[PDF] Top 20 Prognostic value of CD44v6 expression in breast cancer: a meta-analysis

... studying CD44v6 mRNA expression (two studies), had insufficient data to conduct meta-analysis (23 studies), included fewer than 20 patients (one study), or had IHC cutoff 50% (one ...final ... See full document

... pooled analysis explored the prognostic relevance of CTC status in metastatic breast cancer, including TNBC [19], the effect of CTC status on non-metastatic TNBC still requires ... See full document

... the prognostic role of the systemic immune-inflammation index (SII) in patients with breast cancer, the results were ...the prognostic and clinicopathological value of the SII in ... See full document

... Subgroup analyses showed remarkable decrease in the heterogeneity of OS in subgroups of whole-cohort TNBC patients and high AR/ER cutoffs (Supplementary Table S3), suggesting “study population” and “AR/ER cutoff values” ... See full document

... CD133 expression and its association with clinicopathological features and ...statistical analysis of earlier studies on survival data was calculated using risk ratios ... See full document

... in cancer re- search for its crucial role in gene regulation and cancer ...or prognostic biomarker has proved by accu- mulated evidence in various types of cancer, such as colon cancer, ... See full document

... for cancer stem cells (CSCs) ...increased expression of nestin has been detected in various human malignant neoplasms, such as breast cancer [32], gliomas [35], melanomas [40], pros- tate ... See full document

... that CD44v6-positive tumor cells have CSC properties, such as self- renewal and tumorigenicity ...[27]. Expression of CD44v has been closely linked to tumor pro- gression, metastasis, and treatment ... See full document

... the CD44V6 [13]. CD44V6 promoting the metastasis of cancer has been documented and the mechanism may be attributed to its interactions with various components of the extracellular ...that ... See full document

... this meta-analysis, we analyzed 19 studies including 4803 patients, with OS data from 12 studies, DFS data from 4 studies, and RFS data from 5 studies, which revealed that a high expression of PHH3 ... See full document

... the analysis of plasma samples, all the four studies have a significant association between K-ras mutations and poorer OS, and a higher combined HR of ...the prognostic value of mutant ...with ... See full document

... current meta-analysis is the first system assessment of the pertinence of miRNA level to the prognosis of CRC ...miRNA expression is able greatly to reinforce assessment of life expectancy of CRC ... See full document

... attractive prognostic tumor ...a meta-analysis to explore the association between endocan expression and cancer ...performed. Expression of endocan and its association with ... See full document

... IHC assays and automated digital pathology analysis for SPT16 and SSRP1 were performed at the Pathology Network Shared Resource at RPCI. Formalin-fixed paraffin-embedded sections were cut at 4 µm, placed on ... See full document

... mRNA expression, by using gene-specific TaqMan ® based ...CT value of the housekeeping gene RPL37A (ribosomal protein L37a) from the CT value of the target genes ...mRNA expression level of ... See full document

... HER2 expression on tumor cells can influence tumor cell proliferation, migration, dif- ferentiation, apoptosis, and adhesion ...HER2 expression has been found in gastric ...gastric cancer with ... See full document

... the expression of the target gene PIK3R2 and influence the PTEN/PI3K/AKT signaling pathway, suppressing the proliferation, migration, and invasive abilities of A549 cells ...lung cancer cells apoptosis ... See full document

... Ang-2 expression between NSCLC tissues and normal ...the expression of Ang-2 in NSCLC tissues was significantly higher than that in normal lung tissues either through two-category variables or continuous ... See full document

... The results of our study also provided the evidence that the use of a COX-2 inhibitor could be an effective therapeutic strategy for patients with EC. COX-2 is considered to be a novel target for cancer prevention ... See full document

... independent prognostic value. Of note, we found similar prognostic results (data not shown) when PDL1 expression was analyzed as continuous value and when the molecular subtypes were ... See full document