[PDF] Top 20 Original Article Prognostic values of EphB1/B2 and p-EphB1/B2 expression in non-small cell lung cancer

... influences cancer metas- tasis, angiogenesis and invasion, and correlat- ed with patients’ clinicopathological characte- ristics in several cancers ...decreased expression level of EphB1 was detected ... See full document

... of lung can- ...squamous cell carcinoma and 30% of the tumors were ...squamous cell carcinoma, 52% were adenocarcinoma, and 4% were ade- nosquamous cell carcinoma (p = ...high-VEGF ... See full document

... RNA was extracted from formalin- fixed tissues, using TRIzol reagent, PureLink™ FFPE RNA Isolation Kit and mirVana PARIS kit (Life Technology, California, USA). RNA was diluted in RNase-free water and stored at -80°C ... See full document

... mRNA expression of individual GPx members to relapse-free ...gene expression data and survival information of 1,926 NSCLC patients down- loaded from Gene Expression Omnibus ...mRNA expression ... See full document

... TP53, one of the most important tumor sup- pressor genes, has been reported to be mutat- ed in over 50% of all human malignant tumors [16], with about 50% of NSCLC harboring TP53 mutations [17, 18]. The prognostic ... See full document

... gene expression levels were normalized to reads per kilowatt of exon model (RPKM) per million mapped reads in order to help for the comparison of transcripts between ... See full document

... Our results indicate that advanced NSCLC patients with GPS 2, receiving platinum-based first-line chemotherapy, were at a higher risk of disease progression and mortality. Moreover, advanced NSCLC patients with GPS 1 ... See full document

... [4] Ettinger DS, Wood DE, Akerley W, Bazhenova LA, Borghaei H, Camidge DR, Cheney RT, Chirieac LR, D’Amico TA, Demmy TL, Dilling TJ, Govindan R, Grannis FJ, Horn L, Jahan TM, Komaki R, Kris MG, Krug LM, Lackner RP, ... See full document

... with small cell lung cancer or lung sarcoma; 3) had distant metastasis before initial surgery (pathologic M stage was 2); or 4) died within 30 days of resec- ... See full document

... Against Cancer (UICC) these specimens were divided into: stage I + stage II (81 cases), stage III + stage IV (117 ...normal lung tissues of which the distance from the tumor site was greater than ... See full document

... HMGB1 is up-regulated in NSCLC patients Twenty-six articles were assessed by titles or abstracts in PubMed, Embase, Cochrane Library and CNKI databases (see Figure 1). After the main texts were checked carefully, 14 ... See full document

... Lung cancer is the leading cause of cancer- related mortality worldwide, which is expected to represent 26% of all female cancer deaths and 29% of all male cancer deaths in 2012 ...[1]. ... See full document

... Lung cancer is the most common cause of can- cer deaths worldwide [1]. Non-small cell lung cancer (NSCLC) is the most frequent type of lung cancer, ... See full document

... went surgery for histologically verified NSCLC at the Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, between 2007 and 2009 were enrolled in this ... See full document

... Abstract: Lung cancer has some of the highest morbidity and ...YAP expression in 81 non-small cell lung cancer cases that received surgery, and we discuss the ... See full document

... the expression of tumor suppressor candidate 3 (TUSC3) in non-small cell lung can- cer (NSCLC) compared to adjacent normal tissue, and its correlation with patients’ clinicopathological ... See full document

... prostate cancer [24], colorectal cancer [25], gastric cancer [26], and ovarian cancer ...EphA2 expression is correlated with disease stage, increased tumor metastasis, and poor patient ... See full document

... the prognostic role of serum miR- 141 expression in ...both lung adenocar- cinoma patients (N=49) and lung SCC patients ...(N=52). Lung adenocarcinoma pati- ents with miR-141 low ... See full document

... Data were presented as numbers of subjects (percentage) for categorical variables. The cor- relations of the expression of biomarkers and the clinicopathological characteristics of the patients were assessed by ... See full document

... Lung cancer, the most commonly diagnosed malignant tumor, is the leading cause of death among the malignant tumors throughout the world ...of lung cancer is still increasing in China due to ... See full document