[PDF] Top 20 Original Article Reduced expression of miR-26b is associated with poor prognosis of osteosarcoma

... that miR-26b is a tumor suppressor in all types of cancers investigated so far, indicating the biological function of miR-26b is highly con- served and it might play a key role in the ... See full document

... of miR-381 in PTC. In this study, we found that serum miR-381 expression was significantly downregulated in PTC patients compared to that of BTN patients or healthy ...lower miR-381 ... See full document

... serum miR-21 expression than those who were res- ponse to chemotherapy ...serum miR-21 level was able to distin- guish the NPC patient resistant to cisplatin based chemotherapy from those patients ... See full document

... end of the second month, she had petechiae and ecchymoses all over the body and the platelet count decreased gradually. As her rehospitalization, we found although she had no sputum-coughing without fever, her was ... See full document

... the expression level of SCUBE2 in 124 GC patients, and the results were consistent with the findings of Western ...SCUBE2 expression was sig- nificantly associated with advanced clinical stage, T4 or ... See full document

... in poor prognosis for patients with gastric cancer ...that miR-506 inhibited vimentin and N-cad in the epithelial mesenchymal transition network and decreased expression of miR-506 was ... See full document

... of miR-497 was cor- related with breast cancer progression, and miR-497 might be a potential molecular bio- marker for predicting the prognosis of patients ...that miR-497 was down- regulated ... See full document

... MEG3 expression level and the prognosis of osteosarcoma is still ...The expression levels of lncRNA MEG3 in osteosarcoma tissues and adjacent non-tumor tissues were detected using ... See full document

... Osteosarcoma (OS), a common primary bone tumor, often occurs in the long bones (inferior femora and superior shinbones) of children and adolescents [1]. Most patients are at II B stag- es when they are initially ... See full document

... Cutaneous malignant melanoma represents the primary cause of death among skin cancers and its incidence rate is increasing in recent years [1]. Most melanomas could detect at early stage but once it develops to the meta- ... See full document

... human osteosarcoma remains unknown. Methods: LncRNA HULC expression in osteosarcoma tissues and cell lines was detected by quantitative real-time ...of osteosarcoma patients was performed by ... See full document

... Despite the incidence of gastric cancer (GC) has been decreasing, it remains globally the fifth most commonly cancer and the second leading cause of cancer-related mortality world- wide, especially in east Asia [1]. Most ... See full document

... of miR-204 may promote the invasive prop- erty of breast ...regulated miR-204 may be related to the onset of gastric cancer metastasis ...that miR-204 was reduced in glioma with aberrantly ... See full document

... [14-18]. miR-218 precursors, miR-218-1 and miR-218-2, are produced from two different genomic ...Both miR-218-1 and miR-218-2 are located in the intronic regions of the SLIT2 gene on ... See full document

... serum miR-138 expression was remarkably reduced in HNSCC patients compared to healthy ...serum miR-138 levels were significantly elevat- ed in post-operative blood samples taken from patients ... See full document

... cellular miR-647, the reverse transcription reaction was undertaken using a Taqman MicroRNA Reverse Transcription Kit (Applied Biosystems, Foster City, CA, ...Gene expression was normalized against ... See full document

... The TMA, involving a total of 197 CRC patients who under- went colorectal resections from November 2013 to June 2014 in Nanfang Hospital, Southern Medical University (Guangzhou, China), was applied to analyze the ... See full document

... Total RNA from tissues or cell lines was extracted with Trizol reagent (Takara, Shiga, Japan) according to the manufacturer’s instructions. mRNA was reverse transcribed by using a Prime- Script RT reagent Kit (Takara). ... See full document

... Tiam1 expression, those with low Tiam1 expression had a longer 5-year overall ...Tiam1 expression was an independent risk factor for poor prognosis, along with lymph node ... See full document

... with poor overall survival of GC patients (p = 0.005). The data were divided into subgroups according to the TNM stage. The 5-year survival rates were 97.6% and 95.8% in low and high eIF3d patients, respectively ... See full document