[PDF] Top 20 Prognostic role of CD44 expression in osteosarcoma: evidence from six studies

... The statistical analysis was carried out using the Review Manager (RevMan) software version 5.0(The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen, Denmark).All these HRs and 95% confidence interval(CI) ... See full document

... higher CD44 mRNA was identified in both colon and gastric cancer by using TCGA ...previous studies. Jing et al. [17] found that CD44 mRNA was increased in colorectal cancer tissues than that in ... See full document

... The prognostic value of lysine-specific demethylase 1 (LSD1) overexpression in various cancers has been investigated by many studies with inconsistent ...Eligible studies were identified by searching ... See full document

... increased expression of HIF-1 α . A number of studies have investigated the role of HIF-1 α expression in patients with osteosarcoma but have yielded inconsistent and inconclusive ... See full document

... of CD44 are reportedly associated with increased invasion, metastasis, and poor prognosis [30], particularly the CD44V6 ...CD44V6 expression is related to metastatic potential, prognosis, and the bio- logic ... See full document

... increased CD44 expression correlated with poor OS of HCC ...that CD44 expression correlates with favorable prognosis in breast cancer ...of CD44 survived longer and had lower recurrence ... See full document

... future studies or review previous reports [11, 46, ...key role in prognostic prediction for HCC ...high expression of CSC markers, CD133 and CD44, was predictive of poor clinical ... See full document

... important role in the regulation of mRNA ...microRNA expression with cancerogenesis as well as tumor progression is well established ...or prognostic tools for cancer [12-14]. Previous studies ... See full document

... large-scale studies with a longer follow-up time should be performed to offer more convincing ...and osteosarcoma patient survival based on multivariate ... See full document

... Previous studies have proved that miR-224 is involved in tumor formation and progression of several human can- cers ...miR-452 expression has been demonstrated in glioma [21], non-small cell lung cancer ... See full document

... of osteosarcoma. Previous studies had verified the role of microRNA-7 (miR-7) in various diseases, especially in ...of osteosarcoma. Methods: QRT-PCR was used to measure the expression ... See full document

... for studies that investi- gated the correlation of the CD44 expression and clinico- pathological parameters and prognosis in ovarian cancer ...tions from all the retrieved reports were further ... See full document

... we combined 15 publications on 1,464 patients to yield sta- tistics, indicating a statistically significant role of endocan in cancers. Combined HRs suggested that elevated endocan significantly predicts poor OS ... See full document

... I expression represented an independent factor associated with poor prognosis in pretreatment biopsy of non- localized ...I expression was significantly associated with lymphatic and nodal invasion in ... See full document

... significant prognostic factors for poor out- ...significant prognostic factor for persistence of scia- tica in the univariate but not the multivariate ... See full document

... that expression of TAZ-wild type (WT) and TAZ-S89A should rescue fascin depletion effect on melanoma ...fascin expression (Additional file 1: Figure S1). Ectopic expression of fascin in WM39 cells ... See full document

... the role of KLF4 in osteosarcoma is largely ...the expression of KLF4 was significantly increased in human osteosarcoma tissues compared with the normal ...human osteosarcoma cell ... See full document

... in osteosarcoma tissues compared to tumor adjacent ...in osteosarcoma cells transfect- ed with miR-143 mimics, suggesting the facili- tation of miR-143 on tumor cell ...of osteosarcoma is a complex ... See full document

... patients of both groups were comparable in age, tumor stage and size, local recurrence, and necrosis rate. Our results revealed no significant difference in the OS, PFS, 5-year, and 10-year survival between the two ... See full document

... the expression of functionally different splice isoforms in a spatial and temporal ...isoform expression from CD44v to CD44s, which in turn controls EMT and cancer ...as from the epithelial ... See full document