[PDF] Top 20 Recruitment of Brd4 to the Human Papillomavirus Type 16 DNA Replication Complex Is Essential for Replication of Viral DNA
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Recruitment of Brd4 to the Human Papillomavirus Type 16 DNA Replication Complex Is Essential for Replication of Viral DNA
... that Brd4 is recruited to the actively replicating HPV16 Ori along with HPV16 E1, E2, and a number of the cellular replication factors—RPA70, RFC1, and DNA poly- merase ...lication complex and ... See full document
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p53 represses human papillomavirus type 16 DNA replication via the viral E2 protein
... HPV 16 E2 protein can induce apoptosis in HPV- transformed cells via the regulation of E6/E7 expression and via a direct interaction with ...wild type E2 protein or one of the E2 mutants and a plasmid ... See full document
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Human Papillomavirus DNA Replication Compartments in a Transient DNA Replication System
... ori replication compartments and that those in BrdU-negative cells may represent pre- or postreplication ...or viral DNA contains matrix attachment sequences (2, ...active replication is the ... See full document
9
Evidence for a switch in the mode of human papillomavirus type 16 DNA replication during the viral life cycle.
... of human papillomavirus type 16 (HPV-16) replication has been impaired because of the lack of a cell culture system that stably maintains viral ...HPV-16 DNA ... See full document
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E1-Mediated Recruitment of a UAF1-USP Deubiquitinase Complex Facilitates Human Papillomavirus DNA Replication
... HPV DNA replication relies preferentially on USP1, USP12, USP46, or a combination of these ...in complex with ...the viral DNA in cells maintaining HPV episomes, but such studies are ... See full document
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Human TATA Binding Protein Inhibits Human Papillomavirus Type 11 DNA Replication by Antagonizing E1-E2 Protein Complex Formation on the Viral Origin of Replication
... of papillomavirus transcription and replication based upon interactions between host cell transcription factors and the viral E1 and E2 proteins ...the viral LCR, thereby excluding E2-LCR ... See full document
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Association of human papillomavirus 16 E2 with Rad50 interacting protein 1 enhances viral DNA replication
... however, smaller Rint1 foci that were E2 positive but Nopp140 negative were also formed (Fig. 3F). These data provide evidence that E2 relocalizes Rint1 to nuclear foci that are not associated with nucleoli. HPV16 E2 ... See full document
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Association of Human Papillomavirus 16 E2 with Rad50-Interacting Protein 1 Enhances Viral DNA Replication
... however, smaller Rint1 foci that were E2 positive but Nopp140 negative were also formed (Fig. 3F). These data provide evidence that E2 relocalizes Rint1 to nuclear foci that are not associated with nucleoli. HPV16 E2 ... See full document
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Variant Upstream Regulatory Region Sequences Differentially Regulate Human Papillomavirus Type 16 DNA Replication throughout the Viral Life Cycle
... The viral establishment phase is the first phase of the HPV life cycle during which a stable low plasmid copy number is attained within an infected cell ...phase, viral plasmids replicate more frequently ... See full document
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The E1 Protein of Human Papillomavirus Type 16 Is Dispensable for Maintenance Replication of the Viral Genome
... for viral production upon keratinocyte ...in viral DNA replication at different stages, an E1-defective mutant of the human papillomavirus 16 (HPV16) genome featuring a ... See full document
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An Interaction between Human Papillomavirus 16 E2 and TopBP1 Is Required for Optimum Viral DNA Replication and Episomal Genome Establishment
... In human papillomavirus DNA replication, the viral protein E2 forms homodimers and binds to 12-bp palindromic DNA se- quences surrounding the origin of DNA ...the ... See full document
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Different Modes of Human Papillomavirus DNA Replication during Maintenance
... cellular DNA. Although this may indicate that the viral and cellular DNA replicated in step, it is not by any means a proof of ...cellular DNA replication occurs only once per cell ... See full document
9
Viral DNA Replication Orientation and hnRNPs Regulate Transcription of the Human Papillomavirus 18 Late Promoter
... of replication activates the late promoter remains to be determined, our data suggest that a replication fork moving toward the late promoter in one direction may be essential for ...that ... See full document
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Uracil DNA Glycosylase BKRF3 Contributes to Epstein-Barr Virus DNA Replication through Physical Interactions with Proteins in Viral DNA Replication Complex
... with viral proteins in replication complexes promoted EBV DNA replication through enzymatic activity-independent ...and DNA binding domain, was crucial for association with other ... See full document
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Recruitment of Replication Protein A by the Papillomavirus E1 Protein and Modulation by Single-Stranded DNA
... of viral proteins E1 and E2, papillomaviruses depend heavily on host replication machinery for replication of their viral ...cellular replication factors to the viral origin of ... See full document
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mRNA Splicing Regulates Human Papillomavirus Type 11 E1 Protein Production and DNA Replication
... The papillomavirus replicative helicase E1 and the origin recognition protein E2 are required for efficient viral DNA ...the human papillomavirus type 11 E1 protein either in a ... See full document
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The Carboxyl-Terminal Region of the Human Papillomavirus Type 16 E1 Protein Determines E2 Protein Specificity during DNA Replication
... of replication than HPV-11 proteins ...the viral proteins, to differences in levels of protein expression, or ...in replication that may have originated from variances in protein translation ... See full document
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Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions.
... of papillomavirus play key roles in viral replication, both as regulators of viral transcription and as auxiliary factors that act with E1 in viral DNA ...the human ... See full document
10
Werner Helicase Control of Human Papillomavirus 16 E1 E2 DNA Replication Is Regulated by SIRT1 Deacetylation
... E1-E2 replication complex, but in the absence of SIRT1, there are elevated acetylation levels of WRN and an increased level of the ...E1-E2 replication reduces the half-life of the WRN protein, and ... See full document
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The Viral E8^E2C Repressor Limits Productive Replication of Human Papillomavirus 16
... Papillomavirus 16 Elke Straub, Marcel Dreer, Jasmin Fertey, Thomas Iftner, Frank Stubenrauch University Hospital Tübingen, Institute for Medical Virology and Epidemiology of Viral Diseases, Division ... See full document
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