Top PDF Postural Changes In Blood Pressure Associated With Ageing

Postural Changes In Blood Pressure Associated With Ageing

Postural Changes In Blood Pressure Associated With Ageing

Alli C et al. 1992; Rutan GH et al. 1992; Räihä I et al. 1995).This phenomenon has been attributed to age associated systolic hypertension (Harris T et al. 1991; Rutan GH et al. 1992; Mukai S and Lipsitz LA, 2002). Older people differ from the young or middle aged adults with the same disease in many ways, one of which is the frequent occurrence of co morbidities and of subclinical disease. A second way in which older adults differ from younger adults is the greater likelihood that their diseases present with nonspecific symptoms and signs (Alagiakrishnan K, 2007).
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Noninvasive Continuous Monitoring of the Effects of Head Position on Brain Hemodynamics in Ventilated Infants

Noninvasive Continuous Monitoring of the Effects of Head Position on Brain Hemodynamics in Ventilated Infants

preceding period of asphyxia. Given the distensibil- ity of the neonatal skull, variations in vascular trans- mural pressure may occur with the changes in blood volume; this effect will be larger with smaller in- creases in intracranial pressure in the case of highly compliant skulls. Obstruction of venous return by an unfavorable head position thus may expose the infant to increased venous volume and pressure, and increase the risk of intracranial bleeding. Al- though we have not found a correlation between postural changes in ⌬ CBV and birth weight, the (⌬CBVlat⫺CBV) changes seemed to be higher in the smallest patients (Fig 4). This may be attributed to their more compliant neck structures, but they also would have more compliant skulls. Changes in ve- nous transmural pressure may be broader in range and the risk of intracranial bleeding could be greater. In our study, there were no simultaneous varia- tions in SaO 2 31 or Pco 2 , 17,32 that could have affected
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General Osteopathic Treatment is Associated with Postural Changes

General Osteopathic Treatment is Associated with Postural Changes

There is increasing pressure on methods of complementary and alternative medicine to adhere to the rules of evidence based medicine [1,2] and to follow the research roadmap for complementary and alternative medicine [3]. Osteopathic manipulation still is under critical scrutiny and needs evidence-based assessment. This treatment has been shown moderately effective in patients with low-back pain, whereby several methods of pain scoring [4-6], pain pressure thresholds [7], neural mechano- sensitivity [8], or biomechanical parameters during flexion were assessed [9]. Also a favourable effect of osteopathic manipulation on cervical hysteresis [10] and inter-vertebral range of motion [11] has been reported.
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Obesity associated to high blood pressure in adolescence

Obesity associated to high blood pressure in adolescence

Findings of the current study, showed that 12,5% of adolescents presented alterations in high blood pressure levels, prevailing male students of the age group from 15 to 16 years old. The association between high blood pressure levels and overweight/obesity had a greater index in males and we highlight the fact that all adolescents classified as obese presented altered high blood pressure. Educational actions in health field should be developed in schools and are essential for a whole education of children and adolescents. In this sense, the intervention of health professionals in actions to build bonds and confidence with adolescents extending it to their family members in terms of behavior changes is extremely important. We highlight the importance of this research for the accomplishment of the early and effective diagnosis monitoring of the cases, as the nurse as a member of the health staff is responsible for the detection and control of the HBP in childhood and adolescence.This professional is also a constant educator, as through its orientations this target public together with its family, school and community, can acquire healthy life habits and contribute for the non-evolution of diseases. Therefore, it is valid to highlight the importance and need of campaigns and educational measures with interventions in the school environment, to turn young people healthier and protagonist in their health selfcare.The study meets the aim developed in the research and contributes significantly for the qualification of health and education professionals being useful as a subsidy for new researchs.
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Treatment of Obese Children With and Without Their Mothers: Changes in Weight and Blood Pressure

Treatment of Obese Children With and Without Their Mothers: Changes in Weight and Blood Pressure

changes in their mothers; and (4) weight losses in obese adolescents are associated with significant decreases in blood pressure, particularly in children. with the highest initial blood[r]

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Blood pressure change does not associate with Center of Pressure movement after postural transition in geriatric outpatients

