[PDF] Top 20 Original Article Prognostic value of Thy1 in non-small cell lung cancer: a RNA-Seq transcriptome analysis

... total RNA samples were extracted from the sphere 95D cells and adherence 95D cells using TRIzol Reagent (Invitrogen, ...total RNA by the oligo (dT) magnetic ...aligne RNA-seq reads to genome ... See full document

... the prognostic significance of LOX in non-small cell lung cancer (NSCLC) patients and to examine the correlation between LOX expression and ECM remodeling-associated MMP2/MMP9 in ... See full document

... A total of 11 publications met the criteria for this analysis [10-20] (Figure 1). The total num- ber of patients was 1004, ranging from 50 to 161 patients per study. Main characteristics of the eligible studies ... See full document

... the analysis into IIIa>10% and <10% groups, the heterogeneity for OS could shrink slightly to ...cut-off value of the vessel ...the original study, which leads to another source of ...p ... See full document

... the prognostic value of CXCR4 in a more homogenous population of patients with advanced NSCLC is important to eliminate the interference of any other treatment ... See full document

... adjacent non-tumor ...survival analysis revealed that patients with high HOXA-AS2 expression have worse survival ...the prognostic role of HOXA-AS2 ...independent prognostic factor for OS, DFS ... See full document

... Long non-coding RNAs (lncRNAs) XIST and HIF1A-AS1 have been shown to play important regu- latory roles in cancer biology, and lncRNA-XIST and HIF1A-AS1 are upregulated in several cancers such as glio- ... See full document

... potential prognostic biomarkers for prognosis (Table 3). Our meta-analysis looked into six lncRNAs (PVT1, AFAP1-AS1, LINC01133 and ANRIL, UCA1, MALAT-1, MEG3) whose prognostic roles have been clearly ... See full document

... epithelial cancer development ...tric cancer. Moreover, programmed cell death protein ligand 1 (PD-L1) expression has been shown to be regulated by the oncogenic driv- er EGFR in ... See full document

... an original paper (2) expression levels of CD44 were compared to patient’s overall sur- vival; (3) expression of the proteins were evalu- ated in tumor tissues by immunohistochemis- try (IHC) or reverse ... See full document

... regression analysis, respectively. Kaplan-Meier analysis and log- rank tests were used to depict survival curves and compare OS between different ...bone, lung, pleu- ra, liver, lymph nodes, others, ... See full document

... are small non-coding RNAs that negatively regulate gene expression through com- plementarity between the miRNA seed sequence and the target mRNA 3 ′ untranslated region (UTR) ...micro- RNA-126 ... See full document

... Total RNA was extracted from 44 freshly frozen lung tissues, including 22 NSCLC tissues and 22 matched non-cancerous tissue ...(qRT-PCR) analysis was conducted with LightCycler Fast Start DNA ... See full document

... regression analysis was conducted to assess the association between each potential prog- nostic factors including all the clinicopathologi- cal factors and overall survival ...Data analysis was performed ... See full document

... a cancer suppressor in the carcinogenesis in ...in cancer cells [21], and this well explained that the loss of Per may cause the resistance to the apoptosis in the poor dif- ferentiated ...the cancer ... See full document

... Angiopoietin-1 (Ang-1) and Ang-2 are ligands for the tyrosine kinase receptor Tie2; they are not only widely expressed on many embryonic tissues, but also expressed on some cancer cells. There is a complicated and ... See full document

... From the current study, the most important finding was that the patients in group A as compared with group B were less likely to have a tumor relapse (Table 1). However, the effect of metformin treatment on diabetic ... See full document

... the RNA sequencing technology has greatly facilitated identifying lncRNAs associated with various ...contrast, RNA-Seq enjoys a number of advantages, including very low background signal and large ... See full document

... decreases cell invasion To explore the potential functional role of MALAT1 in lung cancer, we suppressed the expression of MALAT1 by RNA interference in lung cancer ...of ... See full document

... as cell free DNA (cfDNA) is a potential marker which was discovered in 1948 by Mandel and ...in cancer patients was published in the seventies ...in cancer patients has been in- vestigated in several ... See full document