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[PDF] Top 20 Original Article MLLT3 promotes proliferation of osteosarcoma cells by regulating JNK signaling

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Original Article MLLT3 promotes proliferation of osteosarcoma cells by regulating JNK signaling

Original Article MLLT3 promotes proliferation of osteosarcoma cells by regulating JNK signaling

... HOS cells when MLLT3 was knocked down. MLL-MLLT3 fusion was shown to induce activation of RacGTPase through Frat2 in leukemia ...about MLLT3 was reported in solid ...in MLLT3-siRNA- ... See full document

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Original Article Effect of FGFR2IIIc S252W overexpression upon osteosarcoma U2OS cell proliferation via activating ERK1/2 and JNK signaling pathways

Original Article Effect of FGFR2IIIc S252W overexpression upon osteosarcoma U2OS cell proliferation via activating ERK1/2 and JNK signaling pathways

... U2OS cells were fed in a 6-well plate the day before transfected at 80% confluence in suspension ...to cells by Lipofectime 2000TM following the manufac- tures’ protocols of ... See full document

9

Original Article Silencing CCAT2 inhibited proliferation and invasion of epithelial ovarian carcinoma cells by regulating Wnt signaling pathway

Original Article Silencing CCAT2 inhibited proliferation and invasion of epithelial ovarian carcinoma cells by regulating Wnt signaling pathway

... Wnt signaling pathway ...CCAT2 promotes ovarian cancer progression, EOC cells were treated with LiCl to activate canonical Wnt/β-catenin signaling ...Wnt signaling pathway in EOC ... See full document

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Original Article Crosstalk between Hh and Wnt signaling promotes osteosarcoma progression

Original Article Crosstalk between Hh and Wnt signaling promotes osteosarcoma progression

... Objective: Osteosarcoma (OS) is the most common primary malignant tumor of ...ized osteosarcoma are routinely treated with chemotherapy and ...human osteosarcoma cell lines U2OS, SaOS and human ... See full document

6

<p>SRPX2 Promotes Cell Proliferation and Invasion in Osteosarcoma Through Regulating Hippo Signaling Pathway</p>

<p>SRPX2 Promotes Cell Proliferation and Invasion in Osteosarcoma Through Regulating Hippo Signaling Pathway</p>

... leukemia cells and plays a crucial part in regulating cellular migration and adhesion in gastric ...adhesion, proliferation, and ...in osteosarcoma and under- stand its ... See full document

13

Original Article ROR1 promotes the proliferation of endometrial cancer cells

Original Article ROR1 promotes the proliferation of endometrial cancer cells

... Wnt/β-catenin signaling pathway plays a key role in regulating carcinogenesis, and the noncanonical Wnt5a-ROR1 pathway is an important regulator of Wnt ...EC cells in M phase of the cell ...EC ... See full document

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Original Article FoxC1 promotes osteosarcoma cell proliferation and metastasis through the activation of EZH2

Original Article FoxC1 promotes osteosarcoma cell proliferation and metastasis through the activation of EZH2

... Saos-2 cells (Figure 4A) and U2OS cells (Figure 4B) to search the potential targets of ...different signaling pathway were chosen, compared with the normal IgG, FoxC1 has obviously enrich- ment on ... See full document

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Original Article Up-regulated expression of lncRNA NEAT1 promotes progression of osteosarcoma by regulating the activity of Wnt/β-catenin pathway

Original Article Up-regulated expression of lncRNA NEAT1 promotes progression of osteosarcoma by regulating the activity of Wnt/β-catenin pathway

... on osteosarcoma (OS) have not been studied ...Cell proliferation was determined by using both CCK-8 assay and EdU ...cell proliferation, migration and ...Wnt/β-catenin signaling pathway ... See full document

7

Original Article Folate receptor alpha promotes endometrial carcinoma cell proliferation and inhibits apoptosis by regulating the ERK signaling pathway

Original Article Folate receptor alpha promotes endometrial carcinoma cell proliferation and inhibits apoptosis by regulating the ERK signaling pathway

... ERK signaling pathway through the non-receptor tyrosine kinase ...ERK signaling pathway in the pathogenesis of endometrial carcinoma are still ...epithelial cells and different differentiation ... See full document

8

Original Article MiR-145 facilitates proliferation and migration of endothelial progenitor cells and recanalization of arterial thrombosis in cerebral infarction mice via JNK signal pathway

Original Article MiR-145 facilitates proliferation and migration of endothelial progenitor cells and recanalization of arterial thrombosis in cerebral infarction mice via JNK signal pathway

