[PDF] Top 20 Pestivirus Internal Ribosome Entry Site (IRES) Structure and Function: Elements in the 5′ Untranslated Region Important for IRES Function
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Pestivirus Internal Ribosome Entry Site (IRES) Structure and Function: Elements in the 5′ Untranslated Region Important for IRES Function
... the 5 ⴕ untranslated region of classical swine fever virus (CSFV) RNA for the function of the internal ribosome entry site (IRES) was investigated by ... See full document
10
The Hepatitis C Virus RNA 3′-Untranslated Region Strongly Enhances Translation Directed by the Internal Ribosome Entry Site
... by 5 ⴕ - and 3 ⴕ -untranslated regions ...the internal ribosome entry site (IRES) in the 5 ⴕ -UTR, and subsequent viral RNA replication requires sequences in the 3 ... See full document
10
The 5′ Untranslated Region of Rhopalosiphum padi Virus Contains an Internal Ribosome Entry Site Which Functions Efficiently in Mammalian, Plant, and Insect Translation Systems
... an internal ribosome entry site (IRES) element within the 5⬘ UTR of the genome (reviewed in refer- ences 2 and ...Picornavirus IRES elements are grouped into two ... See full document
6
Hepatitis C Virus Internal Ribosome Entry Site (IRES) Stem Loop IIId Contains a Phylogenetically Conserved GGG Triplet Essential for Translation and IRES Folding
... reduce IRES activity. Inhibition studies of the HCV IRES IIId region were carried out using morpholino antisense oligonucleotides which have been previ- ously shown to work in an RNase H-independent ... See full document
8
A Phylogenetically Conserved Stem-Loop Structure at the 5′ Border of the Internal Ribosome Entry Site of Hepatitis C Virus Is Required for Cap-Independent Viral Translation
... HCV IRES have been carried out in a number of laboratories (1, 6, 9, 11, 14–19, ...secondary structure of the 59NTR of HCV that was proposed by Brown et ...genus Pestivirus (bovine viral diar- rhea ... See full document
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Viral Internal Ribosome Entry Site Elements: Novel Ribosome-RNA Complexes and Roles in Viral Pathogenesis
... ternal ribosome entry site elements, commonly abbreviated as IRES elements, in their 5⬘ noncoding regions that can directly recruit ribosomal 40S subunits with a reduced ... See full document
6
In Vivo and In Vitro Identification of Structural and Sequence Elements of the Human Parechovirus 5′ Untranslated Region Required for Internal Initiation
... therefore important to have a fuller understanding of its molecular bi- ology, which will also contribute to our understanding of func- tional conservation and diversity of ...the 5⬘UTR, including what is ... See full document
9
Identification of an essential region for internal initiation of translation in the aphthovirus internal ribosome entry site and implications for viral evolution.
... predicted structure but differed in nucleotide sequence ...in IRES activity in the persistent FMDV variant R100 could be achieved only by the U-to-C substitution but not by the U-to-A or U-to-G substitution ... See full document
7
Natural Occurrence and Characterization of Two Internal Ribosome Entry Site Elements in a Novel Virus, Canine Picodicistrovirus, in the Picornavirus-Like Superfamily
... functional IRES elements, a phenomenon present in members of the Dicistroviridae ...One IRES element is at the 5= untranslated region (UTR) and the other between VP1 and ... See full document
12
Dengue and Zika Virus 5′ Untranslated Regions Harbor Internal Ribosomal Entry Site Functions
... IRES elements are among the most mysterious RNA structures in eukaryotic molec- ular ...an IRES allows initiation of translation of a eukaryotic mRNA independent of the nature of the 5= ... See full document
16
Interaction of Translation Initiation Factor eIF4B with the Poliovirus Internal Ribosome Entry Site
... the internal ribosome entry site ...the 5 ⴕ noncoding region of the viral RNA guides the ribosome to an internal silent ...secondary structure ... See full document
10
Poliovirus Internal Ribosome Entry Segment Structure Alterations That Specifically Affect Function in Neuronal Cells: Molecular Genetic Analysis
... long 5⬘ untranslated region (5⬘-UTR; 742 nucleotides [nt] for PV type 1 Mahoney strain [PV1(M)]) plays different important roles in the PV life ...cloverleaf structure involved ... See full document
10
Mutational Analysis of the Bovine Hepacivirus Internal Ribosome Entry Site
... a 5= and a 3= nontranslated region (NTR) ...The 5= NTR of pestiviruses, pegiviruses, and hepaciviruses, including hepatitis C virus (HCV), GBV-B, and nonprimate hepacivirus (NPHV), contains an ... See full document
13
Structure-function analysis of the equine hepacivirus 5′ untranslated region highlights the conservation of translational mechanisms across the hepaciviruses
... The 5 ′ untranslated regions (UTRs) of both HCV and EHcV exhibit internal ribosome entry site (IRES) activity, allowing cap-independent translational initiation, yet only ... See full document
14
Mechanism of Initiation Site Selection Promoted by the Human Rhinovirus 2 Internal Ribosome Entry Site
... clearly important (though not absolutely essen- tial) for productive recruitment of ribosomes, yet very little initiation occurs at this ...for ribosome re- cruitment suggests that the anticodon of Met-tRNA ... See full document
12
Mutational Analysis of the GB Virus B Internal Ribosome Entry Site
... by internal entry of ribosomes on GBV-B ...mutated 5 ⴕ nontranslated GBV-B RNA (5 ⴕ NTR) segments, placed between the coding sequences of two reporter proteins, in vitro in rabbit reticulocyte ... See full document
11
The 3′-Untranslated Region of Hepatitis C Virus RNA Enhances Translation from an Internal Ribosomal Entry Site
... (X region) at the 3 * -untranslated region (UTR), which assumes a highly conserved stem-loop ...X region binds a polypyrimidine tract-binding protein (PTB), which also binds to the ... See full document
8
The Human Immunodeficiency Virus Type 1gag Gene Encodes an Internal Ribosome Entry Site
... gag 5⬘ UTR can inhibit cap-dependent translation of reporter pro- ...the 5⬘ end of all HIV-1 RNA ...secondary structure at or near the 5⬘ end of RNAs reduces the accessibility of the 5⬘ ... See full document
11
Structural Features of the Seneca Valley Virus Internal Ribosome Entry Site (IRES) Element: a Picornavirus with a Pestivirus-Like IRES
... the 5 ⬘ UTR of the SVV genome, together with 31 to 55 nt of viral coding sequence, contains a functional IRES ...predicted structure and functional properties, the SVV IRES should be placed ... See full document
10
Picornavirus Internal Ribosome Entry Site Elements Target RNA Cleavage Events Induced by the Herpes Simplex Virus Virion Host Shutoff Protein
... cleavage site(s) more precisely, through high-resolution analysis of the cleavage ...the 5⬘-most 156 nt of the EMCV IRES (pCITE RI/AvrII) to char- acterize the 5⬘ ...mutant IRES element ... See full document
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