal cancer through targeting CDKN1B: a study based on bioinformatics analysis and dual-luciferase reporter assay
... 1156 potential target genes sug- gested that these genes were significantly assembled in 151, 46 and 50 terms of BP, CC and MF, respectively (all ...1156 potential tar- get genes may be involved in 37 ... See full document
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Original Article Down-regulation of miR-133a-3p in hepatocellular carcinoma tissues and its potential regulatory molecular mechanism: a study of qRT-PCR and bioinformatics analysis
... and potential molec- ular mechanisms of miR-133a-3p in ...sion, miR-133a-3p could be assessed as a probable candidate for molecular biomarker for HCC in clinic; even this finding needs ... See full document
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Original Article Potential targets and clinical value of miR-490-5p in hepatocellular carcinoma: a study based on TCGA, qRT-PCR and bioinformatics analyses
... explore potential targets and clinical value of miR-490-5p in the oncogenesis and progres- sion of hepatocellular carcinoma ...of miR-490-5p was accessed through The Cancer ... See full document
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Original Article Prospective target genes and pathways of miR-30a-5p in colorectal cancer: an investigation using TCGA and bioinformatics analysis
... the potential mechanism of this action remains largely ...growth through aerobic glycolysis was strongly sup- ported by Billiard et al, who demonstrated that inhibiting LDHA with the inhibitor quinoline ... See full document
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Original Article Identification of potential biomarkers for risk analysis of colorectal cancer using a combined bioinformatics analysis
... sis through somatostatin receptor signaling, and thus involved in the CRC tumorigenesis [18, ...colon cancer cells and mutation of GRM8 was related to human cancers ... See full document
7
Original Article Genetic alteration and prospective signaling pathways of miR-517a-3p in bladder cancer: a study based on miRNA sequencing data and bioinformatics methods
... bladder cancer (BC). Methods: The clinical importance of miR-517a-3p expression and genetic altera- tion in BC was unraveled by using The Cancer Genome Atlas (TCGA), cBioPortal, Gene ... See full document
15
Original Article Effect of miR-143 on the apoptosis of osteosarcoma cells
... To further elucidate the bio- logical role of miR-143 in osteosarcoma occurrence, it is necessary to find its tar- get gene. Based on soft- ware estimation, Bcl-2 may be the candidate. As one anti-apoptotic ... See full document
6
Original Article miR-145 and miR-143 expression differ between Uygur and Han women with endometrial cancer
... of miR-145/143 expression in Uygur and Han women with endometrial cancer in Xinjiang and assess their effects and ethnic factor in the occur- rence of endometrial ...cancer. miR-145 and ... See full document
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Identification of novel biomarkers affecting the metastasis of colorectal cancer through bioinformatics analysis and validation through qRT-PCR
... : Colorectal cancer; RNA-Seq: RNA-sequencing; TCGA : The Cancer Genome Atlas; WGCNA: Weighted gene co-expression network analysis; DEGs: Dif- ferentially expressed genes; DELs: Differentially ... See full document
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Original Article MicroRNA-140-3p expression level is an independent prognostic factor in NSCLC
... of miR-140-3p in 224 pairs of human lung cancer tissues and normal tissues were analyzed using ...and miR-140-3p was analyzed by chi-square ...of miR-140-3p in NSCLC ... See full document
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Original Article MiR-489-3p inhibits cervical cancer cell migration and invasion through regulating Wnt/β-catenin signaling pathways
... lung cancer cells [1]. However, role of miR-489- 3p in cervical cancer has not been ...of miR-489-3p in cervical ...of miR-489-3p in cervical can- cer tissues and ... See full document
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Original Article miR-539-3P inhibits proliferation and invasion of gastric cancer cells by targeting CTBP1
... reported miR-539 functions as a tumor suppressor in various cancers including breast cancer [17], lung cancer [18], colorectal cancer [19], hepatocellular carcinoma [20] and ... See full document
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Original Article MiR-296 promotes colorectal cancer cells growth through regulating NF-κB
... that miR-296 overexpression promoted colorectal cancer cell ...whether miR-296 was related to the speed of apoptosis induction in the future ...that miR-296 expression was suppressed in ... See full document
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