[PDF] Top 20 Progression to the G1b Phase of the Cell Cycle Is Required for Completion of Human Immunodeficiency Virus Type 1 Reverse Transcription in T Cells
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Progression to the G1b Phase of the Cell Cycle Is Required for Completion of Human Immunodeficiency Virus Type 1 Reverse Transcription in T Cells
... of cell activation might be useful in decreasing the efficiency of reverse transcription in infected ...known virus exposure, such as that via needle stick injury or perinatal ...of ... See full document
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Preferential Cytolysis of Peripheral Memory CD4+ T Cells by In Vitro X4-Tropic Human Immunodeficiency Virus Type 1 Infection before the Completion of Reverse Transcription
... ⫹ T-cell de- pletion in AIDS have focused on uninfected CD4 ⫹ T cells, less is known about the fate of HIV-1-infected CD4 ⫹ T cells that do not express viral ...⫹ ... See full document
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The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle.
... simian virus 40 transcription termination sequences with or without the vpr open reading frame was cloned into the BSCMVThy intermedi- ate plasmid cut with NotI (blunt-ended by filling in with Klenow) and ... See full document
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Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity.
... of human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus encodes a virion-associated, nuclear protein whose role in AIDS ... See full document
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HuR interacts with human immunodeficiency virus type 1 reverse transcriptase, and modulates reverse transcription in infected cells
... HIV-1 reverse transcription is based on its interaction with p66 RT rather than its inter- action with the HIV-1 ...upon T-cell activation, following the engagement of the ... See full document
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Human immunodeficiency virus type 1 Nef increases the efficiency of reverse transcription in the infected cell.
... P4 cell line in which the expression of a b -galactosidase gene depends on the transactivation of the HIV LTR by Tat ...P4 cells 24 h after incubation with a Tat-encoding HIV stock allows a precise ... See full document
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Endogenous reverse transcription of human immunodeficiency virus type 1 in physiological microenviroments: an important stage for viral infection of nondividing cells.
... intravirion reverse transcripts in sem- inal plasma samples are significantly higher than in blood plasma ...the human body can enhance intravirion HIV-1 reverse transcription, we ... See full document
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Association of Human Immunodeficiency Virus Type 1 Vif with RNA and Its Role in Reverse Transcription
... in reverse transcription during the entry phase of the virus’s life cycle (6, 8, 30, 35, 40, ...target cells does not clearly indicate whether penetration, uncoating, virus core ... See full document
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Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Target Distinct Phases of Early Reverse Transcription
... endogenous reverse transcription (ERT) assays (39, ...microenvironment. Virus isolated from seminal plasma, which contains high levels of deoxynucleoside triphosphates (dNTPs), contained much higher ... See full document
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Diminished Human Immunodeficiency Virus Type 1 Reverse Transcription and Nuclear Transport in Primary Macrophages Arrested in Early G1 Phase of the Cell Cycle
... inoculation, cells were harvested and BrdU incorporation was visualized by a BrdU-specific monoclonal antibody and subsequent FACS ...the cells had traversed S ...proliferating cells up to ... See full document
6
Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription.
... host cell, viral genomic RNA serves as a template for the pol-encoded reverse transcriptase (RT) ...leukemia virus (MLV) DNA harvested from cells shortly after the initiation of infection is ... See full document
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Functional Domains of Tat Required for Efficient Human Immunodeficiency Virus Type 1 Reverse Transcription
... quiescent T cells can be infected by HIV-1 and reverse transcription can be initiated, full-length proviral DNA cannot be detected and integration does not take place (70, ...quiescent ... See full document
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Human Immunodeficiency Virus Type 1 Integrase Protein Promotes Reverse Transcription through Specific Interactions with the Nucleoprotein Reverse Transcription Complex
... Reverse transcription is catalyzed by RT, and although re- verse transcription can occur in vitro with recombinant RT, template, and primer, the process is more complex in ...replicating ... See full document
10
Noncytotoxic Suppression of Human Immunodeficiency Virus Type 1 Transcription by Exosomes Secreted from CD8+ T Cells
... ⫹ T cells might de- termine the cellular presentation of noncytotoxic HIV-1 sup- pression ...immune cells (28, 39, 48, ...⫹ cell surface compared to exosomes ...versus cell ... See full document
11
Differential activation of human immunodeficiency virus type 1 and 2 transcription by specific T-cell activation signals.
... In contrast, Jurkat transfectants treated with recombinant human TNF-a revealed a greater dosedependent response of HIV-1 versus HIV-2 transcription Replication of human immunodeficiency[r] ... See full document
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Vpr Cytopathicity Independent of G2/M Cell Cycle Arrest in Human Immunodeficiency Virus Type 1-Infected CD4+ T Cells
... Our site-directed mutagenesis studies suggest that the third alpha-helix of Vpr mediates diverse Vpr functions. We specu- late that this is most likely due to disruption of a crucial protein-protein interaction function ... See full document
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SIRT1 Suppresses Human T-Cell Leukemia Virus Type 1 Transcription
... of cell metab- olism and a bona fide oncoprotein in different contexts ...CREB-dependent transcription (14, ...Epstein-Barr virus and hepatitis B virus (35, 44, ...HEK293 cells were ... See full document
9
Translation Is Not Required To Generate Virion Precursor RNA in Human Immunodeficiency Virus Type 1-Infected T Cells
... HIV-1-infected human T cells were treated with translation inhibitors under conditions that maintain virus ...mock-infected T cells verifies that HIV-1 infection ... See full document
7
Nascent human immunodeficiency virus type 1 reverse transcription occurs within an enveloped particle.
... target cells may possess a higher quan- tity of gp120 than the average extracellular ...wild-type virus (33, ...target cell, those virions that have more gp120 molecules on their surface would ... See full document
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Comparison of Sequencing by Hybridization and Cycle Sequencing for Genotyping of Human Immunodeficiency Virus Type 1 Reverse Transcriptase
... Amino acid sequences were imported into Excel (version 7.0; Microsoft, Red- mond, Wash.). All differences between sequences determined by both meth- ods were noted. Additional analyses were performed with codons known to ... See full document
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