[PDF] Top 20 Original Article microRNA-21 is a potential indicator for the pathological progression of cervical cancer

... The tissue samples were ground in liquid nitro- gen and miRNAs were extracted using miR- Neasy Mini Kit (Qiagen, Shenzhen, China) according to the manufacturer’s instructions. Reverse transcription was performed using ... See full document

... vical cancer remains difficult to ...its potential utility for tumor invasion and metastasis [27] and prognostic markers has emerged ...breast cancer patients [28], could exert significant influence ... See full document

... different pathological processes of carcinogen- esis according to down-regulating target gene expression, meanwhile, they also can be modu- lated by upstream regulators, such as tran- scription factors or ... See full document

... tumor progression [14, ...pancreatic cancer are largely uncle- ...pancreatic cancer have been also studied ex- ...pancreatic cancer [18]. The miRNA-21 has been detected to be ... See full document

... in cervical can- cer ...in cervical cancer tissues in compared with the matched adjacent normal cervical ...in cervical cancer tissues, while the nucleus and membrane showed few ... See full document

... gastric cancer patients and healthy controls were ...gastric cancer patients compared to that in healthy individuals which was similar to the previous studies [20, ...the progression of gastric ... See full document

... The microRNA microarray gene expression ex- periments and data analysis were conducted by Suzhou GenePharma Co., Ltd. (Suzhou, China). Total RNA was extracted from the cell lines and frozen tissue specimens with ... See full document

... Abstract: MicroRNA (miR)-429 has been frequently reported to be involved in various tumors including lung ...lung cancer (NSCLC) still remains ...lung cancer (NSCLC) patients comparing adjacent ... See full document

... Purpose: MicroRNA (miR)-211 was previously identified as a candidate biomarker for screening gastric cancer (GC) samples from noncancerous gastric samples based on miRNA microarray expression ...aggressive ... See full document

... and development of malignant tumors through regulation of tumor suppressor genes and oncogenes [21, 22]. More importantly, accumu- lated studies have demonstrated that miRNAs play important functions in ovarian ... See full document

... the progression of human ...in cervical cancer remain ...in cervical cancer cell lines, discussing whether it could be a therapeutic biomarker of cervical cancer in the ... See full document

... tumor progression, metasta- sis and induce resistance to anti-tumor therapy through regulating various targets, including Wnt5a [35], IGF1R [19], and PTEN signaling ... See full document

... colorectal cancer and can promote cell proliferation and invasion [23, ...Caski cervical cancer cells [26]. In gastric cancer, decreasing the expression of miR-155-5p is associated with ... See full document

... cellular microRNA expression, the analysis was performed in positive HPV and negative HPV cell lines, which found that the expression of miR-21 in HPV16 positive group was higher than those in negative ... See full document

... human cervical cancer ...human cervical cancer ...in cervical cancer, such as miR-10a, miR-31, miR-196a, and so on ...sent potential molecular targets to be investi- ... See full document

... gastric cancer, while downregulation of EIF5A2 by miR-30b targeting suppresses tumor migration and invasion in gastric cancer cells ...enhance cancer cell migration and inva- sion of hepatocellular ... See full document

... Abstract: The non-small cell lung cancer (NSCLC) is among the lethal malignancies with high metastasis and recur- rence. The microRNAs are classified into noncoding RNAs and dictate various biological processes. ... See full document

... the original antibody for 1 h in a water bath at 56°C and then for 10 min in dehydrated alcohol to removing the red reaction, so that the sections could be used ... See full document

... and the dysregulation of Dicer may be impor- tant in tumor transformation. Our results were consistent with some of the previous reports as reduction of Dicer was found in NSCLC, breast cancers as well as ovarian ... See full document

... The prostate cancer (PCa) is among the leading causes of tumors in men and about 1/4 of total cases can be ascribed to prostate cancer [1]. Multiple treatment strategies can be obtained for PCa and the five ... See full document