[PDF] Top 20 Original Article SKA1 promotes the proliferation of osteosarcoma cell through AKT activation and regulates the expression of cyclins
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Original Article SKA1 promotes the proliferation of osteosarcoma cell through AKT activation and regulates the expression of cyclins
... with AKT activities. Furthermore, block- ing the Ska1/Akt signaling pathway induces anti-proliferation and anti-invasion properties in OS ...between Ska1 and AKT-related ... See full document
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Original Article MicroRNA-196a overexpression promotes cell proliferation and inhibits cell apoptosis through PTEN/Akt/FOXO1 pathway
... promoted cell proliferation in both MG-63 and U2OS cells, we assumed that miR-196a could accelerate the cell cycle of OS ...the proliferation of osteosarcoma cells by promoting the G1/S ... See full document
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Original Article ClC-3 chloride channel modulates the proliferation and migration of osteosarcoma cells via AKT/GSK3β signaling pathway
... the osteosarcoma cell proliferation and migration, we observed the effect of ClC-3 knockout on the cell cycle of MG-63 and 143B ...arrested cell cycle in G0/G1 phase both in MG-63 and ... See full document
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Original Article MAPK1 up-regulates the expression of MALAT1 to promote the proliferation of cardiomyocytes through PI3K/AKT signaling pathway
... the expression of LncRNA MALAT1; moreover, MAPK1 was able to up-reg- ulate the expression of MALAT1 via activating PI3K/AKT signaling in H9C2 ...that promotes proliferation of ... See full document
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Original Article Dipalmitoylphosphatidic acid reduces osteosarcoma growth by activation of AKT signaling pathway
... tumor proliferation by silencing UspA2 gene expression in ...of osteosarcoma. Therefore, the osteosarcoma model was established by using ...18]. Akt is an important gene and plays a key ... See full document
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Original Article Carboxymethylated chitosan promotes Schwann cell proliferation and expression of neurotrophic factors by activation of PKA and PKC signaling pathways
... that regulates the expres- sion of genes involved in neuronal survival and function ...increase expression of cAMP, and acti- vate PKA activity, increase CREB and p-CREB expression by western blot ... See full document
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Original Article MiR-135 post-transcriptionally regulates FOXO1 expression and promotes cell proliferation in human malignant melanoma cells
... gene expression by targeted repression of transcription and translation and play es- sential roles during cancer ...and cell lines by using Real-time PCR assay. Enforced expression of miR-135a in ... See full document
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Original Article MLLT3 promotes proliferation of osteosarcoma cells by regulating JNK signaling
... induce activation of RacGTPase through Frat2 in leukemia ...the expression of c-Jun, BCL-2, Akt was significantly decreased in MLLT3-siRNA- treated HOS ...the activation of JNK- ... See full document
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Original Article HOXB5 mRNA is upregulated in osteosarcoma tissues and promotes osteosarcoma cell line proliferation in vitro
... which regulates transcription and has important effects on morphogenesis and differentiation during embryonic ...the expression of HOXB5 mRNA in osteosarcoma and normal tissue/cell lines, as ... See full document
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Original Article Low-expression of miR-7 promotes cell proliferation and exhibits prognostic value in osteosarcoma patients
... IGF1-induced activation of AKT leading to the inhibition of cell prolifera- tion and cell-cycle arrest, and an enhanced apoptotic rate in the study of Jiang et al ...carcinoma through ... See full document
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Original Article FoxC1 promotes osteosarcoma cell proliferation and metastasis through the activation of EZH2
... of osteosarcoma proliferation, migration and invasion remains to be eluci- ...of osteosarcoma cell proliferation and metastasis and to assess its role as potential therapeutic ...both ... See full document
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<p>LINC01535 Promotes the Development of Osteosarcoma Through Modulating miR-214-3p/KCNC4 Axis</p>
... the proliferation, apoptosis, migration and invasion of various tumor ...exacerbates cell pro- liferation and invasion in colorectal ...hastens cell cycle and migration and predicts a poor prognosis ... See full document
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Original Article Decreased expression of long noncoding RNA NBAT1 indicates a poor prognosis and promotes cell proliferation and EMT in bladder cancer
... NBAT1 expression is dramatically down-regulated in BCa tissues and cell ...NBAT1 expression was significantly associated with tumor grade, tu- mor stage and overall survival of BCa patients, ... See full document
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Cdks, cyclins and CKIs: roles beyond cell cycle regulation
... stem cell self-renewal are two closely related ...of cell cycle regulation characterized by rapidly alternating rounds of S and M phases that are interspersed by short gap phases (Becker et ...in ... See full document
15
Decreased SATB1 expression promotes AML cell proliferation through NF-κB activation
... The invasive potential of HL-60 SATB1-shRNA1 cells, HL-60 SATB1-shRNA2 cells was examined using tran- swell inserts fitted with polycarbonate filters (8-μm pore size, Costar, Cambridge, MA) coated with matrigel (BD ... See full document
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Panax notoginseng saponins promote liver regeneration through activation of the PI3K/AKT/mTOR cell proliferation pathway and upregulation of the AKT/Bad cell survival pathway in mice
... ginsenoside Rg1, Rd., Re and Rb1 are the major active com- ponents [4–6]. More than 200 compounds have been iso- lated from PNS, including saponins, flavonoids, cyclopeptides, sterols, polyacetylenes, volatile oil, amino ... See full document
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Original Article Osteoprotegerin promotes islet β cell proliferation in intrauterine growth retardation rats through the PI3K/AKT/FoxO1 pathway
... β cell function [9, 12, ...prevent cell death in human and rat β cells ...β cell mass in young, aged, and STZ (Strepto- zotocin)-treated diabetic mice ... See full document
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Original Article Increased expression of RACK1 promotes cell proliferation and indicates a poor prognosis in patients with laryngeal squamous cell carcinoma
... Laryngeal malignancies are the second most common cancers of the head and neck, and more than 95% of cases worldwide are diag- nosed as laryngeal squamous cell carcinoma (LSCC) [1, 2]. Now, the main treatment for ... See full document
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Original Article MicroRNA-181b promotes osteosarcoma cell proliferation, invasion and migration in vitro via targeting RASSF8
... enhancing cell motility and invasiveness and by increasing lymphangiogenesis via the NF-κB/VEGF-C axis ...tion through increasing p53 and p21 expres- ...OS proliferation, invasion and migra- tion ... See full document
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Original Article Inhibition of LN-308 glioma cell proliferation and migration by retinoic acid amide through activation of Akt pathway
... well were dispersed onto 48-well plates and allowed to attain confluence. RAA at various concentrations was added to each well fol- lowed by incubation for 48 h. After incubation, pipette tip was pierced gently into the ... See full document
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