[PDF] Top 20 Original Article Mechanism of bladder dysfunction in the diabetic rat
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Original Article Mechanism of bladder dysfunction in the diabetic rat
... each rat. The total protein extracted from the bladder tissues was subjected to 4% SDS-PAGE gel electropho- resis, membrane-transfer, one-hour blocking with TBST buffer containing 5% skim milk pow- ... See full document
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Original Article Poly(ADP-ribose) polymerase inhibition restores bladder function by suppressing bladder apoptosis in diabetic rats
... Although diabetic cystopathy has a higher prevalence in patients with diabetes mellitus, its mechanism is still unclear and there is no effective therapeutic ...stress-induced bladder apoptosis, ... See full document
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MECHANISMS OF UROLOGIC COMPLICATIONS IN STREPTOZOTOCIN INDUCED TYPE 1 DIABETES MELLITUS
... urinary bladder located and excised rapidly and placed in organ ...urinary bladder detrusor muscles were blotted, weighed and dissolved in concentrated nitric acid for the measurements of cation ...The ... See full document
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Original Article Involvement of RhoA/ROCK1 signaling pathway in hyperglycemia-induced microvascular endothelial dysfunction in diabetic retinopathy
... RhoA, are molecular switches that respond to cell surface receptors for various cytokines, growth factors, adhesion molecules, and G-protein-coupled receptors by cycling between an inactive guanosine diphosphate (GDP)- ... See full document
10
Original Article Anti-inflammatory effects of lycopene prevents cardiac dysfunction in streptozotocin-diabetic rats
... in diabetic patients, which results in heart failure and high ...ventricular dysfunction is an early sign of dia- betic ...of diabetic cardiomyopathy [8, ... See full document
8
Original Article Neuroprotective effects of lidocaine on early postoperative cognitive dysfunction and the possible mechanism
... cognitive dysfunction (POCD) is induced by general anesthesia and ...possible mechanism was ...possible mechanism was associated with decreased cerebral oxygen and anaerobic ... See full document
7
Original Article Adipose-derived mesenchymal stem cells alleviating heart dysfunction through suppressing MG53 protein in rat model of diabetic cardiomyopathy
... Based on the crucial role of MG53 in the prog- ress of DCM mentioned above, we examined the expression of MG53 and insulin signal pro- teins to explore the mechanism of MSCs work- ing on diabetic ... See full document
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Original Article Ethyl pyruvate reduces hepatic mitochondrial swelling and dysfunction in a rat model of sepsis
... mitochondrial dysfunction may contrib- ute to the pathophysiologic mechanisms under- lying sepsis [2-5], and since EP has been reported to have cytoprotective actions, the aim of the present study was to determine ... See full document
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Original Article Cordyceps sinensis prevents contrast-induced nephropathy in diabetic rats: its underlying mechanism
... elements, can elevate the tol- erance of the body to anoxia and ameliorate poor microcir- culation. Some basic and clin- ical studies have proved its efficacy for treating microcir- culatory disorders. CS can improve ... See full document
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Original Article Cognitive dysfunction and bumetanide treatment in a valproate-induced rat model of autism
... autism rat model, with the expectation that one or more core symptoms of autistic human cognitive obstacles could also be dem- onstrated in ...The mechanism of VPA- induced alterations may occur through ... See full document
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Original Article Mechanism of calcium channel blockers in relieving pathological pain of diabetic peripheral neuropathy in rats
... Abstract: Diabetic neuropathic pain (DNP) is complex and refractory. Commonly used calcium channel blockers (CCBs) can be divided into L type and T type. T type CCB mibefradil can alleviate DNP. However, the role ... See full document
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Original Article Functional mechanism of DPPA in diabetic nephritis via activating AKT signal pathway
... Abstract: Diabetic nephropathy (DN) is a common chronic disease. Diphenyl phosphoryl azide (DPPA) is a type of phosphatidic acid monomer that plays a critical role in regulating Raf-1 translocation and ... See full document
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Original Article The effect of astragalus polysaccharide on the therapeutics of diabetic cardiomyopathy in diabetic rats and its mechanism
... another mechanism of APS therapeutic effects on DC is to reduce Akt phosphorylation, inhibit NF-κb activation, reduce FN and Col III expres- sion, and inhibit accumulation of myocardial ... See full document
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Original Article Effect and mechanism of Huangqi gegen decoction (HGD) on diabetic cardiomyopathy of diabetic rats
... Natural products are considered particularly attractive antiobesity drug candidates because of their higher efficacies and fewer side effects [5]. Chinese medicine comprised of all natural products is widely used to ... See full document
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Original Article Profilin-1 mediates microvascular endothelial dysfunction in diabetic retinopathy through HIF-1α-dependent pathway
... tive diabetic retinopathy (PDR), is a major cause of blindness in the working-age population in developed ...thelial dysfunction (MVED) is simultaneously a prevalent complication of both type 1 and type 2 ... See full document
9
Original Article Study on inhibitory effect of metformin in bladder cancer and its mechanism
... with bladder cancer that consulted at clinic are mostly with non-muscle invasive bladder cancer, and transurethral resection of bladder tumor (TUR-Bt) [2] is the main method to treat the ...invasive ... See full document
7
Study of the mechanism of sonodynamic therapy in a rat glioma model
... After treatment with SDT, at the examined time points, the rat tumors were excised then fixed in 4% paraformaldehyde, paraf- fin embedded, and sectioned through the area of US irradiation. TUNEL (terminal ... See full document
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Cyclic nucleotide metabolism in the streptozotocin diabetic rat corpus cavernosum; Relevance to human diabetic erectile dysfunction
... For much of this century it was thought that ED was predominantly the result of psychological factors or psychogenic in aetiology; over the past two decades it has become increasingly recognised that there are a large ... See full document
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Original Article Protective effects of calcitriol on diabetic nephropathy are mediated by down regulation of TGF-β1 and CIP4 in diabetic nephropathy rat
... streptozotocin injection, diabetes was diag- nosed when their random blood glucose levels over 16.7 mmol/L for 3 days [17]. Another 8-week of high-fat diet was continued, main- taining blood glucose >16.7 mmol/L. At ... See full document
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Original Article Piwil 2 gene transfection changes the autophagy status in a rat model of diabetic nephropathy
... [1-3]. Diabetic nephropathy [DN] is a serious complication of diabetes mellitus, wh- ich is also the most prevalent reason for the end stage renal disease (ESRD) ... See full document
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