Blood pressure change does not associate with Center of Pressure movement after postural transition in geriatric outpatients

other aforementioned studies have measured BP inter- mittently [3, 11, 21]. Furthermore, we used a different measure of standing balance, which may also explain the conflicting results. CoP movement portrays the quality of standing balance and can be used as a meas- ure for impaired standing balance [22, 23]. However, CoP movement is an indirect measure of standing bal- ance [31]. In the present study, CoP movement was used as a measure of quality of standing balance, while other studies used CoM movement, as a measure of postural sway by an inclinometric instrument [21], an ataxiameter [3] or the ability to maintain balance dur- ing side-by-side and tandem stance [11, 20]. Further- more, in all, except for one study [11] standing balance was not measured directly after standing up. Measuring standing balance directly after standing up gives the most actual representation of standing balance in daily life. Not measuring standing balance directly after standing up may give results differing from an eco- logical situation. Furthermore, it does not take iOH into account, which is significantly associated with im- paired standing balance in older adults and therefore plays an important role in falling [4, 5].
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Association between antenatal blood pressure and 5-year postpartum retinal arteriolar structural and functional changes

Association between antenatal blood pressure and 5-year postpartum retinal arteriolar structural and functional changes

Table 2 shows the associations of antenatal SBP at baseline and retinal arteriolar structural and functional measures at the 5- year follow- up, which demonstrates step 1 of our planned mediation analysis. After adjustment for age, ethnicity and college degree, each 10 mm Hg increase in baseline SBP was significantly associated with reduced retinal arteriolar calibre (β −1.1 µm; 95% CI −2.2 to 0.04) and fractal dimension (−0.6 degrees of freedom (df); –1.1 to –0.1) and increased arteriolar constriction (0.3%; 0.02 to 0.7). After further adjusting for GDM diagnosis and prepregnancy BMI at baseline, the associ- ations for retinal arteriolar calibre (−1.3 µm; −3.0 to 0.2) and fractal dimension (−0.4 df; −1.0 to 0.2) attenuated to non- significance, while DVA constriction remained significant (0.5%; 0.001 to 1.0). We did not find any significant change on the sensitivity analysis.
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Blood pressure and blood flow variation during postural change from sitting to standing: model development and validation

Blood pressure and blood flow variation during postural change from sitting to standing: model development and validation

To obtain adequate filling of the left ventricle we added a compartment that represents the left atrium. In the 7 compartmental model we used the blood pressure in the upper body to validate the model against data, which are measured in the finger. The pulse pressure (systolic minus diastolic pressure) in the upper body is too wide and very sensitive to parameter changes. Hence, to improve our model we included a compartment that represents the arteries in the finger. In addition, we added two small compartments that represent the aorta and vena cava. These compartments were primarily added to improve model simulation stability. In summary, the improvements discussed above have led to the addition of 4 additional compartments. Furthermore, the 7 compart- mental model was not able to predict pulse pressure reg- ulation immediately following standing. To compensate for this we have modeled resistance of the large arteries using nonlinear functions of pressure. Finally, to obtain accurate widening of the blood flow velocity, a feature that our 7 compartmental model was not able to predict, we devised an empirical model of autoregulation, and a physiological model that can predict pooling of blood in lower extremities, due to effects of gravity.
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CARDIAC OUTPUT IN POSTURAL HYPOTENSION

CARDIAC OUTPUT IN POSTURAL HYPOTENSION

In the over-all view, significant postural falls in blood pressure were more consistently associated with failure of normal arteriolar constriction as indicated by lack of increase in ca[r]

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Treatment of prehypertension: lifestyle and/or medication

Treatment of prehypertension: lifestyle and/or medication

Abstract: Prehypertension is a warning to individuals with resting blood pressures between 120/80 mmHg and 139/89 mmHg of an insidious progression of blood pressure towards hypertensive levels ($140/90 mmHg). Prehypertension is associated with increased cardiovascular risk and end organ damage compared with individuals who are normotensive. This review primarily focuses on internal and external factors associated with the prevalence of prehypertension. Elucidating all of the factors associated with a rise in resting blood pressure and comparing the effects of medication versus lifestyle changes may aid the clinician in developing a preventive and/or treatment strategy for each individual.
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A promoter polymorphism in APJ gene is significantly associated with blood pressure changes and hypertension risk in Chinese women

A promoter polymorphism in APJ gene is significantly associated with blood pressure changes and hypertension risk in Chinese women

