[PDF] Top 20 Polymorphism in regulatory gene sequences
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Polymorphism in regulatory gene sequences
... Considerable attention recently has focused on polymor- phisms and their potential subtly to alter protein function in ways that might prove biologically or clinically important. But increasing numbers of polymorphisms ... See full document
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Role of transcription regulatory sequence in regulation of gene expression and replication of porcine reproductive and respiratory syndrome virus
... flanking sequences, form secondary structures essential for the sgRNA forma- tion and play an important role in the regulation of viral transcription and translation [8, ...(GFP) gene driven by the body ... See full document
7
High risk for lung and bladder cancers in the Arabian Gulf population associated with EGFR genetic variants regulating expression
... EGFR gene (Liu et ...EGFR gene expression and hence the EGFR cell surface expression (Liu et ...variability, gene amplification and mutations in the EGFR coding region and activation of cell ... See full document
7
Activation of the major immediate early gene of human cytomegalovirus by cis-acting elements in the promoter-regulatory sequence and by virus-specific trans-acting components.
... Therefore, the regulatory sequences of the major immediate early gene of human cytomegalovirus have an important role in interacting with cellular and virus-specific factors of the trans[r] ... See full document
11
Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein
... To determine whether decreased insulin promoter activity might be associated with altered activity of transcription factors that interact with insulin gene regulatory sequences, nuclear [r] ... See full document
7
RESEARCH ARTICLE Association between a single nucleotide polymorphism in neuregulin-1 and schizophrenia in Pakistani patients
... These sequences, from patients and controls, were aligned with the human neuregulin-1-glial growth factor 2 gene sequence, which served as a reference ...nucleotide polymorphism genetic algorithm was ... See full document
6
Patterns of synuclein expression throughout lens development
... the regulatory elements in the promoter of another crystallin gene required for embryonic lens de- velopment- ...-synuclein gene is similar to a part of the PL1 regulatory element in mouse ... See full document
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Diversity of Staphylococcus Species Strains Based on Partial kat (Catalase) Gene Sequences and Design of a PCR Restriction Fragment Length Polymorphism Assay for Identification and Differentiation of Coagulase Positive Species (S aureus, S delphini, S hyicus, S intermedius, S pseudintermedius, and S schleiferi subsp coagulans)
... kat gene sequence similarity and phylogeny derived from kat ...kat sequences (including 17 sequences found in the GenBank and EMBL databases ...katA gene sequences of 30 Staphylococcus ... See full document
10
An arthropod cis-regulatory element functioning in sensory organ precursor development dates back to the Cambrian
... third gene, asense (ase), whose expression is limited to SOPs ...AT-rich sequences, b boxes, of unknown function and N boxes that, in the case of the ac-SOPE, have been shown to bind the transcriptional ... See full document
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Impact of the 216G/T Polymorphism on the Sp1 and Epidermal Growth Factor Receptor Interaction in Non Small Cell Lung Carcinoma
... The regulatory process of EGFR is complex and is based on interactions between the transcriptional factors binding multiple sites found in the promoter region [4], an intronic enhancer element and two enhancer ... See full document
7
Intrahaplotype Polymorphism at the Brassica S Locus
... Nasrallah, Polymorphism of the kinase domain of the S-locus receptor kinase 1991 DNA sequences of self-incompatibility genes from Brassica gene (SRK) in Brassica oleracea ...oleracea: ... See full document
12
Dissecting the regulatory switches of development: lessons from enhancer evolution in Drosophila
... reporter gene constructs to be ...B gene (Celniker et ...functional sequences of the enhancer module are often resolved in detailed transgenic reporter gene studies [for early resolution of ... See full document
9
Identification of sequence requirements and trans-acting functions necessary for regulated expression of a human cytomegalovirus early gene.
... To define important upstream regulatory elements of this gene, we generated hybrid plasmids in which 5'-promoter sequences were fused to the Escherichia coli chloramphenicol acetyltransf[r] ... See full document
11
Activation of the human beta globin promoter in K562 cells by DNA sequences 5' to the fetal gamma or embryonic zeta globin genes
... beta-globin gene in these ...beta-globin gene. The gene appeared to be inducible with ...resistance gene, again in stably transformed ... See full document
8
The malaria candidate vaccine liver stage antigen 3 is highly conserved in Plasmodium falciparum isolates from diverse geographical areas
... The sequences of the full length of the lsa-3 gene from the 20 clinical isolates were compared with the published sequence of the laboratory strain 3D7 ... See full document
7
Phylogenetic Analysis and PCR Restriction Fragment Length Polymorphism Identification of Campylobacter Species Based on Partial groEL Gene Sequences
... groEL gene sequences compared with 16S rRNA gene ...groEL gene sequences is shown in ...groEL gene sequences was similar to that based on the 16S rRNA gene ...rRNA ... See full document
9
Sequences in the polyomavirus DNA regulatory region involved in viral DNA replication and early gene expression.
... 739-749 0022-538X/85/060739-11$02.00/0 Copyright © 1985, American Society for Microbiology Sequences in the Polyomavirus DNA Regulatory Region Involved in Viral DNA Replication and Early[r] ... See full document
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Gene Expression Regulation by the 5' Regulatory Sequences of the Rice rubi3 Gene in Transgenic Rice Plants
... Adh1 gene produced increases in enzyme activity in maize protoplasts that were approximately three times greater than the elevation in mRNA (Mascarenhas et ...Sh1 gene (Clancy and Hannah, 2002), and the ... See full document
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Regulatory sequences of duck hepatitis B virus C gene transcription.
... The 3' end of the C gene promoter region was defined by transfection of liver and nonliver cells with plasmids containing the coding region for CAT as a reporter gene and DHBV DNA fragme[r] ... See full document
9
Intragenic tandem repeats in Daphnia magna: structure, function and distribution
... Primer sequences and PCR conditions for polymor- phic VNTR loci are described in Additional File ...USA). Polymorphism (number of alleles) was assessed at 106 loci, which consistently amplified DNA from all ... See full document
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