[PDF] Top 20 Original Article miR-143 inhibits osteosarcoma cell proliferation by down-regulating K-ras expression
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Original Article miR-143 inhibits osteosarcoma cell proliferation by down-regulating K-ras expression
... Abstract: Osteosarcoma is a primary bone malignancy, and it usually occurs in children and adolescents under 20 years ...old. Osteosarcoma is highly malignant, and the tumor cells will migrate to brain, ... See full document
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Original Article Down-regulation of miR-34a promotes the cell proliferation and inhibits apoptosis in glaucoma
... of miR-34a in glaucoma ...of miR-34a expression on HTM and GTM cell proliferation and apoptosis and to explore the possible ...mRNA expression of miR-34a in HTM and GTM ... See full document
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MicroRNA-524 promotes cell proliferation by down-regulating PTEN expression in osteosarcoma
... or inhibits translation of target miRNAs through complete or incomplete comple- mentary binding to the 3 ′ -UTR of target mRNA, thereby regulating expression of target genes and affecting cell ... See full document
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Original Article Diphenyl difluoroketone inhibits energy metabolism and biological behavior of lung cancer cells by down-regulating glucose transporter 1 expression
... non-small cell lung cancer cells accompanied by increasing glucose metabo- lism ...and cell types, although frequently at low levels and in conjunction with more tissue-restricted glucose transporter ... See full document
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Original Article Down-regulation of SERPINA3 by miR-613 inhibits melanoma cell proliferation and invasion
... the expression level of target genes by sequence-specific inter- actions with the 3’-UTR of cognate mRNAs ...individual miR is capable of suppressing many kinds of mRNAs, they func- tion as elementary ... See full document
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Original Article MiR-199a inhibits the ability of proliferation and migration by regulating CD44-Ezrin signaling in cutaneous squamous cell carcinoma cells
... ed expression of miRNA-199a was observed in liver, breast, and bladder cancer ...the expression of miRNA- 199a was capability of decreasing the prolifera- tion of gastric cancer cells by targeting the mTOR ... See full document
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Original Article Low-expression of miR-7 promotes cell proliferation and exhibits prognostic value in osteosarcoma patients
... that miR-7 was down-regulated in glioblastoma, the differenc- es were that miR-7 decreased viability and invasiveness of primary glioblastoma lines in Kefas et al’ study while it inhibits ... See full document
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Original Article Effect of miR-143 on proliferation of osteosarcoma cells under low dosage cisplatin
... and osteosarcoma as either tumor activa- tor or inhibitor ...miRNA expression in tumors. This study thus focused on the osteosarcoma-specific miRNAs un- der the exposure of lower dosage of ... See full document
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Original Article MiRNA-15a inhibits proliferation, migration and invasion by targeting TNFAIP1 in human osteosarcoma cells
... of osteosarcoma have been studied for a long ...in regulating tumor ...gene expression by the inhibition of the translation and/or decreasing of the stability of target mRNAs ... See full document
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Original Article miR-451 inhibits invasion and proliferation of bladder cancer by regulating EMT
... showed cell morphology changed from the initial compact polygons into loose spindle, especially 5637 cell line (Figure ...by miR-451 in the EMT process, we investigated the expression of four ... See full document
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Original Article microRNA-204 inhibits cell proliferation in T-cell acute lymphoblastic leukemia by down-regulating SOX4
... found miR-204 was significant- ly decreased in T-leukemic cells compared to the T-cell ...pic expression of miR-204 could inhibit cell pro- liferation, migration and invasion of T-ALL ... See full document
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Original Article miR-143 inhibits migration and invasion through regulating LASP1 in human esophageal cancer
... LASP1 expression was significantly lower com- pared to those with low LASP1 expression (Figure ...that miR-143 expression significantly correlat- ed with that of LASP1 (Figure ...of ... See full document
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Original Article miR-374a promotes the proliferation of osteosarcoma cell proliferation by targeting Axin2
... the mir-Vana miRNA Isolation Kit (Ambion) according to the manufacturer’s pro- ...the cell lines were extract- ed using Trizol reagent (Invitrogen) according to the manufacturer’s ...of miR- 374a and ... See full document
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Original Article Down-regulation of miR-92a inhibits cell proliferation and invasion but induces apoptosis of gastric cancer by regulating FBXW7
... and miR-92a has been demonstrated to play significant roles in the development, metastasis and diagnosis of lots of tumors [16, ...Recently, miR-92a has been reported functions as a biomarker in the detec- ... See full document
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Original Article MiR-29a is down-regulated and inhibits cell proliferation in osteosarcoma: a meta analysis
... MAS system provided by CapitalBio company (Molecule Annotation System, http://bioinfo. capitalbio.com/mas3/) was used to analyze the biological roles of differentially expressed mRNAs. Gene functions were classified into ... See full document
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Original Article miR-143 down-regulates TLR2 expression in hepatoma cells and inhibits hepatoma cell proliferation and invasion
... HepG2 cell line was provided and stored by the Experimental Center for Biome- dical Research, Xi’an Jiaotong University Scho- ol of Medicine; fetal bovine serum (Evergreen) was purchased from Zhejiang Tianhang ... See full document
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Original Article MiR-211 inhibits cell proliferation and invasion of gastric cancer by down-regulating SOX4
... Total RNA was extracted from tissues or cells using Trizol reagent (Invitrogen, USA) and then both miRNA and mRNA were reverse tran- scribed to cDNA. The reverse transcription was performed by using reverse transcription ... See full document
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Original Article MiR-218 suppresses osteosarcoma proliferation by down-regulating BMI1
... with osteosarcoma are still very high, but early detection and timely treatment has increased the survival ...gene expression by complementary base pairing to specific mRNAs and play important roles in a ... See full document
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Original Article Curcumin inhibits the proliferation and invasion of human osteosarcoma cell line MG-63 by regulating miR-138
... of cell cycle, studies showed that it was the adverse prognostic factor of diffuse large B-cell lymphoma (DLBCL) ...the expression levels of Smad4, NFκB p65 and cyclin D3 with western blotting method ... See full document
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Original Article Effect of miR-143 on the apoptosis of osteosarcoma cells
... of osteosarcoma has been remarkably improved, but still leaving the tumor metastasis and/or re-occurrence as major reasons causing tumor related mortality Exosome-formed synthetic microRNA-143 is ... See full document
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