The apelin and APJ genes were sequenced by a previous pilot study by Li et al, and 12 common polymorphisms were identified and further genotyped in 1015 Han Chinese from 248 families [11]. Only 5 polymorphisms in apelin/APJ system were significantly associated with hypertension, obesity and onset age of hypertension. The results of this pilot study were subsequently validated by several association studies [10, 12, 15, 23]. However, significant findings are not often reproducible, and no consensus has been reached yet. To deepen our understanding on the genetic contribution of apelin/APJ system, we investigated the association of 5 well-defined polymorphisms with both blood pressure changes and hypertension risk among 650 hypertensive patients and 645 normotensive controls. In addition, we explored whether this association is gender-dependent. Via a comprehensive analysis, we found a predominant role of APJ gene rs7119375 polymorphism in regulating SBP and predisposing to hypertension in women, partly in line with the findings by Niu et al. [12], as the relationship between rs7119375 and blood pressure was not explored. By contrast in the GenSalt study, APJ gene rs7119375 polymorphism was not significantly associated with blood pressure response to potassium supplement [13]. In addition, our allele combination analysis confirmed the leading contribution of this polymorphism to hypertension predisposition. On the basis of these findings, we propose for the first time that the promoter polymorphism rs7119375 in APJ gene is a potential hypertension-
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Consumption of nattokinase is associated with reduced blood pressure and von Willebrand factor, a cardiovascular risk marker: results from a randomized, double-blind, placebo-controlled, multicenter North American clinical trial

Consumption of nattokinase is associated with reduced blood pressure and von Willebrand factor, a cardiovascular risk marker: results from a randomized, double-blind, placebo-controlled, multicenter North American clinical trial

The study population included healthy adults of both sexes, aged 18–85 years, and elevated BP was identified by systolic BP ≥ 130 mmHg or diastolic BP ≥ 90 mmHg, confirmed on three separate occasions. People were excluded from the study if they had consumed nattokinase-containing supplements within 60 days prior to enrollment; were currently on BP medication; had a history of cancer or chemotherapy within the last 12 months; significant active uncontrolled disease; were consuming more than an average of 2 standard alcoholic drinks/d (14 drinks/wk); were currently experiencing intense stressful events/life changes that would negatively affect com- pliance; were pregnant, nursing, or trying to become pregnant; were females not using effective contraception; or had food allergies related to ingredients in test product.
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Changes in Superior Sagittal Sinus Blood Velocities Due to Postural Alterations and Pressure on the Head of the Newborn Infant

Changes in Superior Sagittal Sinus Blood Velocities Due to Postural Alterations and Pressure on the Head of the Newborn Infant

S Results when baby lies supine in positions I (head in the midline and neck flexed), III (head turned 90 degrees to the right), and IV (head turned 90 degrees to the left), and results [r]

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<p>Blood Pressure is Associated with Rapid Kidney Function Decline in a Very Elderly Hypertensive Chinese Population</p>

<p>Blood Pressure is Associated with Rapid Kidney Function Decline in a Very Elderly Hypertensive Chinese Population</p>

Multiple mechanisms have the potential to contribute to the observed relationship between hypertension and elevated RKFD risk. Hypertension-associated rises in intraglomerular pressure are common, 17 and have the potential to induce or exacerbate glomerular and intersti- tial fibrosis. 1 Such fibrosis can, in turn, drive renal ische- mia and nephron injury. 18 Hypertension-associated volume overload can also result in a reshaping of the afferent arteriole, 17 resulting in increased arterial stiffness. 2,19 Such stiffening can reduce arterial elasticity and result in poor vasodilation and vasoconstriction. 20–22 Reduced nephron blood flow can result in these pathophysiological changes. 23 While these mechanisms are promising, addi- tional research will be required to fully understand the mechanistic basis of our findings.
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THE EFFECT OF POSTURE ON PULMONARY CAPILLARY BLOOD FLOW IN MAN

THE EFFECT OF POSTURE ON PULMONARY CAPILLARY BLOOD FLOW IN MAN

By minimizing the shifts of blood volume ordinarily associated with changes in posture, the effect of postural change per se on cardiac output, stroke volume, and instantaneous pulmonary[r]

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POSTURAL CHANGES IN BLOOD PRESSURE IN NORMOTENSIVE PERSONS

POSTURAL CHANGES IN BLOOD PRESSURE IN NORMOTENSIVE PERSONS

Blood pressure is a measure of cardiovascular reactivity reflecting autonomic function. Also such elder ones having some associated diseases like hypertension, diabetes mellitus, and low blood volume become further weaker. The primary purpose of this study is to observe the postural variation of blood pressure and to compare.