... in regulating EPC growth, proliferation and migration, but without clinical samples from cerebral infarction patients [26] as supporting evidence to show the relationship between EPCs growth and miR- 145 ... See full document

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Original Article Low-expression of miR-7 promotes cell proliferation and exhibits prognostic value in osteosarcoma patients

Original Article Low-expression of miR-7 promotes cell proliferation and exhibits prognostic value in osteosarcoma patients

... by regulating the IGF- 1R/Akt signaling pathway in the study of Wang et al [25, ...through regulating the PI3K/Akt/ mTOR-signaling pathway ...cell proliferation as well as increased ... See full document

7

Original Article MiR-9 promotes proliferation of glioma cells by regulating Foxo3a-p27kip1 signaling axis

Original Article MiR-9 promotes proliferation of glioma cells by regulating Foxo3a-p27kip1 signaling axis

... HEB cells, the expression of miR-9 in glioma Hs683 and SHG44 cells was significantly increased, while the expression of Foxo3a was significant- ly decreased, further suggesting increased miR- 9 expression ... See full document

8

Original Article Inhibition of proliferation and migration of osteosarcoma cells U2OS by phenformin

Original Article Inhibition of proliferation and migration of osteosarcoma cells U2OS by phenformin

... of osteosarcoma patients has been improved dramatically during the late 20th cen- tury ...for osteosarcoma, it still has one of the lowest sur- vival rates for pediatric ... See full document

8

Original Article MLF1IP promotes cells proliferation and apoptosis by regulating CyclinD1 in breast cancer

Original Article MLF1IP promotes cells proliferation and apoptosis by regulating CyclinD1 in breast cancer

... Abstract: Breast cancer is the most frequently diagnosed cancer and the leading causes of cancer death among females in worldwide. It is urgent to develop novel biomarkers to improve risk stratification and optimize ... See full document

9

Original Article ClC-3 chloride channel modulates the proliferation and migration of osteosarcoma cells via AKT/GSK3β signaling pathway

Original Article ClC-3 chloride channel modulates the proliferation and migration of osteosarcoma cells via AKT/GSK3β signaling pathway

... excessive proliferation of cells is closely related to ...cell proliferation accompany with changes in cell volume and the activity of VRCC (volume regulated chloride channel, ...of cells ... See full document

9

Original Article Interleukin-26 promotes the proliferation and activation of hepatic stellate cells to exacerbate liver fibrosis by the TGF-β1/Smad2 signaling pathway

Original Article Interleukin-26 promotes the proliferation and activation of hepatic stellate cells to exacerbate liver fibrosis by the TGF-β1/Smad2 signaling pathway

... stellate cells (HSCs) and the deposition of extra cellular matrix ...the proliferation of HSCs by increasing S phase and decreasing G0/G1 ...the proliferation and activation of HSCs in liver fibrosis ... See full document

9

Krüppel-like factor 4 promotes human osteosarcoma growth and metastasis via regulating CRYAB expression

Krüppel-like factor 4 promotes human osteosarcoma growth and metastasis via regulating CRYAB expression

... MG63 cells. To generate lentivirus expressing KLF4, HEK 293T cells grown on a 6 cm dish were transfected with 2 ug pCDH-Flag-KLF4 or control vector, ...transfection, cells were cultured with DMEM ... See full document

11

RIP3 promotes colitis-associated colorectal cancer by controlling tumor cell proliferation and CXCL1-induced immune suppression

RIP3 promotes colitis-associated colorectal cancer by controlling tumor cell proliferation and CXCL1-induced immune suppression

... progenitor cells and that the release of IL-1β by dying cells and subsequent activation of the inflammasome promote differentiation of leukemia-initiating cells ...tumor cells in hematopoietic ... See full document

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Original Article Estrogen receptor ESR1 promotes BMSCs cell proliferation and migration via regulation of SDF-1/CXCR4 signaling

Original Article Estrogen receptor ESR1 promotes BMSCs cell proliferation and migration via regulation of SDF-1/CXCR4 signaling

... the cells at 4°C overnight. The cells were then resuspended in the mixture of 50 mg/ml propidium iodide (PI; Sigma-Aldrich) and 100 mg/ml DNase-free RNase and cultured for half an hour in dark at ...stained ... See full document

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ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p

ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p

... in osteosarcoma cells compared with that in ...promoted osteosarcoma cell growth, migration, and ...E-cadherin/β-catenin signaling pathway, as evidenced by increased the level of E-cadherin, ... See full document

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