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CHANGES IN BLOOD PRESSURE DUE TO POSTURAL VARIATION

CHANGES IN BLOOD PRESSURE DUE TO POSTURAL VARIATION

Pressure(SBP) falls with cardiac output, so the baroreceptors in the carotid arch relax and induce sympathetic stimulation. This promotes vasoconstriction and increases heart rate, which stabilizes cardiac output at a level lower than when supine. Mean blood pressure is maintained by an increase in total peripheral resistance. After a person moves from the supine to the standing position if the SBP drops more than 20 mmHg within 1 to 3 minutes, this person is said to have postural or orthostatic hypotension. Postural hypotension may be either symptomatic or asymptomatic. It may be idiopathic or may result from known causes; some of these causes are functional and reversible, whereas others have an anatomic basis and may be progressive. Blood pressure is a measure of cardiovascular reactivity reacting autonomic function. Also such elder ones having some associated diseases like hypertension, diabetes mellitus, and low blood volume become further weaker.
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Examining the breadth and burden of chronic kidney disease in community dwelling older adults

Examining the breadth and burden of chronic kidney disease in community dwelling older adults

Orthostatic hypotension (OH) refers a drop in blood pressure on standing from a sitting or lying position. Similar to CKD, OH prevalence increases with age and is associated with several cardiovascular endpoints including coronary artery disease, heart failure and stroke (93-96). Methods for detecting OH in clinical practice are rather crude, involving two or three blood pressure (BP) measurements and binary BP thresholds to define the presence or absence of OH (97). Beat-to-beat BP data are increasingly being used to better characterise dynamic BP responses after standing. Such measurements have identified a greater prevalence of impaired BP stabilisation than previously detected by conventional testing for OH (14). Failure to adequately stabilise one’s BP after standing is a predictor of injurious falls (15) and all-cause mortality (98). Given the reliance on the glomeruli for consistent regulation of blood flow to maintain adequate pressure for filtration, the kidney may be vulnerable to periodic bouts of low blood pressure due to orthostasis. On the other hand, CKD is associated with greater degrees of autonomic dysfunction, which could contribute to a greater risk of OH. Despite high prevalence of both conditions at older age, there is surprisingly little known about the relationship between OH and reduced kidney function. One previous study demonstrated an association between baseline OH and incident CKD (99). No study to date has investigated the association between postural BP responses and the kidney using beat-to-beat data.
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Mayer Wave Activity in Vasodepressor Carotid Sinus Hypersensitivity

Mayer Wave Activity in Vasodepressor Carotid Sinus Hypersensitivity

A small but statistically significant increase in total DBP and MAP variability in VDCSH was detected. Increased blood pressure varia- bility has been linked independently to end-organ damage. 26,27 Although these findings support the postulate that medullary centres maybe implicated in abnormal responses in VDCSH, 11 increases in total blood pressure variability are non-specific and could arise from a number of internal and external sources, includ- ing cardiac activity, 28 respiratory activity, 29 hypo- or hyperactive baroreflexes, 4 cognitive activation, 30 and muscle activation 24 amongst others. Wideband pressure fluctuations or increased blood pressure variance of this magnitude has been associated with blunted baroreflexes, 31 with ageing, 32 arterial stiffness, 33 in animal models with baroreflex deafferentation. 13 In such cases, increases in total blood pressure variability have been attributed to a reduced ability to modulate peripheral resistance and vascular compliance for blood pressure control in the face of internal and external disturbances.
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Soybean oil increases SERCA2a expression and left ventricular contractility in rats without change in arterial blood pressure

Soybean oil increases SERCA2a expression and left ventricular contractility in rats without change in arterial blood pressure

At the end of treatment, rats were anesthetized with ure- thane (1.2 g/kg) and a polyethylene catheter (PE50) filled with heparinized saline (50 U/mL) was introduced into the carotid artery to measure the arterial systolic blood pressure (SBP) and diastolic blood pressure (DBP). The carotid artery catheter was introduced into the left ven- tricle to measure the systolic pressure (LVSP) and its pos- itive and negative first derivatives (dP/dt max LV and dP/ dt min LV, respectively), as well as the left ventricular end diastolic pressure (LVEDP). Following this procedure, the catheter was withdrawn from the LV and the arterial pressure was measured again to determine if damage to the aortic valve had occurred. The animal was discarded if a decrease in the diastolic blood pressure was observed.
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